Patents by Inventor Michal Shachar

Michal Shachar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pulse-medium perfusion bioreactor with improved mass transport for multiple-3-D cell constructs
    Patent number: 7608447
    Abstract: Disclosed is a novel net member for supporting one or more cell constructs in the culture chamber of a bioreactor, which comprises an array of impermeable pyramidal elements protruding from the face thereof, wherein each of the corners of the base of each of said impermeable pyramidal elements comprises a circular opening. This net member provides for uniform and unobstructed flow of culture medium through 3D cell constructs in culture. Also disclosed are a bioreactor and bioreactor system incorporating said net member. The bioreactor and bioreactor system may be used in the bioproduction of therapeutic proteins and stem cell expansion.
    Type: Grant
    Filed: December 9, 2004
    Date of Patent: October 27, 2009
    Assignee: Ben Gurion University of the Negev Research and Development Authority
    Inventors: Smadar Cohen, Tal Dvir, Michal Shachar
  • Pulse-medium perfusion bioreactor with improved mass transport for multiple-3-d cell constructs
    Publication number: 20070111310
    Abstract: Disclosed is a novel net member for supporting one or more cell constructs in the culture chamber of a bioreactor, which comprises an array of impermeable pyramidal elements protruding from the face thereof, wherein each of the corners of the base of each of said impermeable pyramidal elements comprises a circular opening. This net member provides for uniform and unobstructed flow of culture medium through 3D cell constructs in culture. Also disclosed are a bioreactor and bioreactor system incorporating said net member. The bioreactor and bioreactor system may be used in the bioproduction of therapeutic proteins and stem cell expansion.
    Type: Application
    Filed: December 9, 2004
    Publication date: May 17, 2007
    Inventors: Smadar Cohen, Tal Dvir, Michal Shachar