Patents by Inventor Michel Ashkar

Michel Ashkar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of warfarin sodium from warfarin acid
    Patent number: 6673944
    Abstract: The invention provides a method for the direct preparation of pure warfarin sodium from warfarin acid. The reaction is conducted in a polar organic solvent, preferably ethanol, using a volatilizable base, preferably sodium bicarbonate or sodium carbonate, at low temperature. Drying the final product is accomplished at low temperature to avoid decomposition of the final warfarin sodium product.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: January 6, 2004
    Assignee: Taro Pharmaceutical Industries, Ltd.
    Inventors: Michel Ashkar, Sorin Bercovici, Robert Graff
  • PREPARATION OF WARFARIN SODIUM FROM WARFARIN ACID
    Publication number: 20020120157
    Abstract: The invention provides a method for the direct preparation of pure warfarin sodium from warfarin acid. The reaction is conducted in a polar organic solvent, preferably ethanol, using a volatilizable base, preferably sodium bicarbonate or sodium carbonate, at low temperature. Drying the final product is accomplished at low temperature to avoid decomposition of the final warfarin sodium product.
    Type: Application
    Filed: February 28, 2001
    Publication date: August 29, 2002
    Inventors: Michel Ashkar, Sorin Bercovici, Robert Graff