Patents by Inventor Michaela Oberle

Michaela Oberle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12584895
    Abstract: A method for evaluation of a thin-layer chromatography plate after performing a separation process that separates components of a sample on the thin-layer chromatography plate comprises a digitization step, wherein at least two digital images are taken that differ with respect to the wavelength range of illumination of the thin-layer chromatography plate. The method further comprises a position identification step wherein the position of the thin-layer chromatography plate is identified for each of the at least two digital images. Furthermore, the method comprises an evaluation step wherein an image information of the at least two digital images is superimposed for at least all regions with at least one visible spot within at least one of the at least two digital images, so that the superimposition of image information from identical regions of at least two digital images can be used for evaluation of the thin-layer chromatography.
    Type: Grant
    Filed: November 12, 2021
    Date of Patent: March 24, 2026
    Assignee: MERCK PATENT GMBH
    Inventors: Michaela Oberle, Eric Schunda, Robert Fischer
  • Publication number: 20240019409
    Abstract: A method for evaluation of a thin-layer chromatography plate after performing a separation process that separates components of a sample on the thin-layer chromatography plate comprises a digitization step, wherein at least two digital images are taken that differ with respect to the wavelength range of illumination of the thin-layer chromatography plate. The method further comprises a position identification step wherein the position of the thin-layer chromatography plate is identified for each of the at least two digital images. Furthermore, the method comprises an evaluation step wherein an image information of the at least two digital images is superimposed for at least all regions with at least one visible spot within at least one of the at least two digital images, so that the superimposition of image information from identical regions of at least two digital images can be used for evaluation of the thin-layer chromatography.
    Type: Application
    Filed: November 12, 2021
    Publication date: January 18, 2024
    Applicant: MERCK PATENT GMBH
    Inventors: Michaela OBERLE, Eric SCHUNDA, Robert FISCHER
  • Publication number: 20230417716
    Abstract: A thin-layer chromatography development chamber (1) that can be used for developing thin-layer chromatography plates (21) by introducing a liquid solvent onto a sample arranged on the surface of a thin-layer chromatography plate (21), whereby the solvent and the thin-layer chromatography plate (21) can be inserted into the development chamber (1), comprises a housing (2) with an opening (3). The opening (3) of the development chamber (1) can be closed with a cover (4) that comprises a data input unit (10) for entering or collecting data related to a development process performed within the development chamber (1). The cover (4) further comprises a data communication unit (16) that enables a wireless data transmission of the data related to the development process to a thin-layer chromatography data storage device (24).
    Type: Application
    Filed: November 12, 2021
    Publication date: December 28, 2023
    Applicant: MERCK PATENT GMBH
    Inventors: Michaela OBERLE, Eric SCHUNDA, Robert FISCHER
  • Patent number: 10578595
    Abstract: A method and device for the optical scanning of a chromatographic sample (3), where a sample plate (2) holding the sample (3) is illuminated with light from a first illumination device (13) and the light emitted by the sample plate (2) is detected by an optical detector device (15) which detects in cell form or area form, a second illumination device (14) is preferably firstly activated in a preparation step. The sample plate (2) is displaced in a first displacement direction relative to the detector device (15), illuminated by the first illumination device (13) and a first measurement image is recorded. The sample plate (2) is displaced in a second displacement direction relative to the detector device (15), illuminated by the second illumination device (14), and a second measurement image is recorded.
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: March 3, 2020
    Assignee: Merck Patent GmbH
    Inventors: Michael Schulz, Michaela Oberle, Thomas Ingendoh
  • Publication number: 20170336371
    Abstract: A method and device for the optical scanning of a chromatographic sample (3), where a sample plate (2) holding the sample (3) is illuminated with light from a first illumination device (13) and the light emitted by the sample plate (2) is detected by an optical detector device (15) which detects in cell form or area form, a second illumination device (14) is preferably firstly activated in a preparation step. The sample plate (2) is displaced in a first displacement direction relative to the detector device (15), illuminated by the first illumination device (13) and a first measurement image is recorded. The sample plate (2) is displaced in a second displacement direction relative to the detector device (15), illuminated by the second illumination device (14), and a second measurement image is recorded.
    Type: Application
    Filed: November 20, 2015
    Publication date: November 23, 2017
    Applicant: Merck Patent GmbH
    Inventors: Michael SCHULZ, Michaela OBERLE, Thomas INGENDOH
  • Patent number: 8702813
    Abstract: The invention relates to the use of specific ascorbic acid derivatives for dyeing keratin-containing fibers or as direct dyes for the preparation of a composition for dyeing keratin-containing fibers, and to methods for dyeing keratin-containing fibers, in particular for dyeing human hair.
    Type: Grant
    Filed: October 19, 2011
    Date of Patent: April 22, 2014
    Assignee: MERCK PATENT GmbH
    Inventors: Thomas Rudolph, Michaela Oberle
  • Publication number: 20130228192
    Abstract: The invention relates to the use of specific ascorbic acid derivatives for dyeing keratin-containing fibres or as direct dyes for the preparation of a composition for dyeing keratin-containing fibres, and to methods for dyeing keratin-containing fibres, in particular for dyeing human hair.
    Type: Application
    Filed: October 19, 2011
    Publication date: September 5, 2013
    Applicant: MERCK PATENT GMBH
    Inventors: Thomas Rudolph, Michaela Oberle
  • Patent number: 8293784
    Abstract: The invention relates to the use of ?-amino acid derivatives for improving the solubility of sparingly soluble substances in water or aqueous solutions, and to mixtures and preferred compositions.
    Type: Grant
    Filed: November 27, 2008
    Date of Patent: October 23, 2012
    Assignee: Merck Patent GmbH
    Inventors: Thomas Rudolph, Herwig Buchholz, Michaela Oberle
  • Publication number: 20110039924
    Abstract: The invention relates to the use of ?-amino acid derivatives for improving the solubility of poorly soluble substances in water or aqueous solutions and to mixtures and preferred preparations.
    Type: Application
    Filed: November 27, 2008
    Publication date: February 17, 2011
    Applicant: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Thomas Rudolph, Herwig Buchholz, Michaela Oberle
  • Patent number: D1103798
    Type: Grant
    Filed: December 1, 2022
    Date of Patent: December 2, 2025
    Assignee: Merck Patent GmbH
    Inventors: Andreas Ries, Dirk Einspänner, Monika Bäumle, Michaela Oberle, Mark Hinkle