Patents by Inventor Michel Brahic

Michel Brahic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Infectious cDNA of an approved vaccine strain of measles virus, use for immunogenic compositions
    Patent number: 9701944
    Abstract: The invention relates to a cDNA molecule which encodes the nucleotide sequence of the full length antigenomic (+)RNA strand of a measles virus (MV) originating from an approved vaccine strain. It also concerns the preparation of immunogenic compositions using said cDNA.
    Type: Grant
    Filed: March 24, 2015
    Date of Patent: July 11, 2017
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique
    Inventors: Frederic Tangy, Chantal Combredet, Valerie Labrousse-Najburg, Michel Brahic
  • INFECTIOUS CDNA OF AN APPROVED VACCINE STRAIN OF MEASLES VIRUS, USE FOR IMMUNOGENIC COMPOSITIONS
    Publication number: 20150275184
    Abstract: The invention relates to a cDNA molecule which encodes the nucleotide sequence of the full length antigenomic (+)RNA strand of a measles virus (MV) originating from an approved vaccine strain. It also concerns the preparation of immunogenic compositions using said cDNA.
    Type: Application
    Filed: March 24, 2015
    Publication date: October 1, 2015
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT PASTEUR
    Inventors: Frederic TANGY, Chantal COMBREDET, Valerie LABROUSSE-NAJBURG, Michel BRAHIC
  • Infectious cDNA of an approved vaccine strain of measles virus, use for immunogenic compositions
    Patent number: 9005925
    Abstract: The invention relates to a cDNA molecule which encodes the nucleotide sequence of the full length antigenomic (+)RNA strand of a measles virus (MV) originating from an approved vaccine strain. It also contains the preparation of immunogenic compositions using said cDNA.
    Type: Grant
    Filed: July 24, 2008
    Date of Patent: April 14, 2015
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique
    Inventors: Frédéric Tangy, Chantal Combredet, Valérie Labrousse-Najburg, Michel Brahic
  • Infectious cDNA of an approved vaccine strain of measles virus, use for immunogenic compositions
    Patent number: 9005961
    Abstract: The invention relates to a cDNA molecule which encodes the nucleotide sequence of the full length antigenomic (+)RNA strand of a measles virus (MV) originating from an approved vaccine strain, for example, the Schwarz strain. It also concerns the preparation of infectious recombinant viruses and immunogenic compositions using the cDNA.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: April 14, 2015
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique
    Inventors: Fréderic Tangy, Chantal Combredet, Valérie Labrousse-Najburg, Michel Brahic
  • IMMUNOMODULATION BY CONTROLLING INTERFERON-GAMMA LEVELS WITH THE LONG NON-CODING RNA NeST
    Publication number: 20140056929
    Abstract: Compositions and methods of modulating an immune response by controlling levels of interferon-gamma (IFN-?) production by leukocytes are disclosed. Adjustment of IFN-? levels is achieved by increasing or decreasing the activity of NeST (nettoie Salmonella pas Theiler's [cleanup Salmonella not Theiler's]), a long non-coding RNA that induces expression of IFN-?. In particular, the invention relates to the use of NeST and inhibitors of NeST to modulate levels of IFN-? for treatment of inflammatory conditions, autoimmune diseases, infectious diseases, immunodeficiency, and cancer.
    Type: Application
    Filed: August 23, 2013
    Publication date: February 27, 2014
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Karla A. Kirkegaard, Michel Brahic, J. Antonio Gomez, Howard Yuan-Hao Chang
  • Infectious cDNA of an approved vaccine strain of measles virus, use for immunogenic compositions
    Publication number: 20130296541
    Abstract: The invention relates to a cDNA molecule which encodes the nucleotide sequence of the full length antigenomic (+)RNA strand of a measles virus (MV) originating from an approved vaccine strain. It also contains the preparation of immunogenic compositions using said cDNA.
    Type: Application
    Filed: July 24, 2008
    Publication date: November 7, 2013
    Inventors: Frederic Tangy, Chantal Combredet, Valerie Labrousse-Najburg, Michel Brahic
  • Infectious cDNA of an approved vaccine strain of measles virus, use for immunogenic compositions
    Publication number: 20050227224
    Abstract: The invention relates to a cDNA molecule which encodes the nucleotide sequence of the full length antigenomic (+)RNA strand of a measles virus (MV) originating from an approved vaccine strain. It also concerns the preparation of immunogenic compositions using said cDNA.
    Type: Application
    Filed: December 17, 2004
    Publication date: October 13, 2005
    Inventors: Frederic Tangy, Chantal Combredet, Valerie Labrousse-Najburg, Michel Brahic