Patents by Inventor Michaela Frey

Michaela Frey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8454833
    Abstract: A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.
    Type: Grant
    Filed: November 16, 2011
    Date of Patent: June 4, 2013
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Nebojsa Nikolic, Michaela Frey, Wolfgang Grabmayer, Thomas Jancik, Matthias Fried, Klaus Tschetschkowitsch, Kurt Schnecker, Barbara Riegler, Alma Kasapovic
  • Publication number: 20120136139
    Abstract: A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.
    Type: Application
    Filed: November 16, 2011
    Publication date: May 31, 2012
    Applicants: BAXTER HEALTHCARE S.A., BAXTER INTERNATIONAL INC.
    Inventors: Nebojsa Nikolic, Michaela Frey, Wolfgang Grabmayer, Thomas Jancik, Matthias Fried, Klaus Tschetschkowitsch, Kurt Schnecker, Barbara Riegler, Alma Kasapovic
  • Patent number: 8075782
    Abstract: A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.
    Type: Grant
    Filed: August 20, 2010
    Date of Patent: December 13, 2011
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Nebojsa Nikolic, Michaela Frey, Wolfgang Grabmayer, Thomas Jancik, Matthias Fried, Klaus Tschetschkowitsch, Kurt Schnecker, Barbara Riegler, Alma Kasapovic
  • Patent number: 8075781
    Abstract: A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.
    Type: Grant
    Filed: August 20, 2010
    Date of Patent: December 13, 2011
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Nebojsa Nikolic, Michaela Frey, Wolfgang Grabmayer, Thomas Jancik, Matthias Fried, Klaus Tschetschkowitsch, Kurt Schnecker, Barbara Riegler, Alma Kasapovic
  • Patent number: 7959809
    Abstract: A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: June 14, 2011
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Nebojsa Nikolic, Michaela Frey, Wolfgang Grabmayer, Thomas Jancik, Matthias Fried, Klaus Tschetschkowitsch, Kurt Schnecker, Barbara Riegler, Alma Kasapovic
  • Publication number: 20100317081
    Abstract: A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.
    Type: Application
    Filed: August 20, 2010
    Publication date: December 16, 2010
    Applicants: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE S.A.
    Inventors: Nebojsa Nikolic, Michaela Frey, Wolfgang Grabmayer, Thomas Jancik, Matthias Fried, Klaus Tschetschkowitsch, Kurt Schnecker, Barbara Riegler, Alma Kasapovic
  • Publication number: 20100314317
    Abstract: A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.
    Type: Application
    Filed: August 20, 2010
    Publication date: December 16, 2010
    Applicants: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE S.A.
    Inventors: Nebojsa Nikolic, Michaela Frey, Wolfgang Grabmayer, Thomas Jancik, Matthias Fried, Klaus Tschetschkowitsch, Kurt Schnecker, Barbara Riegler, Alma Kasapovic
  • Publication number: 20090188862
    Abstract: A method is disclosed for filtering a protein in a liquid mixture in a manner that does not substantially damage or otherwise limit the recovery of the protein in the filtration filtrate. The method generally includes passing a liquid mixture containing a protein (e.g., an aqueous vWF mixture) through a filter while applying a counter pressure to the liquid mixture filtrate to accurately reduce and control the pressure differential across the filter. The disclosed method has the advantage that relatively high filtration flow rates can be achieved at relatively low pressure differentials, in contrast to high pressure differentials, which actually reduce the filtration flow rate of protein liquid mixtures. Further, the method can recover substantially all of the protein that is initially present in the liquid mixture.
    Type: Application
    Filed: December 22, 2008
    Publication date: July 30, 2009
    Applicants: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE S.A.
    Inventors: Nebojsa Nikolic, Michaela Frey, Wolfgang Grabmayer, Thomas Jancik, Matthias Fried, Klaus Tschetschkowitsch, Kurt Schnecker, Barbara Riegler, Alma Kasapovic
  • Publication number: 20080292495
    Abstract: The invention relates to a method for the continuous reduction of the odor pollution caused by the waste water in sewers, comprising the following steps: a) determining the actual pollution of the waste water by means of a water sample of the waste water, b) calculating the quantity of odor-reducing agent required to reduce the odor pollution below a defined threshold value, using the degree of pollution, c) adding the defined quantity of odor-reducing agent to the waste water, d) continuously repeating steps a) to c). The aim of the invention is to devise a device and a method of the above type for reliably detecting odor pollution and for reducing it to a minimum using the odor-reducing agents. For this purpose, in step a) the pollution of the waste water is determined by determining the pollution of the water sample with odorous substances.
    Type: Application
    Filed: June 9, 2008
    Publication date: November 27, 2008
    Applicant: Universitat Kassel
    Inventors: Franz-Bernd Frechen, Michaela Frey, Marco Ohme, Sebastian Grahlow