Patents by Inventor Michel Azoulay

Michel Azoulay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR THE PREPARATION AND USE OF TOXIN CONJUGATES
    Publication number: 20090214438
    Abstract: The present invention relates to methods for the preparation of toxin conjugates that are useful in vaccination and other therapies and diagnostics. In particular, methods are provided that involve a [3+2] cycloaddition between a first reactive unsaturated group on a toxin moiety and a second reactive unsaturated group on a bioactive moiety. Also provided are conjugates that are formed through this conjugation method, pharmaceutical compositions comprising these conjugates, and methods of using these pharmaceutical compositions for the treatment or diagnostic of antigen-related conditions, including tumors and infections.
    Type: Application
    Filed: December 18, 2008
    Publication date: August 27, 2009
    Applicants: INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS
    Inventors: Ludger JOHANNES, Baldissera GIOVANI, Michel AZOULAY, Jean-Claude FLORENT
  • Prodrugs, their preparation and use as pharmaceuticals
    Patent number: 6146658
    Abstract: Glycosyl-spacer-drugs compounds (prodrugs), their preparation and their use as pharmaceuticals are described.
    Type: Grant
    Filed: May 20, 1997
    Date of Patent: November 14, 2000
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Klaus Bosslet, Jorg Czech, Dieter Hoffmann, Cenek Kolar, Fran.cedilla.ois Tillequin, Jean-Claude Florent, Michel Azoulay, Claude Monneret, Jean-Claude Jacquesy, Jean-Pierre Gesson, Michel Koch
  • Prodrugs their preparation and use as pharmaceuticals
    Patent number: 5955100
    Abstract: Glycosyl-spacer-drugs compounds (prodrugs), their preparation and their use as pharmaceuticals are described.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: September 21, 1999
    Assignees: Behringwerke Aktiengesellschaft, Laboratories Hoechst S/A
    Inventors: Klaus Bosslet, Jorg Czech, Dieter Hoffmann, Cenek Kolar, Fran.cedilla.ois Tillequin, Jean-Claude Florent, Michel Azoulay, Claude Monneret, Jean-Claude Jacquesy, Jean-Pierre Gesson, Michel Koch
  • Pro-prodrugs, their production and use
    Patent number: 5877158
    Abstract: Substrate-spacer-prodrug compounds (pro-prodrugs) suited for site specific delivery of drugs, a process of preparing them and their use are described.
    Type: Grant
    Filed: September 20, 1994
    Date of Patent: March 2, 1999
    Assignees: Behringwerke Aktiengesellschaft, Laboratoires Hoechst S/A
    Inventors: Klaus Bosslet, Jorg Czech, Dieter Hoffmann, Fran.cedilla.ois Tillequin, Jean-Claude Florent, Michel Azoulay, Claude Monneret, Jean-Claude Jacquesy, Jean-Pierre Gesson, Michel Koch
  • Prodrugs for enzyme mediated activation
    Patent number: 5621002
    Abstract: Enzymatically clearable prodrugs with reduced Michaelis-Menten constant (Km) are described.
    Type: Grant
    Filed: September 9, 1994
    Date of Patent: April 15, 1997
    Assignees: Behringwerke Aktiengesellschaft, Laboratoires Hoechst S/A
    Inventors: Klaus Bosslet, J org Czech, Dieter Hoffmann, Andrea Vasella, Roland Hoos, Fran.cedilla.ois Tillequin, Jean-Claude Florent, Michel Azoulay, Claude Monneret, Jean-Claude Jacquesy, Jean-Pierre Gesson, Michel Koch
  • Toilet
    Patent number: D681786
    Type: Grant
    Filed: December 2, 2011
    Date of Patent: May 7, 2013
    Inventor: Michel Azoulay