Abstract: The present invention relates to substantially homogenous populations of human retinal progenitor cells having the following positive surface markers: SSEA4, CD73, PTK7 and PSA-NCAM. The invention also relates to method for preparing such substantially homogeneous cell populations from human tissue using cell sorting techniques.

Abstract: The present disclosure provides methods for preparing MCL1 inhibitors or a salt thereof and related key intermediates.

Abstract: Methods and apparatus for stamp generation are disclosed using nano-resist and ultra violet blocking materials. In one non-limiting embodiment, a method of producing a copy of a stamp for generating electrical/optical components is disclosed comprising: providing the stamp; coating a bottom surface of the stamp with a ultra violet blocking material; curing the ultra violet blocking material on the bottom surface; contacting the stamp to a target substrate covered with a layer of imprint resist; curing the imprint resist with ultraviolet blocking material during the contacting of the stamp to the target substrate; and releasing the stamp from the target substrate with the cured layer of imprint resist.

Abstract: Methods and apparatus for stamp generation are disclosed using nano-resist and ultra violet blocking materials. In one non-limiting embodiment, a method of producing a copy of a stamp for generating electrical/optical components is disclosed comprising: providing the stamp; coating a bottom surface of the stamp with a ultra violet blocking material; curing the ultra violet blocking material on the bottom surface; contacting the stamp to a target substrate covered with a layer of imprint resist; curing the imprint resist with ultraviolet blocking material during the contacting of the stamp to the target substrate; and releasing the stamp from the target substrate with the cured layer of imprint resist.

Abstract: Forming an imaging blanket for a printing apparatus includes depositing a patternable material over a substrate, etching the patternable material according to a desired exposure pattern, hardening the etched patternable material to thereby form a template surface comprising a desired template pattern of texture features, depositing a layer of curable liquid polymer over and in physical contact with the template surface, curing the liquid polymer to thereby form the imaging blanket, and removing the imaging blanket from the template surface to thereby expose a patterned imaging surface of the imaging blanket. The image blanket may thereby be provided with a desired texture surface, for example comprised of individual molded image blanket features, such as recesses or pillars, of a desired cross-sectional shape. The image blanket is configured for and may be disposed on an image forming member of a variable data lithography system.

Abstract: Forming an imaging blanket for a printing apparatus includes depositing a patternable material over a substrate, etching the patternable material according to a desired exposure pattern, hardening the etched patternable material to thereby form a template surface comprising a desired template pattern of texture features, depositing a layer of curable liquid polymer over and in physical contact with the template surface, curing the liquid polymer to thereby form the imaging blanket, and removing the imaging blanket from the template surface to thereby expose a patterned imaging surface of the imaging blanket. The image blanket may thereby be provided with a desired texture surface, for example comprised of individual molded image blanket features, such as recesses or pillars, of a desired cross-sectional shape. The image blanket is configured for and may be disposed on an image forming member of a variable data lithography system.

Abstract: A method of forming an imaging blanket for a printing apparatus comprises preparing a support structure (e.g., mold) for receipt of a polymer blanket compound, introducing the polymer blanket compound in liquid state over the support structure, curing the polymer blanket compound to produce an imaging blanket, releasing the imaging blanket from the support structure, and etching a surface of the imaging blanket to form a texture pattern therein, the surface forming an imaging surface of said imaging blanket. An imaging surface providing desirable dampening fluid retention is provided. Wet etch, dry etch or a combination of both may be used. The polymer may be a silicone compound, may include 3 percent by weight granular material.

Abstract: Forming an imaging blanket for a printing apparatus includes depositing a patternable material over a substrate, etching the patternable material according to a desired exposure pattern, hardening the etched patternable material to thereby form a template surface comprising a desired template pattern of texture features, depositing a layer of curable liquid polymer over and in physical contact with the template surface, curing the liquid polymer to thereby form the imaging blanket, and removing the imaging blanket from the template surface to thereby expose a patterned imaging surface of the imaging blanket. The image blanket may thereby be provided with a desired texture surface, for example comprised of individual molded image blanket features, such as recesses or pillars, of a desired cross-sectional shape. The image blanket is configured for and may be disposed on an image forming member of a variable data lithography system.

Abstract: A method of forming an imaging blanket for a printing apparatus comprises preparing a support structure (e.g., mold) for receipt of a polymer blanket compound, introducing the polymer blanket compound in liquid state over the support structure, curing the polymer blanket compound to produce an imaging blanket, releasing the imaging blanket from the support structure, and etching a surface of the imaging blanket to form a texture pattern therein, the surface forming an imaging surface of said imaging blanket. An imaging surface providing desirable dampening fluid retention is provided. Wet etch, dry etch or a combination of both may be used. The polymer may be a silicone compound, may include 3 percent by weight granular material.

Abstract: Forming an imaging blanket for a printing apparatus includes depositing a patternable material over a substrate, etching the patternable material according to a desired exposure pattern, hardening the etched patternable material to thereby form a template surface comprising a desired template pattern of texture features, depositing a layer of curable liquid polymer over and in physical contact with the template surface, curing the liquid polymer to thereby form the imaging blanket, and removing the imaging blanket from the template surface to thereby expose a patterned imaging surface of the imaging blanket. The image blanket may thereby be provided with a desired texture surface, for example comprised of individual molded image blanket features, such as recesses or pillars, of a desired cross-sectional shape. The image blanket is configured for and may be disposed on an image forming member of a variable data lithography system.

Abstract: A side-firing printhead comprises a stack that includes a plurality of slices, wherein each slice includes a PCB trigger layer and a diaphragm layer, the PCB trigger layer controls the flow of ink from the diaphragm layer, a first side of the diaphragm layer includes at least one cavity that delivers ink via one or more aperture braces. An aperture plate is coupled to one side of the stack to interface to the diaphragm layers contained therein, wherein the aperture plate contains a plurality of apertures that are located at each aperture brace. A first bracket is disposed on the top of the stack and a second bracket is disposed on the bottom of the stack, wherein at least one fastener couples the second bracket to the first bracket such that a predetermined amount of pressure is applied to the stack.

Abstract: A drop generator having a via structure configured for electrical and fluidic interconnection. The via structure includes an electrically conductive layer and an electrically insulating layer disposed on the electrically conductive layer.

Abstract: A side-firing printhead comprises a stack that includes a plurality of slices, wherein each slice includes a PCB trigger layer and a diaphragm layer, the PCB trigger layer controls the flow of ink from the diaphragm layer, a first side of the diaphragm layer includes at least one cavity that delivers ink via one or more aperture braces. An aperture plate is coupled to one side of the stack to interface to the diaphragm layers contained therein, wherein the aperture plate contains a plurality of apertures that are located at each aperture brace. A first bracket is disposed on the top of the stack and a second bracket is disposed on the bottom of the stack, wherein at least one fastener couples the second bracket to the first bracket such that a predetermined amount of pressure is applied to the stack.

Abstract: A via structure configured for electrical and fluidic interconnection, and including an electrically conductive layer and an electrically insulating layer disposed on the electrically conductive layer.

Abstract: A drop generator having a via structure configured for electrical and fluidic interconnection. The via structure includes an electrically conductive layer and an electrically insulating layer disposed on the electrically conductive layer.

Abstract: A system and method for environmental data management. The system includes an application including a mapping module that a generates an interactive graphical mapping interface of the site, the interactive mapping interface including links to environmental data from a site and related documents, an analysis module that analyzes the environmental data, the environmental data including contaminants of potential concern (COPC) data, a risk assessment module that assesses the human health risks caused by COPCs at the site, and a remediation module that screens remedial technology for cleaning up COPCs.

Abstract: A crud-resistant nuclear fuel element cladding in which the axial locations that experience nucleate boiling during reactor full power operation are highly polished so that the maximum size of any surface defect on the highly polished surface is approximately 0.1 microns. The remainder of the cladding surface remains unpolished so that crud is more evenly redistributed over the entire fuel cladding surface to limit the thickness of the crud that is formed to less than 35 microns.

Abstract: Method of printing with ultraviolet photosensitive resin-containing materials includes depositing at least one substance that includes an ultraviolet photosensitive resin on to a substrate, partially curing the substance by irradiating the substance with at least one ultraviolet light emitting device, and completely curing the substance. Substance curing system including a substrate, an applicator that deposits a substance that includes an ultraviolet photosensitive resin on to a substrate, and at least one ultraviolet light emitting device usable to irradiate the substance to partially cure and/or completely cure the substance.

Abstract: Method of printing with ultraviolet photosensitive resin-containing materials includes depositing at least one substance that includes an ultraviolet photosensitive resin on to a substrate, partially curing the substance by irradiating the substance with at least one ultraviolet light emitting device, and completely curing the substance. Substance curing system including a substrate, an applicator that deposits a substance that includes an ultraviolet photosensitive resin on to a substrate, and at least one ultraviolet light emitting device usable to irradiate the substance to partially cure and/or completely cure the substance.

Abstract: Method of ejecting or depositing a substance includes depositing at least one substance that includes first and second photoinitiators onto a substrate, causing the first photoinitiator to react by irradiating the substance with at least one light, and causing the second photoinitiator to react by irradiating the substance with at least one light. Substance ejecting or depositing system including a substrate, an applicator that deposits a substance that includes first and second photoinitiators onto a substrate, and at least one light usable to irradiate the substance to cause the first and/or second photoinitiators to react.