Abstract: For partial volume correction, the partial volume effect is simulated using patient-specific segmentation. An organ or other object of the patient is segmented using anatomical imaging. For simulation, the locations of the patient-specific object or objects are sub-divided, creating artificial boundaries in the object. A test activity is assigned to each sub-division and forward projected. The difference of the forward projected activity to the test activity provides a location-by-location partial volume correction map. This correction map is used in reconstruction from the measured emissions, resulting in more accurate activity estimation with less partial volume effect.

Abstract: A system and method include acquisition of a set of tomographic images of a patient volume associated with each of a plurality of timepoints of a first radiopharmaceutical therapy cycle, determination, for each of the plurality of timepoints, of a systematic uncertainty for each of a plurality of regions within the patient volume based on the set of tomographic images associated with the timepoint, determination, for each of the plurality of timepoints, of a quantitative statistical uncertainty based on the set of tomographic images associated with the timepoint, determination of a dose and a dose uncertainty for each of the plurality of regions based on the set of tomographic images, the systematic uncertainty and the quantitative statistical uncertainty for each of the plurality of timepoints, and display of a cumulative dose and cumulative dose uncertainty for each of the plurality of regions based on the dose and the dose uncertainty determined for each of the plurality of regions.

Abstract: A set of first modality data is provided to an intra-reconstruction motion correction method. The set of first modality data includes a plurality of views. A set of second modality data is provided to the method. A motion estimate is generated for each of the plurality of views in the set of first modality data by registering the set of first modality data with the set of second modality data. A motion corrected model of the set of first modality data is generated by a forward projection including the motion estimate.

Abstract: A set of set of first modality data is received including at least one view comprising a plurality of gates. The set of first modality data is received from a first imaging modality of an imaging system. A set of second modality data is received from a second imaging modality of the imaging system. A motion corrected model of the set of first modality data is generated by forward projecting the set of first modality data including a motion estimate. An update factor for each of the plurality of views is generated by comparing at least one of the plurality of gates to the motion corrected model. The motion corrected model is updated by the update factor to generate a motion corrected image.

Abstract: For partial volume correction, the partial volume effect is simulated using patient-specific segmentation. An organ or other object of the patient is segmented using anatomical imaging. For simulation, the locations of the patient-specific object or objects are sub-divided, creating artificial boundaries in the object. A test activity is assigned to each sub-division and forward projected. The difference of the forward projected activity to the test activity provides a location-by-location partial volume correction map. This correction map is used in reconstruction from the measured emissions, resulting in more accurate activity estimation with less partial volume effect.

Abstract: A set of first modality data is provided to an intra-reconstruction motion correction method. The set of first modality data includes a plurality of views. A set of second modality data is provided to the method. A motion estimate is generated for each of the plurality of views in the set of first modality data by registering the set of first modality data with the set of second modality data. A motion corrected model of the set of first modality data is generated by a forward projection including the motion estimate.

Abstract: A set of set of first modality data is received including at least one view comprising a plurality of gates. The set of first modality data is received from a first imaging modality of an imaging system. A set of second modality data is received from a second imaging modality of the imaging system. A motion corrected model of the set of first modality data is generated by forward projecting the set of first modality data including a motion estimate. An update factor for each of the plurality of views is generated by comparing at least one of the plurality of gates to the motion corrected model. The motion corrected model is updated by the update factor to generate a motion corrected image.

Abstract: A method of clinical collaboration between a clinical site and an analysis site includes receiving scan data from a scanner via a first reconstruction computer system at the clinical site, implementing a reconstruction procedure on the received scan data using a second reconstruction computer system at the analysis site and configured in accordance with a reconstruction configuration parameter, the analysis site being remote from the clinical site, and transmitting data indicative of the reconstruction configuration parameter to the first reconstruction computer system to configure the first reconstruction computer system in accordance with the reconstruction configuration parameter.

Abstract: A method of clinical collaboration between a clinical site and an analysis site includes receiving scan data from a scanner via a first reconstruction computer system at the clinical site, implementing a reconstruction procedure on the received scan data using a second reconstruction computer system at the analysis site and configured in accordance with a reconstruction configuration parameter, the analysis site being remote from the clinical site, and transmitting data indicative of the reconstruction configuration parameter to the first reconstruction computer system to configure the first reconstruction computer system in accordance with the reconstruction configuration parameter.