Abstract: The present invention relates to a solid pharmaceutical composition comprising a solid dispersion containing at least one active principle and a pharmaceutically acceptable polymer matrix, a characterized in that said pharmaceutically acceptable polymer matrix comprises a blend of (i) polydextrose, in the form of a continuous polydextrose phase, in order to promote the disintegration of the composition in an aqueous medium, and (ii) at least one polymer other than polydextrose, in the form of a continuous phase of this polymer, whereby the polydextrose is in a concentration of at least 20 wt % and the at least one polymer other than polydextrose is in a concentration of at least 20 wt % in relation to the total weight of said pharmaceutically acceptable polymer matrix.

Abstract: The present invention relates to a solid pharmaceutical composition comprising a solid dispersion containing at least one active principle and a pharmaceutically acceptable polymer matrix, a characterized in that said pharmaceutically acceptable polymer matrix comprises a blend of (i) polydextrose, in the form of a continuous polydextrose phase, in order to promote the disintegration of the composition in an aqueous medium, and (ii) at least one polymer other than polydextrose, in the form of a continuous phase of this polymer, whereby the polydextrose is in a concentration of at least 20 wt % and the at least one polymer other than polydextrose is in a concentration of at least 20 wt % in relation to the total weight of said pharmaceutically acceptable polymer matrix.

Abstract: A device for spraying or dispensing a fluid or powdery product on a surface to be treated and/or an intake element (50), comprising: a dispensing member (1), including a dispensing opening (31), the dispensing member being associated with a reservoir (2) containing the product and being movable between an inoperative position and a dispensing position; and an actuating device for moving the dispensing member (1) towards its dispensing position for delivering a dose of product: The device further comprises: a device for measuring distance (20) movable between an inoperative position and their useful position, and arranged in their useful position such that each time the device is used the dispensing opening (31) is located at a fixed predetermined distance from the surface to be treated and/or the intake element (50), the movement of the distance measuring device (20) from their useful position towards their inoperative position bringing the dispensing member (1) back towards its inoperative position.