Abstract: A lateral flow test kit includes a cassette and a swab. The cassette comprises a vial of liquid closed by seal; a test strip; a passage leading from the exterior of the cassette to the vial; and a conduit communicating between the vial and the test strip. The swab can be inserted along the passage to cause a tip of the swab to enter the vial and release liquid from the vial. The liquid flows past a head of the swab to extract a sample and deliver it through the conduit 34 to the test strip. The passage may comprise an obstruction, which requires the user to push the swab past it with a force sufficient to penetrate the seal. The obstruction may also prevent removal of the used swab from the cassette. A distal end of the passage may be curved to deflect the tip of the swab towards the seal at a more favourable angle.

Abstract: A fixed dose injector pen is provided that includes a transmission element that is rotated to set and deliver a dose of a drug from a multi-dose cartridge. A circular ratchet defines a small number of engagement positions around its circumference and selectively transmits the rotation of the transmission element to a piston rod driver. The circular ratchet transmits the rotation of the transmission element to the piston rod driver only when the transmission element is rotated in a dose delivery direction, and only if the transmission element has previously been rotated in an opposite, dose setting direction through an angle sufficient to reach one of the engagement positions. An axially moving injector element can be used to drive rotation of the transmission element via a helical coupling. When the piston rod has advanced to a predetermined axial position, a last dose lock-out mechanism maintains the circular ratchet in engagement.

Abstract: A fixed dose injector pen comprises a transmission element 30 that is rotated to set and deliver a dose of a drug from a multi-dose cartridge 8. A circular ratchet 34 defines a small number of engagement positions around its circumference and selectively transmits the rotation of the transmission element 30 to a piston rod driver 24. Specifically, the circular ratchet 34 transmits the rotation of the transmission element 30 to the piston rod driver 24 only when the transmission element 30 is rotated in a dose delivery direction, and only if the transmission element 30 has previously been rotated in an opposite, dose setting direction through an angle sufficient to reach one of the engagement positions. Preferably, an axially moving injector element 4 is used to drive rotation of the transmission element 30 via a helical coupling 31, 32.