Patents by Inventor Michael Yu
Michael Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250118773Abstract: An interconnect for an electrochemical stack includes at least one of alternating air channel ribs of different length, seal gutters recessed relative to a perimeter seal surface on a fuel side of the interconnect, or fuel inlet and outlet plenums which extend perpendicular to fuel channels.Type: ApplicationFiled: September 16, 2024Publication date: April 10, 2025Inventors: Michael GASDA, Chad FOLKMAN, Cheng-Yu LIN, Travis A. SCHMAUSS, Zigui LU, Haomin LU, Prabu SOMASUNDARAM, Nilanjana BASU, Annamalai RAMAN
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Patent number: 12269840Abstract: The invention generally relates to an improved processes for the preparation of a cyclic dinucleotide which is useful as a STING agonist of the following formula (I), involving the use of compounds A and B.Type: GrantFiled: December 3, 2019Date of Patent: April 8, 2025Assignee: BRISTOL-MYERS SQUIBB COMPANYInventors: Michael Anthony Schmidt, Bin Zheng, Benjamin M. Cohen, Amanda J. Rogers, Changxia Yuan, Jason J. Zhu, Chao Hang, Daniel S. Treitler, Adam Joseph Freitag, Geoffrey Eugene Purdum, Miao Yu, Melda Sezen Edmonds, Siwei Guo
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Patent number: 12268694Abstract: The present invention relates to a pharmaceutical composition useful for treating a Respiratory Syncytial Virus (RSV) infection, comprising a compound which is or a pharmaceutically acceptable salt thereof, and a second anti-respiratory syncytial virus agent.Type: GrantFiled: November 10, 2020Date of Patent: April 8, 2025Assignee: Enanta Pharmaceuticals, Inc.Inventors: Brian C. Shook, In Jong Kim, Thomas P. Blaisdell, Jianming Yu, Joseph Panarese, Kai Lin, Michael H. J. Rhodin, Nicole V. McAllister, Yat Sun Or
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Publication number: 20250108132Abstract: Compositions and methods for reducing complement activation by introducing one or more alterations into a complement component 3 (C3) polynucleotide in a cell. In particular embodiments, the disclosure features a base editor system (e.g., a fusion protein or complex comprising a programmable DNA binding protein, a nucleobase editor, and gRNA) for modifying a C3 polynucleotide, where the modification is associated with reduced expression, and/or reduced activity of the C3 polypeptide encoded by the polynucleotide.Type: ApplicationFiled: December 12, 2024Publication date: April 3, 2025Applicant: Beam Therapeutics Inc.Inventors: Michael S. Packer, Christopher Fincher, Tanggis Bohnuud, Yi Yu, Nicole Gaudelli, Brian Cafferty
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Publication number: 20250104365Abstract: For artificial reality (XR) applications that need a guardian, aspects of the present disclosure can automatically determine where boundaries should be set in the real-world environment. Using a machine learning model, the automatic boundary system can detect the floor plane, then generate a height map of the real-world environment with the floor at zero. The height map can include positive heights (e.g., objects on the floor) and negative heights (e.g., downward leading stairs). The automatic boundary system can then generate a boundary for the area based on the detected heights by: applying thresholds to disregard objects at certain heights, applying thresholds to disregard open areas at certain widths, excluding oddly shaped areas that would constantly trigger the boundary if the user were nearby, etc. The user can further manually adjust the generated boundary in both directions (e.g., bringing it closer or further from the user).Type: ApplicationFiled: July 12, 2024Publication date: March 27, 2025Inventors: Asaf NITZAN, Ariana Yu-Chia HARVEY, Jasmine OU, Ting Ting WU, Christopher Richard TANNER, Muqing NIU, Peter JU, Eric LEUNG, James Alexander VALORI, Michael CASTILLO, Adi PERRY, Dan KLARMAN, Einav Namer YELIN, Tal Haim Ben BASAT, Jeremie GUEDJ, Alon LERNER, Savitha Yalanadu SHIVAIAH
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Publication number: 20250100406Abstract: A charging connector adapter is nested within a holster of an electric vehicle supply equipment (EVSE). If the adapter is to be used, the EVSE automatically locks the charging connector to the charging connector adapter and unlocks the charging connector adapter from the holster of the EVSE thereby allowing the charging cable with the charging connector adapter to be removed from the holster and used for connecting the charging connector adapter to an inlet of an electric vehicle. When the charging connector adapter is inserted back into the holster, the EVSE locks the charging connector to the holster and unlocks the charging connector from the charging connector adapter.Type: ApplicationFiled: September 26, 2024Publication date: March 27, 2025Inventors: William Rich, Parth Sanjiv Gyani, Tung-Po Yang, Jacky S. Wong, Gopalakrishna Ranjan Melpal, Jeffrey T. Barone, Hossein Kazemi, Dennis Michael Heleine, Masoud Yazdanian, John Hsudan Yu
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Publication number: 20250092008Abstract: The present disclosure provides the methods for making 4-[4-cyano-2-({[(2?R,4S)-6-(isopropylcarbamoyl)-2,3-dihydrospiro[chromene-4,1?-cyclopropan]-2?-yl]carbonyl}amino)phenyl]butanoic acid. The present disclosure also generally relates to intermediates useful in the said methods.Type: ApplicationFiled: August 9, 2022Publication date: March 20, 2025Applicant: ONO PHARMACEUTICAL CO., LTD.Inventors: Ryoichi ARIHARA, Naoya SAGAWA, Michael Bryan HAY, Sarah Evelyn STEINHARDT, Steven R. WISNIEWSKI, John Ryan COOMBS, Gregory Louis BEUTNER, Patricia Y. CHO, Carlos A. GUERRERO, Miao YU, Xuelei GUO
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Publication number: 20250090661Abstract: Provided herein, inter alia, are methods for expanding a population of human group 2 innate lymphoid cells (ILC2), and methods of treating cancer in a subject including administering to the subject the population of expanded human ILC2. Further provided are genetically engineered human ILC2s including chimeric antigen receptors, and methods of treating cancer in a subject including administering to the subject the genetically engineered human ILC2.Type: ApplicationFiled: July 26, 2024Publication date: March 20, 2025Inventors: Jianhua YU, Michael A. CALIGIURI
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Publication number: 20250084072Abstract: The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.Type: ApplicationFiled: August 20, 2024Publication date: March 13, 2025Inventors: Gediminas J. Brizgys, Chienhung Chou, Jeromy J. Cottell, Chao-I Hung, Michael L. Mitchell, James G. Taylor, Rhiannon Thomas-Tran, Nathan E. Wright, Zheng-Yu Yang, Sheila M. Zipfel
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Publication number: 20250086370Abstract: An example apparatus includes interface circuitry, machine-readable instructions, and at least one processor circuit to be programmed by the machine-readable instructions to identify crosstalk between a first signal via and a second signal via on a printed circuit board (PCB) layout, determine an area for placement of a ground via between the first signal via and the second signal via, and classify one or more regions of the PCB layout into at least one of a protective area or a non-protective area based on the area for placement of the ground via.Type: ApplicationFiled: November 25, 2024Publication date: March 13, 2025Applicant: Intel CorporationInventors: Kuan-Yu Chen, Michael Wilmer Leddige, Diego Mauricio Cortes Hernandez, John Sharpe
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Patent number: 12246008Abstract: Disclosed are compounds of Formula (I), Formula (II), or a salt thereof: Formula (I) Formula (II) which compounds have properties for inhibiting Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula (I), Formula (II) or their salts, and methods of treating pain disorders, cough, and itch using the same.Type: GrantFiled: December 2, 2019Date of Patent: March 11, 2025Assignee: Merck Sharp & Dohme LLCInventors: Christopher J. Bungard, Helen Y. Chen, Jason M. Cox, Liangqin Guo, Michael J. Kelly, III, Ronald M. Kim, Mark E. Layton, Hong Liu, Jian Liu, Mehul F. Patel, James J. Perkins, Deping Wang, Walter Won, Younong Yu, Ting Zhang
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Publication number: 20250074527Abstract: A mounting bracket for a foldable transport device includes a top portion, a bottom portion, a front wall connecting the top portion and the bottom portion, a first foot peg mounted to the mounting bracket by a first pin and moveably connected to the mounting bracket between a stowed configuration and a riding configuration, and a second foot peg mounted to the mounting bracket by a second pin and moveably connected to the mounting bracket between a stowed configuration and a riding configuration.Type: ApplicationFiled: August 31, 2023Publication date: March 6, 2025Inventors: Nicholas P. ZIRALDO, Matthew B. STAAL, Michael Jin KIM, Jackie P . PORCHAY, Ming Hsein LEE, Ding Jong CHOU, Sheng Yu HUANG
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Publication number: 20250075048Abstract: The invention provides polyurethane and polyisocyanurate foams and methods for the preparation thereof. More particularly, the invention relates to closed-celled, polyurethane and polyisocyanurate foams and methods for their preparation. The foams are characterized by a fine uniform cell structure and little or no foam collapse. The foams are produced with a polyol premix composition which comprises a combination of a hydrohaloolefin blowing agent, a polyol, a silicone surfactant, and a precipitation-resistant metal-based catalyst used alone or in combination with an amine catalyst.Type: ApplicationFiled: September 9, 2024Publication date: March 6, 2025Applicant: HONEYWELL INTERNATIONAL INC.Inventors: Bin Yu, Mary C. Bogdan, Clifford P. Gittere, Michael Ross, Ronald S. Grossman, David J. Williams
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Patent number: 12242373Abstract: Systems, devices, media, and methods are presented for testing the capability of a mobile device to run a particular feature of an application. Each feature may include a package of code, a call, a state, and a condition; each condition correlated with a specific state. The call is a query that includes instructions to evaluate whether the application will run successfully if a particular feature is running. If the call fails, the feature condition remains Off, resulting in a rollback of the feature. If the call succeeds, the feature condition is changed to On. The system may include an experimentation framework on each mobile device for registering features, executing calls, logging results, and maintaining states and conditions.Type: GrantFiled: January 31, 2022Date of Patent: March 4, 2025Assignee: Snap Inc.Inventors: Michael Cieslak, Jiayao Yu, Kai Chen, Farnaz Azmoodeh, Michael David Marr, Jun Huang, Zahra Ferdowsi
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Publication number: 20250064228Abstract: A frame apparatus, a kit of parts which includes multiple frames and a connector bracket for connecting the frames together, and a method of interconnecting a plurality of frames and hanging the same from a support surface. The frame apparatus may be a front-loading frame whereby display items are inserted into a display cavity of the frame through an opening in the front surface of the frame through which the display cavity is viewed. The frame may include an outer annular wall that defines the display cavity, an inner annular wall that is spaced apart from the outer annular wall, and a floor that extends between the inner and outer annular walls. The floor may comprise a plurality of apertures to allow for attachment of the frame to various accessories including hanging brackets, connector brackets, trays, and the like.Type: ApplicationFiled: November 11, 2024Publication date: February 27, 2025Applicant: MCS Industries, Inc.Inventors: Michael Lee Pyle, Robert Terry Coyle, JR., Matthew Scott Kressin, Jill Christine Heck, Weisha YU, Isabel Kathleen Case, Ariane Ebba Boli, Brad William Huff
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Patent number: 12237589Abstract: Millimeter wave (mmWave) technology, apparatuses, and methods that relate to transceivers, receivers, and antenna structures for wireless communications are described. The various aspects include co-located millimeter wave (mmWave) and near-field communication (NFC) antennas, scalable phased array radio transceiver architecture (SPARTA), phased array distributed communication system with MIMO support and phase noise synchronization over a single coax cable, communicating RF signals over cable (RFoC) in a distributed phased array communication system, clock noise leakage reduction, IF-to-RF companion chip for backwards and forwards compatibility and modularity, on-package matching networks, 5G scalable receiver (Rx) architecture, among others.Type: GrantFiled: May 2, 2022Date of Patent: February 25, 2025Assignee: Intel CorporationInventors: Erkan Alpman, Arnaud Lucres Amadjikpe, Omer Asaf, Kameran Azadet, Rotem Banin, Miroslav Baryakh, Anat Bazov, Stefano Brenna, Bryan K. Casper, Anandaroop Chakrabarti, Gregory Chance, Debabani Choudhury, Emanuel Cohen, Claudio Da Silva, Sidharth Dalmia, Saeid Daneshgar Asl, Kaushik Dasgupta, Kunal Datta, Brandon Davis, Ofir Degani, Amr M. Fahim, Amit Freiman, Michael Genossar, Eran Gerson, Eyal Goldberger, Eshel Gordon, Meir Gordon, Josef Hagn, Shinwon Kang, Te Yu Kao, Noam Kogan, Mikko S. Komulainen, Igal Yehuda Kushnir, Saku Lahti, Mikko M. Lampinen, Naftali Landsberg, Wook Bong Lee, Run Levinger, Albert Molina, Resti Montoya Moreno, Tawfiq Musah, Nathan G. Narevsky, Hosein Nikopour, Oner Orhan, Georgios Palaskas, Stefano Pellerano, Ron Pongratz, Ashoke Ravi, Shmuel Ravid, Peter Andrew Sagazio, Eren Sasoglu, Lior Shakedd, Gadi Shor, Baljit Singh, Menashe Soffer, Ra'anan Sover, Shilpa Talwar, Nebil Tanzi, Moshe Teplitsky, Chintan S. Thakkar, Jayprakash Thakur, Avi Tsarfati, Yossi Tsfati, Marian Verhelst, Nir Weisman, Shuhei Yamada, Ana M. Yepes, Duncan Kitchin
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Patent number: 12229035Abstract: Systems, devices, media, and methods are presented for releasing an application feature in incremental stages while monitoring the application for anomalies. The feature includes a package of code and an action setting. The methods in some implementations include identifying active devices on which the application has been installed, monitoring the application according to a set of metrics, activating the feature by changing its action setting for a first segment of the active devices, pausing the feature if an anomaly is detected among the set of metrics, and generating a repair ticket. As long as no anomaly is detected, the activating step proceeds for subsequent segments of the active devices, iteratively, until the release is completed. A feature rank may be used to process and release a plurality of features in order of priority.Type: GrantFiled: November 3, 2023Date of Patent: February 18, 2025Assignee: Snap Inc.Inventors: Michael Cieslak, Jiayao Yu, Kai Chen, Farnaz Azmoodeh, Michael David Marr, Jun Huang, Zahra Ferdowsi, Olamide Valerie Olatunji, David Boyle, Claire Reinert
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Publication number: 20250053751Abstract: Implementations relate to generating multi-modal response(s) through utilization of large language model(s) (LLM(s)). Processor(s) of a system can: receive natural language (NL) based input, generate a multi-modal response that is responsive to the NL based output, and cause the multi-modal response to be rendered. In some implementations, and in generating the multi-modal response, the processor(s) can process, using a LLM, LLM input (e.g., that includes at least the NL based input) to generate LLM output, and determine, based on the LLM output, textual content for inclusion in the multi-modal response and multimedia content for inclusion in the multi-modal response. In some implementations, the multimedia content can be obtained based on a multimedia content tag that is included in the LLM output and that is indicative of the multimedia content. In various implementations, the multimedia content can be interleaved between segments of the textual content.Type: ApplicationFiled: January 16, 2024Publication date: February 13, 2025Inventors: Oscar Akerlund, Evgeny Sluzhaev, Golnaz Ghiasi, Thang Luong, Yifeng Lu, Igor Petrovski, Agoston Weisz, Wei Yu, Rakesh Shivanna, Michael Andrew Goodman, Apoorv Kulshreshtha, Yu Du, Amin Ghafouri, Sanil Jain, Dustin Tran, Vikas Peswani, YaGuang Li
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Patent number: 12224808Abstract: An optimization method of automatically optimizing a performance parameter of a signal generator circuit is described. An RF output signal is generated by the signal generator circuit. A performance parameter of the signal generator circuit is determined based on the RF output signal by the control circuit. At least one operational parameter of the signal generator circuit is adapted by the control circuit in order to optimize the performance parameter. Further, a signal generator circuit is described.Type: GrantFiled: December 9, 2022Date of Patent: February 11, 2025Assignee: Rohde & Schwarz GmbH & Co. KGInventors: Ajan Joshi, Florian Fischbacher, Haisang Yu, Chlodwig Neuhaeusler, Michael Koenig
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Publication number: 20250045521Abstract: In accordance with an embodiment, described herein is a system and method for use of text analytics to transform, analyze, and visualize data, including support for data flows of unstructured text or other types of textual data input. Additionally described are various examples of algorithmic processes and user interfaces that can be used to enable text analytics in particular environments or use cases. In accordance with an embodiment, the system can be implemented within a cloud environment that enables self-service text analytics. A user, for example an organizational business user who may not be expert in the use of machine learning as applied to data processing, can interact with the system via a user interface, to apply natural language processing or other text analysis techniques to a data flow or set of input data, to generate visualizations or other types of useful information associated with the data.Type: ApplicationFiled: October 23, 2024Publication date: February 6, 2025Inventors: MICHAEL MALAK, MANISHA GUPTA, NIKHIL SURVE, CHAOHUI YU, LUIS E. RIVAS, LUIS RAMIREZ, DOUGLAS SAVOLAINEN
