Patents by Inventor Michael Zasloff

Michael Zasloff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating Parkinson's disease using aminosterols and compositions comprising the same
    Patent number: 10633413
    Abstract: This invention relates to methods of stimulating the activity of the human and animal enteric nervous system. The method comprises orally administering an aminosterol, such as squalamine, a naturally occurring aminosterol isolated from Squalus acanthias, or derivatives thereof, to a subject in need.
    Type: Grant
    Filed: July 13, 2018
    Date of Patent: April 28, 2020
    Assignee: ENTERIN, INC.
    Inventor: Michael Zasloff
  • METHODS AND COMPOSITIONS FOR TREATING COGNITIVE IMPAIRMENT
    Publication number: 20200038417
    Abstract: This invention relates to methods of treating, preventing, and/or slowing the onset or progression of cognitive impairment and/or a cognitive impairment related symptom in a subject in need. The methods, which utilize a patient-specific “fixed dose” of an aminosterol, comprise administering a therapeutically effective dose of an aminosterol to a subject in need.
    Type: Application
    Filed: August 2, 2019
    Publication date: February 6, 2020
    Applicant: Enterin, Inc.
    Inventors: Denise Barbut, Michael Zasloff
  • METHODS OF TREATING MULTIPLE SYSTEM ATROPHY USING AMINOSTEROL COMPOSITIONS
    Publication number: 20200038419
    Abstract: The present application relates generally to compositions and methods for treating, preventing, and/or slowing the onset or progression of multiple system atrophy (MSA) and a variety of symptoms related thereto with aminosterols or pharmaceutically acceptable salts or derivatives thereof.
    Type: Application
    Filed: August 2, 2019
    Publication date: February 6, 2020
    Applicant: Enterin, Inc.
    Inventors: Denise Barbut, Michael Zasloff
  • METHODS OF TREATING ALZHEIMER'S DISEASE USING AMINOSTEROL COMPOSITIONS
    Publication number: 20200038412
    Abstract: The present application relates generally to compositions and methods for treating, preventing, and/or slowing the onset or progression of Alzheimer's disease (AD) and a variety of symptoms related thereto with amino sterols or pharmaceutically acceptable salts or derivatives thereof.
    Type: Application
    Filed: August 2, 2019
    Publication date: February 6, 2020
    Applicant: Enterin, Inc.
    Inventors: Denise Barbut, Michael Zasloff
  • METHODS OF TREATING PARKINSON'S DISEASE USING AMINOSTEROL COMPOSITIONS
    Publication number: 20200038413
    Abstract: The present application relates generally to compositions and methods for treating and/or preventing Parkinson's disease and symptoms related thereto with with compositions comprising at least one aminosterol or a pharmaceutically acceptable salt or derivative thereof.
    Type: Application
    Filed: August 2, 2019
    Publication date: February 6, 2020
    Applicant: Enterin, Inc.
    Inventors: Denise Barbut, Michael Zasloff
  • METHODS OF TREATING CONSTIPATION USING AMINOSTEROL COMPOSITIONS
    Publication number: 20200038414
    Abstract: This invention relates to methods of treating constipation and constipation-related symptoms in a subject in need. The methods, which utilize a patient-specific “fixed dose” of an aminosterol, comprise administering a therapeutically effective dose of an aminosterol to a subject in need.
    Type: Application
    Filed: August 2, 2019
    Publication date: February 6, 2020
    Applicant: Enterin, Inc.
    Inventors: Denise Barbut, Michael Zasloff
  • AMINOSTEROL COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATING DEPRESSION
    Publication number: 20200038420
    Abstract: The present application relates generally to methods for treating, preventing, and/or slowing the onset or progression of depression and a variety of symptoms related thereto with aminosterols or pharmaceutically acceptable salts or derivatives thereof.
    Type: Application
    Filed: August 2, 2019
    Publication date: February 6, 2020
    Applicant: Enterin, Inc.
    Inventors: Denise Barbut, Michael Zasloff
  • METHODS OF TREATING AUTISM SPECTRUM DISORDER USING AMINOSTEROL COMPOSITIONS
    Publication number: 20200038418
    Abstract: The present application relates generally to compositions and methods for treating, preventing, and/or slowing the onset or progression of autism spectrum disorder (ASD) and a variety of symptoms related thereto with aminosterols or pharmaceutically acceptable salts or derivatives thereof.
    Type: Application
    Filed: August 2, 2019
    Publication date: February 6, 2020
    Applicant: Enterin, Inc.
    Inventors: Denise Barbut, Michael Zasloff
  • METHODS OF TREATING CARDIAC CONDUCTION DEFECTS USING AMINOSTEROL COMPOSITIONS
    Publication number: 20200038416
    Abstract: The present application relates generally to compositions and methods for treating, preventing, and/or slowing the onset or progression of cardiac conduction defects (CCDs) and a variety of symptoms related thereto with amino sterols or pharmaceutically acceptable salts or derivatives thereof.
    Type: Application
    Filed: August 2, 2019
    Publication date: February 6, 2020
    Applicant: Enterin, Inc.
    Inventors: Denise Barbut, Michael Zasloff
  • METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING VIRAL INFECTIONS
    Publication number: 20200000825
    Abstract: A method of treating or preventing a systemic viral infection in a mammal by administering a pharmaceutically acceptable composition selected from the group consisting of squalamine, an active isomer thereof, and an active analogue thereof, via a dosing regimen that delivers effective antiviral concentrations of squalamine. Also compositions for achieving the systemic antiviral effect.
    Type: Application
    Filed: September 3, 2019
    Publication date: January 2, 2020
    Applicant: ENTERIN LABORATORIES, INC.
    Inventor: Michael Zasloff
  • METHODS AND COMPOSITIONS FOR TREATING AND/OR PREVENTING THE PROGRESSION AND/OR ONSET OF AGE-RELATED NEURODEGENERATION
    Publication number: 20190381071
    Abstract: This invention relates to methods of treating and/or preventing the progression and/or onset of age-related neurodegeneration. The invention also relates to methods of reversibly slowing the growth and/or aging of a subject, and/or extending the potential lifespan of the subject, comprising administration of the naturally occurring aminosterol MSI-1436, or derivatives or salts thereof. Also described are methods of treating, preventing or delaying the onset of age-related diseases or conditions comprising administration of Aminosterol 1436, or derivatives or salts thereof.
    Type: Application
    Filed: June 13, 2019
    Publication date: December 19, 2019
    Applicant: Enterin, Inc.
    Inventors: Michael Zasloff, Denise Barbut
  • Methods and compositions for treating and preventing viral infections
    Patent number: 10478444
    Abstract: A method of treating or preventing a systemic viral infection in a mammal by administering a pharmaceutically acceptable composition selected from the group consisting of squalamine, an active isomer thereof, and an active analogue thereof, via a dosing regimen that delivers effective antiviral concentrations of squalamine. Also compositions for achieving the systemic antiviral effect.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: November 19, 2019
    Assignee: Enterin, Inc.
    Inventor: Michael Zasloff
  • METHODS AND COMPOSITIONS FOR TREATING HALLUCINATIONS AND CONDITIONS RELATED TO THE SAME
    Publication number: 20190298740
    Abstract: This application relates to methods of treating, preventing and/or slowing the onset or progression of hallucinations and/or related symptoms caused by a variety disorders, with aminosterols or pharmaceutically acceptable salts or derivatives thereof.
    Type: Application
    Filed: March 25, 2019
    Publication date: October 3, 2019
    Applicant: Enterin, Inc.
    Inventors: Denise Barbut, Michael Zasloff
  • METHODS OF PREVENTING DEPRESSION AND SYMPTOMS THEREOF USING AMINOSTEROLS
    Publication number: 20190194244
    Abstract: This invention relates to methods of stimulating the activity of the human and animal enteric nervous system. The method comprises orally administering an aminoserol, such as squalamine, a naturally occurring aminosterol isolated from Squalus acanthias, or derivatives thereof, to a subject in need.
    Type: Application
    Filed: December 14, 2018
    Publication date: June 27, 2019
    Applicant: Enterin Laboratories, Inc.
    Inventor: Michael Zasloff
  • METHODS OF TREATING AND PREVENTING GASTROINTESTINAL MOTILITY DISORDERS USING AMINOSTEROLS
    Publication number: 20190194243
    Abstract: This invention relates to methods of stimulating the activity of the human and animal enteric nervous system. The method comprises orally administering an aminoserol, such as squalamine, a naturally occurring aminosterol isolated from Squalus acanthias, or derivatives thereof, to a subject in need.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 27, 2019
    Applicant: Enterin Laboratories, Inc.
    Inventor: Michael Zasloff
  • METHODS OF PREVENTING NEURODEVELOPMENTAL DISORDERS (AUTISM) USING AMINOSTEROLS
    Publication number: 20190185513
    Abstract: This invention relates to methods of stimulating the activity of the human and animal enteric nervous system. The method comprises orally administering an aminoserol, such as squalamine, a naturally occurring aminosterol isolated from Squalus acanthias, or derivatives thereof, to a subject in need.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 20, 2019
    Applicant: Enterin Laboratories, Inc.
    Inventor: Michael Zasloff
  • NEW SQUALAMINE SOLID FORMS AND METHODS OF MAKING THE SAME
    Publication number: 20190127416
    Abstract: Provided herein are crystalline solid forms of squalamine phosphate designated as Form 1 and Form 2, compositions containing one or both forms, and methods of their preparation and of their use.
    Type: Application
    Filed: October 26, 2018
    Publication date: May 2, 2019
    Applicant: Enterin, Inc.
    Inventors: Denise Barbut, Michael Zasloff
  • METHODS FOR TREATING SLEEP DISORDERS, SLEEP DISTURBANCES, AND RELATED SYMPTOMS USING AMINOSTEROL COMPOSITIONS
    Publication number: 20190091241
    Abstract: This invention relates to methods of treating or preventing a sleep disorder, sleep disturbance, or related symptom in a subject with aminosterols or pharmaceutically acceptable salts or derivatives thereof. In particular, the disclosed methods generally comprise administering an aminosterol to a subject in need, thereby stimulating an aminosterol-induced CNS response to treat and/or prevent a sleep disorder, sleep disturbance, or related symptom.
    Type: Application
    Filed: September 5, 2018
    Publication date: March 28, 2019
    Applicant: Enterin, Inc.
    Inventors: Denise Barbut, Michael Zasloff
  • Methods of treating and/or preventing neurodevelopmental disorders (autism) using aminosterols
    Patent number: 10208079
    Abstract: This invention relates to methods of stimulating the activity of the human and animal enteric nervous system. The method comprises orally administering an aminoserol, such as squalamine, a naturally occurring aminosterol isolated from Squalus acanthias, or derivatives thereof, to a subject in need.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: February 19, 2019
    Assignee: Enterin Laboratories, Inc.
    Inventor: Michael Zasloff
  • Methods of treating and/or preventing affective disorders of the nervous system (depression) using aminosterols
    Patent number: 10208080
    Abstract: This invention relates to methods of stimulating the activity of the human and animal enteric nervous system. The method comprises orally administering an aminoserol, such as squalamine, a naturally occurring aminosterol isolated from Squalus acanthias, or derivatives thereof, to a subject in need.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: February 19, 2019
    Assignee: Enterin Laboratories, Inc.
    Inventor: Michael Zasloff