Patents by Inventor Michel Colin

Michel Colin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5289465
    Abstract: A method of data transmission over an internal bus of a workstation, effecting communication of an interface coupler and a telephone line and devices adapted for various communication functions. The method employs the synchronization signal of a voice network to define 125-microsecond communication frames. Included in each 125-microsecond frame thus defined are a maximum of eight variable-length subframes corresponding to a maximum of eight devices. The first two bytes of each subframe are header bytes. Coded in the header bytes of each subframe are a device destination address, and length codes indicating the number of bytes of data included in the subframe and the number of active bits in the last byte.
    Type: Grant
    Filed: August 10, 1992
    Date of Patent: February 22, 1994
    Assignee: Bull S.A.
    Inventors: Alain Mouro, Michel Colin
  • Patent number: 5268494
    Abstract: Compounds corresponding to the formula: ##STR1## wherein A represents --CH.sub.2).sub.2 or --C.tbd.C--;n is equal to 0, 1 or 2;R represents hydroxyl, alkoxy having the formula --OR.sub.1, or amino having the formula ##STR2## R.sub.1 represents alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl or aralkyl;R.sub.2 and R.sub.3 represent hydrogen, alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl or benzyl;R.sub.2 and R.sub.3 form, with the nitrogen atom, a heterocyclic ring.Application of these compounds in pharmacy and cosmetics.
    Type: Grant
    Filed: June 4, 1992
    Date of Patent: December 7, 1993
    Assignee: Centre International de Recherches Dermatologiques C.I.R.D.
    Inventors: Braham Shroot, Christopher Hensby, Jean Maignan, Gerard Lang, Michel Colin
  • Patent number: 5151534
    Abstract: Compounds corresponding to the formula: ##STR1## wherein A represents --(CH.sub.2).sub.2 or --(C.tbd.C)--;n is equal to 0, 1 or 2;R represents hydroxyl, alkoxy having the formula --OR.sub.1, or amino having the formula ##STR2## R.sub.1 represents alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl or aralkyl;R.sub.2 and R.sub.3 represent hydrogen, alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl or benzyl;R.sub.2 and R.sub.3 form, with the nitrogen atom, a heterocyclic ring.Application of these compounds in pharmacy and cosmetics.
    Type: Grant
    Filed: May 10, 1989
    Date of Patent: September 29, 1992
    Assignee: Centre International de Recherches Dermatologiques (CIRD)
    Inventors: Braham Shroot, Christopher Hensby, Jean Maignan, Gerard Lang, Michel Colin
  • Patent number: 5066427
    Abstract: Compound, corresponding to the formulaC.sub.8 H.sub.17 (C.tbd.C--CH.sub.2).sub.3 CH.sub.2 CH.sub.2 COR (I)in which R is a C.sub.1 -C.sub.8 lower alkoxy or C.sub.4 -C.sub.6 cycloaly group, substituted with one or more hydroxyl groups and/or interrupted by one or more hetero atoms chosen from oxygen and sulphur, an amino group of structure ##STR1## in which R.sub.1 or R.sub.2, which may be identical or different, denote a hydrogen atom or a linear or branched C.sub.1 -C.sub.8 lower alkyl radical, optionally interrupted by one or more hetero atoms chosen from oxygen, sulphur and nitrogen, this alkyl radical being able to be substituted with one or more hydroxyl groups, R.sub.1 and R.sub.2 not being able to denote hydrogen simultaneously, or alternatively R.sub.1 and R.sub.2 form, together with the nitrogen atom, a heterocyclic system optionally containing oxygen, sulphur or nitrogen as an additional hetero atom, one of the radicals R.sub.1 and R.sub.
    Type: Grant
    Filed: September 22, 1989
    Date of Patent: November 19, 1991
    Assignee: Centre International de Recherches Dermatologiques dite CIRD
    Inventors: Braham Shroot, Christopher Hensby, Jean Maignan, Gerard Lang, Serge Restle, Michel Colin
  • Patent number: 4924012
    Abstract: Process for preparing derivatives of baccatine III and of 10-deacetylbaccatine III, of general formula (I), in which R is hydrogen or acetyl, by condensation of an acid of general formula (II) with a derivative of baccatine III or of 10-deacetylbaccatine III of general formula (III), R.sub.1, R.sub.2 and R.sub.3 denoting hydroxy-protecting groups, followed by the replacement of the protecting groups by hydrogen.
    Type: Grant
    Filed: April 3, 1989
    Date of Patent: May 8, 1990
    Assignee: Rhone-Poulenc Sante
    Inventors: Michel Colin, Daniel Guenard, Francoise Gueritte-Voegelein, Pierre Potier
  • Patent number: 4916136
    Abstract: Compound, characterized in that it corresponds to the formula:C.sub.5 H.sub.11 (C.tbd.C--CH.sub.2).sub.4 --CH.sub.2 CH.sub.2 CO R (I)in which R is an amino group of structure ##STR1## in which R.sub.1 and R.sub.2, which may be identical or different, denote a hydrogen atom or a linear or branches C.sub.1 -C.sub.8 lower alkyl radical substituted with at least one hydroxyl group, it being possible for this C.sub.1 -C.sub.8 lower alkyl radical to be interrupted by one or more hetero atoms chosen from oxygen, nitrogen or sulphur, R.sub.1 and R.sub.2 not simultaneously denoting a hydrogen atom and it being possible for R.sub.1 and R.sub.
    Type: Grant
    Filed: December 28, 1987
    Date of Patent: April 10, 1990
    Assignee: Centre International de Recherches Dermatologioues C.I.R.D.
    Inventors: Braham Shroot, Christopher Hensby, Jean Maignan, Gerard Lang, Serge Restle, Michel Colin
  • Patent number: 4889865
    Abstract: Mono, di and tri-esters of 1,8-dihydroxy-10-phenyl-9-anthrone or -9-anthranol have the formula ##STR1## wherein p is 0 or 1,(a) when p=0, t=1 and R.sub.2 represents hydrogen or --COR.sub.3,(b) when p=1, t=0 and R.sub.1 and R.sub.2 each independently represent hydrogen or --COR.sub.3,R.sub.3 represents linear or branched alkyl having 1-17 carbon atoms, cycloalkyl, phenyl or phenyl substituted by lower alkyl, lower alkoxy, halogen, a nitro function, --CF.sub.3 or a hydroxyl function, and mixtures of said esters. These esters are prepared by reacting 1,8-dihydroxy-10-phenyl-9-anthrone with an activated form of an acid. The esters are useful in human or veterinary medicine and in cosmetic compositions.
    Type: Grant
    Filed: February 21, 1989
    Date of Patent: December 26, 1989
    Assignee: Centre International de Recherches Dermatologiques C.I.R.D.
    Inventors: Braham Shroot, Gerard Lang, Jean Maignan, Serge Restle, Christopher Hensby, Michel Colin
  • Patent number: 4877789
    Abstract: Compound, corresponding to the formulaC.sub.8 H.sub.17 --(C.tbd.C--CH.sub.2).sub.3 --CH.sub.2 CH.sub.2 CH.sub.2 R O (I)in which R is a C.sub.1 -C.sub.8 lower alkoxy or C.sub.4 -C.sub.6 cycloalkoxy group, substituted with one or more hydroxyl groups and/or interrupted by one or more hetero atoms chosen from oxygen and sulphur, an amino group of structure ##STR1## in which R.sub.1 or R.sub.2, which may be identical or different, denote a hydrogen atom or a linear or branched C.sub.1 -C.sub.8 lower alkyl radical, optionally interrupted by one or more hetero atoms chosen from oxygen, sulphur and nitrogen, this alkyl radical being able to be substituted with one or more hydroxyl groups, R.sub.1 and R.sub.2 not being able to denote hydrogen simultaneously, or alternatively R.sub.1 and R.sub.2 form, together with the nitrogen atom, a heterocyclic system optionally containing oxygen, sulphur or nitrogen as an additional hetero atom, one of the radicals R.sub.1 and R.sub.
    Type: Grant
    Filed: July 3, 1986
    Date of Patent: October 31, 1989
    Assignee: Centre International de Recherches Dermatologiques dite C.I.R.D.
    Inventors: Braham Shroot, Christopher Hensby, Jean Maignan, Gerard Lang, Serge Restle, Michel Colin
  • Patent number: 4857653
    Abstract: Taxol and 10-deacetyltaxol are prepared from a compound of formula: ##STR1## in which R' represents acetyl or 2,2,2-trichloroethoxycarbonyl radical, by removal of the t-butoxycarbonyl radical, benzoylation of the amine product obtained, and removal of the 2,2,2-trichloroethoxycarbonyl group(s).
    Type: Grant
    Filed: July 14, 1987
    Date of Patent: August 15, 1989
    Assignee: Rhone-Poulenc Sante
    Inventors: Michel Colin, Daniel Guenard, Francoise Gueritte-Voegelein, Pierre Potier
  • Patent number: 4851541
    Abstract: A process for preparing a 4,5-tri or tetramethylene-4-isothiazoline-3-one comprises cyclizing a 2-alkyl or aralkyl thio-1-cycloalkene-1-carboxamide in the form of its sulfoxide in an organic solvent in the presence of a acid chloride and adding to the resulting 4,5-tri or tetramethylene-4-isothiazoline-3-one hydrochloride a mineral or organic base or water so as to free the 4,5-tri or tetramethylene-4-isothiazoline-3-one in the form of a free base.
    Type: Grant
    Filed: June 5, 1986
    Date of Patent: July 25, 1989
    Assignee: Centre International de Recherches Dermatologiques (C.I.R.D.)
    Inventors: Jean Maignan, Serge Restle, Michel Colin
  • Patent number: 4843097
    Abstract: Mono, di and tri-esters of 1,8-dihydroxy-10-phenyl-9-anthrone or -9-anthranol have the formula ##STR1## wherein p is 0 or 1,(a) when p=0, t=1 and R.sub.2 represents hydrogen or --COR.sub.3,(b) when p=1, t=0 and R.sub.1 and R.sub.2 each independently represent hydrogen or --COR.sub.3,R.sub.3 represents linear or branched alkyl having 1-17 carbon atoms, cycloalkyl, phenyl or phenyl substituted by lower alkyl, lower alkoxy, halogen, a nitro function, --CF.sub.3 or a hydroxyl function, and mixtures of said esters. These esters are prepared by reacting 1,8-dihydroxy-10-phenyl-9-anthrone with an activated form of an acid. The esters are useful in human or veterinary medicine and in cosmetic compositions.
    Type: Grant
    Filed: April 4, 1988
    Date of Patent: June 27, 1989
    Assignee: Groupement d'Interet Economique dit: Centre International de Recherches Dermatologiques C.I.R.D.
    Inventors: Braham Shroot, Gerard Lang, Jean Maignan, Serge Restle, Christopher Hensby, Michel Colin
  • Patent number: 4814470
    Abstract: Taxol derivatives of formula ##STR1## in which R represents hydrogen or acetyl, one of R.sub.1 or R.sub.2 represents hydroxy and the other represents tert-butoxycarbonylamino and their isomers are useful antitumor agents.
    Type: Grant
    Filed: July 14, 1987
    Date of Patent: March 21, 1989
    Assignee: Rhone-Poulenc Sante
    Inventors: Michel Colin, Daniel Guenard, Francoise Gueritte-Voegelein, Pierre Potier
  • Patent number: 4654354
    Abstract: The invention provides compounds of formula ##STR1## in which formula R.sub.1 and R.sub.2 are identical or different and denote:(1) taken separately: a hydrogen atom, a linear or branched C.sub.1 -C.sub.4 alkyl radical, an unsubstituted phenyl radical or a phenyl radical substituted with a halogen atom, with a C.sub.1 -C.sub.4 alkoxy radical or with a C.sub.1 -C.sub.4 alkoxy radical;(2) taken together either(a) a polymethylene linkage; or(b) a benzene ring; or(c) a cyclic linkage containing a nitrogen atom to constitute an isothiazolopyridinone derivative; m being able to have the values 0 or 1;the group A in the formula (IV) denoting the group ##STR2## where R.sub.8 corresponds to a hydrogen atom, a methyl radical, a hydroxymethyl radical or a --CH.sub.2 O--CO--Ret group. The invention also provides a process for preparing the abovementioned compounds and also drug compositions and cosmetic compositions containing them.
    Type: Grant
    Filed: September 23, 1985
    Date of Patent: March 31, 1987
    Assignee: Centre International De Recherches Dermatologiques (C.I.R.D.)
    Inventors: Braham Shroot, Gerard Lang, Jean Maignan, Michel Colin
  • Patent number: 4111554
    Abstract: An improved flame photometry detector to give direct quantitative detection of molecules containing sulfur by:-- the total combustion of the mixture to be analyzed so as to transform the sulfur into sulfur oxide (primarily SO.sub.2);-- the linearization, by an electronic device, of the signal supplied by the electrometer, in series with the photomultiplier of the detector, prior to recording (this results in the proportionality of the recording to the number of sulfur-containing molecules detected); and preferably the provision of a leakage flow beyond the burner and in front of the detection so as to avoid saturation of the detector.These improvements can be applied to the analysis of a hydrocarbon mixture and of sulfur compounds which have been previously eluted on a chromatographic column.
    Type: Grant
    Filed: February 17, 1976
    Date of Patent: September 5, 1978
    Assignee: Compagnie Francaise de Raffinage
    Inventors: Jean-Michel Colin, Dominique Herouard
  • Patent number: 4080465
    Abstract: A method for improving the appearance of the greasy skin of the face of a person having a skin so characterized, which comprises topically applying to the skin of the face an effective amount of a composition containing as an active ingredient a cis or trans 3,4-thiolannediol, its cis or trans S-oxide derivatives or its cis or trans S-dioxide derivatives.
    Type: Grant
    Filed: January 27, 1976
    Date of Patent: March 21, 1978
    Assignee: Societe Anonyme dite: L'Oreal
    Inventors: Claude Bouillon, Michel Colin
  • Patent number: 3950532
    Abstract: A composition and method for treating the hair and skin characterized by a greasy, unaesthetic appearance to reduce or essentially eliminate this greasy appearance which includes topically applying to a human having hair or skin so characterized a cosmetic composition containing as an active ingredient a cis or trans 3,4-thiolannediol, its cis or trans S-oxide derivatives or its cis or trans S-dioxide derivatives.
    Type: Grant
    Filed: May 10, 1972
    Date of Patent: April 13, 1976
    Assignee: L'Oreal
    Inventors: Claude Bouillon, Michel Colin