Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for updating data of a map. One of the methods includes storing a map of an environment, the map comprising surfels and a road graph; receiving new surfel data for the surfels; adjusting the surfels based on the new surfel data; determining a vector field difference between the surfels of the stored map and the adjusted surfels; adjusting a portion of the road graph based on the vector field difference; generating an updated map comprising the adjusted surfels and the adjusted portion of the road graph; and storing the updated map.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for updating data of a map. One of the methods includes storing a map of an environment, the map comprising surfels and a road graph; receiving new surfel data for the surfels; adjusting the surfels based on the new surfel data; determining a vector field difference between the surfels of the stored map and the adjusted surfels; adjusting a portion of the road graph based on the vector field difference; generating an updated map comprising the adjusted surfels and the adjusted portion of the road graph; and storing the updated map.

Abstract: The present invention concerns methods and compositions involving inhibitors and of RAD51, a protein involved in homologous recombination. In some embodiments, there are methods for sensitizing cells to the effects of DNA damaging agents, which can have particular applications for cancer patients. In some embodiments of the invention, the RAD51 inhibitor is a small molecule that directly affects RAD51 activity, such as its ability to promote filament formation.

Abstract: The present disclosure includes systems and methods for off-the-record communication including expiring messages. An example method comprises receiving an electronic communication from a source device, the electronic communication including at least one expiring message, temporarily storing content of the expiring message in a non-durable memory for a predetermined amount of time, durably storing envelope information associated with the expiring message in a durable memory, and determining whether a recipient device for the expiring message is available to accept transmission of the expiring message and determining whether an expiration event has occurred.

Abstract: The present disclosure includes systems and methods for off-the-record communication including expiring messages. An example method comprises receiving an electronic communication from a source device, the electronic communication including at least one expiring message, temporarily storing content of the expiring message in a non-durable memory for a predetermined amount of time, durably storing envelope information associated with the expiring message in a durable memory, and determining whether a recipient device for the expiring message is available to accept transmission of the expiring message and determining whether an expiration event has occurred.

Abstract: The present disclosure includes systems and methods for off-the-record communication including expiring messages. An example method comprises receiving an electronic communication from a source device, the electronic communication including at least one expiring message, temporarily storing content of the expiring message in a non-durable memory for a predetermined amount of time, durably storing envelope information associated with the expiring message in a durable memory, and determining whether a recipient device for the expiring message is available to accept transmission of the expiring message and determining whether an expiration event has occurred.

Abstract: The invention is related to a portable electronic printing device equipped with a microprocessor, comprising a data processing module and a touch display designed for the user to communicate with the device and a printer module electronically connected and integrated in a single housing with the touch display equipped with a paper tray and an opening for paper output from the printer, characterised in that the opening designed for paper output from the printer (5) extends in parallel to the edge of the touch display (3) and is a located at a distance of not more than 80 mm from this edge, more preferably not more than 5 mm from this edge, and most preferably it is adjacent to this edge, wherein the housing of the said device has a back plane located opposite the touch display (3), the said plane being parallel to the surface of the touch display (3) at least in the part comprising the housing of the data processing module (2).

Abstract: The present disclosure includes systems and methods for off-the-record communication including expiring messages. An example method comprises receiving an electronic communication from a source device, the electronic communication including at least one expiring message, temporarily storing content of the expiring message in a non-durable memory for a predetermined amount of time, durably storing envelope information associated with the expiring message in a durable memory, and determining whether a recipient device for the expiring message is available to accept transmission of the expiring message and determining whether an expiration event has occurred.

Abstract: The invention is related to a portable electronic printing device equipped with a microprocessor, comprising a data processing module and a touch display designed for the user to communicate with the device and a printer module electronically connected and integrated in a single housing with the touch display equipped with a paper tray and an opening for paper output from the printer, characterised in that the opening designed for paper output from the printer (5) extends in parallel to the edge of the touch display (3) and is a located at a distance of not more than 80 mm from this edge, more preferably not more than 5 mm from this edge, and most preferably it is adjacent to this edge, wherein the housing of the said device has a back plane located opposite the touch display (3), the said plane being parallel to the surface of the touch display (3) at least in the part comprising the housing of the data processing module (2).

Abstract: The present invention relates to methods and compositions for modulating receptors in postsynaptic neurons of damaged or diseased retinas. The invention also related to methods for using the compositions set forth herein for treatment of diseases of hyperexcitability such as epilepsy.

Abstract: The present invention relates to methods and compositions for modulating receptors in postsynaptic neurons of damaged or diseased retinas. The invention also related to methods for using the compositions set forth herein for treatment of diseases of hyperexcitability such as epilepsy.

Abstract: The present disclosure includes systems and methods for off-the-record communication including expiring messages. An example method comprises receiving an electronic communication from a source device, the electronic communication including at least one expiring message, temporarily storing content of the expiring message in a non-durable memory for a predetermined amount of time, durably storing envelope information associated with the expiring message in a durable memory, and determining whether a recipient device for the expiring message is available to accept transmission of the expiring message and determining whether an expiration event has occurred.

Abstract: The present invention concerns methods and compositions involving inhibitors and of RAD51, a protein involved in homologous recombination. In some embodiments, there are methods for sensitizing cells to the effects of DNA damaging agents, which can have particular applications for cancer patients. In some embodiments of the invention, the RAD51 inhibitor is a small molecule that directly affects RAD51 activity, such as its ability to promote filament formation.

Abstract: The present disclosure includes systems and methods for off-the-record communication including expiring messages. An example method comprises receiving an electronic communication from a source device, the electronic communication including at least one expiring message, temporarily storing content of the expiring message in a non-durable memory for a predetermined amount of time, durably storing envelope information associated with the expiring message in a durable memory, and determining whether a recipient device for the expiring message is available to accept transmission of the expiring message and determining whether an expiration event has occurred.

Abstract: The present invention relates to methods and compositions for modulating receptors in postsynaptic neurons of damaged or diseased retinas. The invention also related to methods for using the compositions set forth herein for treatment of diseases of hyperexcitability such as epilepsy.