Abstract: Implantable devices disclosed herein may be configured to modulate the localized pH at an implantation site of the implantable device. By controlling, modulating, or otherwise adjusting the localized pH, various benefits can be achieved, such as controlling cell proliferation. The implantable device may include a body and one or more metallic features. Generally, the implantable device forms a galvanic cell such that a first metallic feature is configured to be preferentially oxidized to alter the localized pH environment in the vicinity of the implantable device.