Patents by Inventor Michal ABRAHAM KARNI

Michal ABRAHAM KARNI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SMALL MOLECULES FOR TREATING CANCER, INHIBITING CHEMOKINE ACTIVITY AND/OR INDUCING CELL DEATH
    Publication number: 20240002347
    Abstract: Compounds capable of, or usable in, inducing death of cancer cells and/or modulating a biological activity of a chemokine e.g., cell migration, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or in treating cancer, are provided herein. The compounds are collectively represented by Formulae Ia or Ib: wherein A, B, D, E, G and R1-R5 are as defined in the specification, with one or more of D, E and G, preferably E, is hydroxy.
    Type: Application
    Filed: September 19, 2023
    Publication date: January 4, 2024
    Applicant: AlonBio Ltd.
    Inventors: Amnon PELED, Michal ABRAHAM KARNI, Orly EIZENBERG
  • Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death
    Patent number: 11780814
    Abstract: Compounds capable of, or usable in, inducing death of cancer cells and/or modulating a biological activity of a chemokine e.g., cell migration, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or in treating cancer, are provided herein. The compounds are collectively represented by Formulae Ia or Ib: wherein A, B, D, E, G and R1-R5 are as defined in the specification, with one or more of D, E and G, preferably E, is hydroxy.
    Type: Grant
    Filed: January 27, 2022
    Date of Patent: October 10, 2023
    Assignee: AlonBio Ltd.
    Inventors: Amnon Peled, Michal Abraham Karni, Orly Eizenberg
  • SMALL MOLECULES FOR TREATING CANCER, INHIBITING CHEMOKINE ACTIVITY AND/OR INDUCING CELL DEATH
    Publication number: 20220144777
    Abstract: Compounds capable of, or usable in, inducing death of cancer cells and/or modulating a biological activity of a chemokine e.g., cell migration, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or in treating cancer, are provided herein. The compounds are collectively represented by Formulae Ia or Ib: wherein A, B, D, E, G and R1-R5 are as defined in the specification, with one or more of D, E and G, preferably E, is hydroxy.
    Type: Application
    Filed: January 27, 2022
    Publication date: May 12, 2022
    Applicant: Biokine Therapeutics Ltd.
    Inventors: Amnon PELED, Michal ABRAHAM KARNI, Orly EIZENBERG
  • Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death
    Patent number: 11261159
    Abstract: Compounds capable of, or usable in, inducing death of cancer cells and/or modulating a biological activity of a chemokine e.g., cell migration, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or in treating cancer, are provided herein. The compounds are collectively represented by Formulae Ia or Ib: wherein A, B, D, E, G and R1-R5 are as defined in the specification, with one or more of D, E and G, preferably E, is hydroxy.
    Type: Grant
    Filed: August 10, 2020
    Date of Patent: March 1, 2022
    Assignee: AlonBio Ltd.
    Inventors: Amnon Peled, Michal Abraham Karni, Orly Eizenberg
  • SMALL MOLECULES FOR INHIBITING CHEMOKINE ACTIVITY AND/OR CANCER CELLS GROWTH
    Publication number: 20220008407
    Abstract: Compounds capable of, or usable in, inducing death of cancer cells and/or modulating a biological activity of a chemokine e.g., cell migration, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or inhibiting a kinase and/or in treating a disease or disorder associated with an activity of a kinase, such as cancer and inflammatory diseases and disorders, are provided herein. The compounds are collectively represented by Formulae Ia or Ib: wherein A, B D, E, G and R1-R5 are as defined in the specification.
    Type: Application
    Filed: September 27, 2021
    Publication date: January 13, 2022
    Applicant: Biokine Therapeutics Ltd.
    Inventors: Amnon PELED, Michal ABRAHAM KARNI, Orly EIZENBERG
  • SMALL MOLECULES AGAINST CANCER
    Publication number: 20210228535
    Abstract: Compounds capable of, or usable in, killing cancer cells, and/or modulating a biological activity of a chemokine, and/or inhibiting a kinase, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or treating disease and disorders such as cancer and inflammatory diseases and disorders, are provided herein. The compounds are listed in Tables 2, 4 and 5, and/or are represented by Formulae I, IV, V and VI, as defined in the specification. Methods utilizing these compounds are also provided.
    Type: Application
    Filed: March 29, 2021
    Publication date: July 29, 2021
    Applicant: Biokine Therapeutics Ltd.
    Inventors: Amnon PELED, Michal ABRAHAM KARNI, Orly EIZENBERG
  • Small molecules against cancer
    Patent number: 10959979
    Abstract: Compounds capable of, or usable in, killing cancer cells, and/or modulating a biological activity of a chemokine, and/or inhibiting a kinase, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or treating disease and disorders such as cancer and inflammatory diseases and disorders, are provided herein. The compounds are listed in Tables 2, 4 and 5, and/or are represented by Formulae I, IV, V and VI, as defined in the specification. Methods utilizing these compounds are also provided.
    Type: Grant
    Filed: May 7, 2020
    Date of Patent: March 30, 2021
    Assignee: Biokine Therapeutics Ltd.
    Inventors: Amnon Peled, Michal Abraham Karni, Orly Eizenberg
  • SMALL MOLECULES FOR TREATING CANCER, INHIBITING CHEMOKINE ACTIVITY AND/OR INDUCING CELL DEATH
    Publication number: 20200369617
    Abstract: Compounds capable of, or usable in, inducing death of cancer cells and/or modulating a biological activity of a chemokine e.g., cell migration, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or in treating cancer, are provided herein. The compounds are collectively represented by Formulae Ia or Ib: wherein A, B, D, E, G and R1-R5 are as defined in the specification, with one or more of D, E and G, preferably E, is hydroxy.
    Type: Application
    Filed: August 10, 2020
    Publication date: November 26, 2020
    Applicant: Biokine Therapeutics Ltd.
    Inventors: Amnon PELED, Michal ABRAHAM KARNI, Orly EIZENBERG
  • SMALL MOLECULES AGAINST CANCER
    Publication number: 20200268709
    Abstract: Compounds capable of, or usable in, killing cancer cells, and/or modulating a biological activity of a chemokine, and/or inhibiting a kinase, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or treating disease and disorders such as cancer and inflammatory diseases and disorders, are provided herein. The compounds are listed in Tables 2, 4 and 5, and/or are represented by Formulae I, IV, V and VI, as defined in the specification. Methods utilizing these compounds are also provided.
    Type: Application
    Filed: May 7, 2020
    Publication date: August 27, 2020
    Applicant: Biokine Therapeutics Ltd.
    Inventors: Amnon PELED, Michal ABRAHAM KARNI, Orly EIZENBERG