Abstract: The disclosure relates to gradient delay time correction of magnetic resonance data. For recording the magnetic resonance data, use is made of a three-dimensional recording technique with linear recording trajectories oriented in different readout directions of a readout plane that is perpendicular to a partition direction. Calibration data is recorded which covers a plurality of partitions in partition direction and which describes readout-direction-dependent shifts, caused by delay effects, of measurement points, e.g. sampled k-space sections in the k-space. Correction data is determined by evaluating the calibration data, and the magnetic resonance data is corrected on the basis of the correction data in order to compensate for the delay effects. The calibration data, which covers a coverage region in partition direction, is recorded in a resolved manner in partition direction, and at least one acceleration technique is applied in the partition direction during the recording of the calibration data.

Abstract: An optical arrangement converts a laser beam into a line-type beam having a line-type beam cross-section that extends along a line direction with a non-vanishing intensity. The arrangement has: reshaping optics having: an input aperture through which the laser beam is radiated in; and an elongate output aperture, the reshaping optics being configured such that the laser beam radiated in is converted into a beam packet with beam segments that emerge through the output aperture; homogenization optics, which contribute to the conversion of the beam packet into the line-type output beam, and by which different beam segments are mixed and superposed along the line direction; and redirection optics configured to redirect the laser beam such that an incidence position/direction of laser beam on the input aperture is changed in dependence on time.

Abstract: A device for the treatment of fluid mixtures containing gases, such as in particular hydrogen, air, nitrogen or noble gases, and liquids, such as in particular ionic liquids, hydraulic oil or process liquids, having at least one separating stage (30) for separating the fluid mixture into a gas portion and a liquid portion, which, routed into a collection space (32), results in a float (44) rising, which, at a predeterminable liquid level in the collection space (32), actuates, without contact, a sensor device (42), which preferably actuates a discharge device for the purpose of draining the collection space (32), resulting in the lowering of the float (44), is characterized in that the outer circumference of the float (44) is guided axially displaceably along the inside of the housing wall (54) of the collection space (32), and in that the float (44) has at least one point of passage (50) for gas and/or liquid, which interconnects parts of the collection space (32) in a media-conveying manner, which parts are

Abstract: Provided herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof, useful as RIPK1 inhibitors, and pharmaceutical compositions comprising same. Further provided are methods of use and preparation. Also provided are methods of treating Ulcerative Colitis using a compound of Formula (I).

Abstract: Provided herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof, useful as RIPK1 inhibitors, and pharmaceutical compositions comprising same. Further provided are methods of use and preparation. Also provided are methods of treating Ulcerative Colitis using a compound of Formula (I).

Abstract: Provided herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof, useful as RIPK1 inhibitors, and pharmaceutical compositions comprising same. Further provided are methods of use and preparation. Also provided are methods of treating Ulcerative Colitis using a compound of Formula (I).

Abstract: A modular wound treatment system includes a central modular hub having a modular connection for one or more pneumatically-actuated, modular components, such as a pneumatically-actuated soft robotic gripper component configured to curve and at least partially encircle the wound when actuated and thereby apply direct pressure to the wound, and a pneumatically-actuated tourniquet component configured to apply pressure proximal to the wound to limit the flow of arterial blood to the wound. The system also includes a pressurized gas supply in pneumatic communication with the modular connection, sensors for measuring the amount of pressure being applied by the pneumatically-actuated, modular components, a display for providing system information, and a controller for controlling the system. Methods of treating a wounded subject using the system are also provided.

Abstract: A modular wound treatment system includes a central modular hub having a modular connection for one or more pneumatically-actuated, modular components, such as a pneumatically-actuated soft robotic gripper component configured to curve and at least partially encircle the wound when actuated and thereby apply direct pressure to the wound, and a pneumatically-actuated tourniquet component configured to apply pressure proximal to the wound to limit the flow of arterial blood to the wound. The system also includes a pressurized gas supply in pneumatic communication with the modular connection, sensors for measuring the amount of pressure being applied by the pneumatically-actuated, modular components, a display for providing system information, and a controller for controlling the system. Methods of treating a wounded subject using the system are also provided.

Abstract: The invention relates to an activation apparatus (20) for a galvanically decoupled direct voltage converter having a synchronous rectifier, comprising a signal generating device (22), which is designed to generate control signals (22c, 22d) for switch devices of the synchronous rectifier and a reference current signal (22b), a first comparator device (23), which is coupled to the signal generating device (22), and which is designed to detect the secondary-side output current (Jo) of the synchronous rectifier, compare it to the reference current signal (22b) and generate a current control signal in dependence on the comparison, and a pulse width modulation device (25), which is coupled to the signal generating device (22) and the first comparator device (23) and which is designed to generate pulse width modulated activation signals (25a) for the switch devices of the synchronous rectifier on the basis of the control signals (22c, 22d) and the current control signal, wherein the signal generating device (22) is

Abstract: The invention relates to an activation apparatus (20) for a galvanically decoupled direct voltage converter having a synchronous rectifier, comprising a signal generating device (22), which is designed to generate control signals (22c, 22d) for switch devices of the synchronous rectifier and a reference current signal (22b), a first comparator device (23), which is coupled to the signal generating device (22), and which is designed to detect the secondary-side output current (Jo) of the synchronous rectifier, compare it to the reference current signal (22b) and generate a current control signal in dependence on the comparison, and a pulse width modulation device (25), which is coupled to the signal generating device (22) and the first comparator device (23) and which is designed to generate pulse width modulated activation signals (25a) for the switch devices of the synchronous rectifier on the basis of the control signals (22c, 22d) and the current control signal, wherein the signal generating device (22) is

Abstract: A method for adjusting a loudness of an announcement sound signal relative to a loudness of an entertainment sound signal, the method including the steps of determining the loudness of the entertainment sound signal, and adjusting the loudness of the announcement sound signal relative to the entertainment sound signal by determining a self-adaptive gain offset of the announcement sound signal relative to the entertainment sound signal, the self-adaptive gain offset adapting to the auditory perception of a user to which the entertainment sound signal and the announcement sound signal are output.

Abstract: A method for adjusting a loudness of an announcement sound signal relative to a loudness of an entertainment sound signal, the method including the steps of determining the loudness of the entertainment sound signal, and adjusting the loudness of the announcement sound signal relative to the entertainment sound signal by determining a self-adaptive gain offset of the announcement sound signal relative to the entertainment sound signal, the self-adaptive gain offset adapting to the auditory perception of a user to which the entertainment sound signal and the announcement sound signal are output.

Abstract: A method and system for determining the position of a sound source in relation to a reference position, comprising the steps of generating a sound signal emitted from the sound source, detecting the emitted sound signal, processing the sound signal by the use of a physiological model of the ear, deducing at least one of lateral deviation in relation to the reference position, time delay of the sound signal from the sound source to the reference position, and the sound level of the detected sound signal.

Abstract: A system for processing credit applications. An adaptive decision engine produces a score determined by the risk associated with a credit application. The credit application is automatically approved or rejected if the score is above or below certain thresholds, and is otherwise referred for manual processing. The system may include a rules system that automatically approves applications if all conditions are met, and generates exceptions if all conditions are not met and refers the application to the adaptive decision engine for further processing. A decision to approve or reject an application may be based on a combination of the risk score and number of exceptions.

Abstract: A method and system for determining the position of a sound source in relation to a reference position, comprising the steps of generating a sound signal emitted from the sound source, detecting the emitted sound signal, processing the sound signal by the use of a physiological model of the ear, deducing at least one of lateral deviation in relation to the reference position, time delay of the sound signal from the sound source to the reference position, and the sound level of the detected sound signal.

Abstract: An audio decoding device for decompressing an audio signal that was compressed in accordance with a given compression method having a program-controlled signal processor which receives the compressed audio signal and from it produces a decompressed audio signal under the control of a decompression program; a loadable program memory that is connected to the signal processor for storing the decompression program; and a management device which is connected to the program memory and is controlled by the compressed audio signal, and which manages decompression programs corresponding to at least two different compression methods in order to determine the respectively used compression method from the compressed audio signal, to select the pertinent decompression program and to load the pertinent decompression program into the program memory.