Patents by Inventor Michaela Akermann

Michaela Akermann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acylated n-hydroxy methyl thalidomide prodrugs with immunomodulator action
    Patent number: 6417197
    Abstract: Thalidomide prodrugs of the formula I: in which R is —CHR1—NHR2 or —(CH2)nCOOH; R1 is H or C1-4 alkyl; R2 is H, C1-3 alkyl, C(O)—CH2—NHR3 or an amino-protective group, R3 is H or an amino-protective group, and n is an integer from 2 to 4, in the form of their free bases or of salts with physiologically acceptable acids, as well as a process for preparation of such prodrugs and the use of such prodrugs as an active drug substance.
    Type: Grant
    Filed: December 14, 1998
    Date of Patent: July 9, 2002
    Assignee: Gruenenthal GmbH
    Inventors: Johannes Schneider, Werner Winter, Stephan Wnendt, Kai Zwingenberger, Kurt Eger, Michaela Akermann