Patents by Inventor Michel Biard

Michel Biard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-butyl-3-(4-[3(dibutylamino)propoxy]benzoyl)-5-nitro-benzofuran hydrochloride and preparation thereof
    Patent number: 6846936
    Abstract: The invention relates to 2-butyl-3-(4-[3-(dibutylamino)propoxy]benzoyl-5-nitrobenzofuran hydrochloride, to its preparation and to its use as synthetic intermediate, in particular in preparing 2-butyl-3-(4-[3-(dibutylamino)propoxy]benzoyl)-5-nitrobenzofuran, itself an intermediate for dronedarone.
    Type: Grant
    Filed: December 10, 2001
    Date of Patent: January 25, 2005
    Assignee: Sanofi-Synthelabo
    Inventor: Michel Biard
  • 2-butyl-3-(4-[3(dibutylamino)propoxy]benzoyl)-5-nitro-benzofuran hydrochloride and preparation thereof
    Publication number: 20040010032
    Abstract: The invention relates to 2-butyl-3-(4-[3-(dibutylamino)propoxy]benzoyl-5-nitrobenzofuran hydrochloride, to its preparation and to its use as synthetic intermediate, in particular in preparing 2-butyl-3-(4-[3-(dibutylamino)propoxy]benzoyl)-5-nitrobenzofuran, itself an intermediate for dronedarone.
    Type: Application
    Filed: June 4, 2003
    Publication date: January 15, 2004
    Inventor: Michel Biard
  • Method for preparing a thiopene derivative
    Patent number: 6639083
    Abstract: The invention relates to a process for preparing 2-thienyl-2-ethanol, in which: a) thiophene is metallated using an alkali metal, in the presence of an electron transfer agent, b) the compound obtained is treated with ethylene oxide, c) the thienyl derivative thus formed is hydrolyzed, to give the desired compound. 2-Thienyl-2-ethanol is a synthetic intermediate.
    Type: Grant
    Filed: April 19, 2002
    Date of Patent: October 28, 2003
    Assignee: Sanofi-Synthelabo
    Inventors: Michel Biard, André Bousquet
  • Method for preparing bromomenthyl-biphenyl derivatives
    Patent number: 6214999
    Abstract: The present invention relates to a process for the preparation of 4′-bromomethyl-biphenyl derivatives of the formula: by reacting a 4′-methyl-biphenyl derivative of the formula: with a brominating agent a in a hydrobromic acid/alkali metal bromate system in a two-phase medium, and under photo-iradiation, where R is as defined in the specification.
    Type: Grant
    Filed: July 14, 2000
    Date of Patent: April 10, 2001
    Assignee: Sanofi-Synthelabo
    Inventors: Michel Biard, Bertrand Castro