Patents by Inventor Michel De Wilde

Michel De Wilde has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7780386
    Abstract: A coupling mechanism is provided. The coupling mechanism includes a bushing assembly adapted to establish a coupling when rotated, a housing that is rotatable when torque is applied to the housing, a torque-limit member positioned between the housing and the bushing assembly such that when the torque-limit member is in a positive-lock state, the housing and bushing assembly rotate jointly upon the application of torque until a predefined torque level is attained. A compressible member is included that engages the torque-limit member to define through frictional resistance of moving parts and parts geometry a predefined torque level. The torque-limit member switches from the positive-lock state to a ratchet state when the predefined torque level is attained. When the torque-limit member is in the ratchet state, the housing rotates relative to the bushing assembly.
    Type: Grant
    Filed: August 25, 2004
    Date of Patent: August 24, 2010
    Inventors: Michael Robert Lau, Eric Michel De Wild
  • Patent number: 6169171
    Abstract: Isolated DNA sequences encoding a novel hybrid protein are provided which comprise a portion of the CS protein of P. falciparum and the surface antigen of Hepatitis B virus. Vectors and host cells containing the isolated DNA sequences are also disclosed.
    Type: Grant
    Filed: September 18, 1997
    Date of Patent: January 2, 2001
    Assignee: SmithKline Beecham Biologicals (s.a.)
    Inventors: Michel De Wilde, Joseph Cohen
  • Patent number: 5928902
    Abstract: A novel hybrid protein is provided which comprises a portion of the CS protein of P. falciparum and the surface antigen of Hepatitis B virus. The use of this protein for vaccination purposes is disclosed.
    Type: Grant
    Filed: December 4, 1996
    Date of Patent: July 27, 1999
    Assignee: SmithKline Beecham Biologicals (s.a.)
    Inventors: Michel De Wilde, Joseph Cohen
  • Patent number: 4666837
    Abstract: DNA sequences and recombinant DNA molecules comprising at least a portion coding for all or part of subunits A and/or B of cholera toxin are prepared by enzymatic digestion of DNA of V. cholerae strains, isolating specific fragments and inserting them in appropriate vectors and subunits A and/or B of cholera toxin are prepared by culture of microorganisms containing said modified vectors.
    Type: Grant
    Filed: May 24, 1982
    Date of Patent: May 19, 1987
    Assignee: SmithKline-RIT
    Inventors: Nigel Harford, Michel De Wilde