Patents by Inventor Michel Dubois

Michel Dubois has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240138740
    Abstract: A method for detecting a representative cardiac activity includes the arrangement of a plurality of electrodes, the measurement of the value of electrophysiological descriptors, and the calculation (CALC) of a score.
    Type: Application
    Filed: March 25, 2022
    Publication date: May 2, 2024
    Inventors: Laura BEAR, Olivier BERNUS, Rémi DUBOIS, Michel HAISSAGUERRE, Nolwenn TAN
  • Patent number: 11866829
    Abstract: A gas wiping device for controlling a thickness of a coating layer deposited on a running metal strip plated with molten metal in an industrial hot-dip installation includes: a main nozzle unit and a secondary nozzle unit, for blowing a wiping jet on a surface of the running strip, the main nozzle unit and secondary nozzle unit respectively including a main and secondary chamber fed by pressurized non-oxidizing gas and at least a main and secondary elongated nozzle slot formed in a tip of the respective main and secondary nozzle units, the tips each including an external top side, facing a downstream side of the running strip, and making an angle with the surface of the running strip. The secondary nozzle unit is adjacent the main nozzle unit over an external top side of the main nozzle unit tip.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: January 9, 2024
    Assignee: JOHN COCKERILL S.A.
    Inventor: Michel Dubois
  • Publication number: 20230257774
    Abstract: Provided herein are methods and compositions for a suicide gene approach comprising an expression vector comprising a cell cycle-dependent promoter driving the expression of a suicide gene. Also provided herein are methods to render proliferative cells sensitive to a prodrug after transplantation but avoids expression of the suicide gene in post-mitotic cells, such as neurons.
    Type: Application
    Filed: November 30, 2022
    Publication date: August 17, 2023
    Applicant: Research Development Foundation
    Inventors: Karl-Heinz KRAUSE, Michel DUBOIS-DAUPHIN, Vannary TIENG CAULET
  • Patent number: 11685984
    Abstract: A method for controlling and optimizing a transverse uniformity of a coating thickness on at least one side of a running metal strip in an industrial galvanization installation, the coating being deposited by hot dip coating in a pot containing a liquid metal bath, includes at least the steps of: heating the strip substrate to a temperature higher than a pot temperature; passing the strip through the bath by wrapping the strip around at least a first deflector roll or sink roll followed by at least one second deflector roll, the second deflector roll improving a flatness of the strip; wiping excess coating thickness carried away by the strip on one or both sides of the strip by wiping nozzles blowing a gas on the strip at an exit of the liquid metal bath; and measuring an actual distance profile between the nozzles and the strip.
    Type: Grant
    Filed: October 14, 2019
    Date of Patent: June 27, 2023
    Assignee: COCKERILL MAINTENANCE & INGENIERIE S.A.
    Inventors: Michel Dubois, Giuseppe Callegari
  • Patent number: 11639537
    Abstract: A gas blower device for blowing gas onto a surface of a traveling strip includes a plenum in the form of a hollow box for containing gas and comprising two side surfaces, a back surface and a front surface opposite to the back surface. The front surface having a profile of convex type symmetry with respect to a mid-plane perpendicular to the plane of the strip, so that a middle ridge of the front surface is located at the smallest distance from the plane of the strip. The front surface further presenting multiple tubular nozzles protruding at the front surface and having a gas outlet orifice facing in use the traveling strip. All the outlet orifices are essentially in a plane parallel to the strip plane. The gas blower device further includes a gas intake tube for feeding the plenum with gas.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: May 2, 2023
    Assignee: JOHN COCKERILL S.A.
    Inventors: Michel Dubois, Michel Boyer
  • Patent number: 11542524
    Abstract: Provided herein are methods and compositions for a suicide gene approach comprising an expression vector comprising a cell cycle-dependent promoter driving the expression of a suicide gene. Also provided herein are methods to render proliferative cells sensitive to a prodrug after transplantation but avoids expression of the suicide gene in post-mitotic cells, such as neurons.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: January 3, 2023
    Assignee: Research Development Foundation
    Inventors: Karl-Heinz Krause, Michel Dubois-Dauphin, Vannary Tieng Caulet
  • Publication number: 20220396861
    Abstract: The present invention relates to a gas wiping device for controlling the thickness of a coating layer deposited on a running metal strip plated with molten metal (1) in an industrial hot-dip installation, comprising a main nozzle unit (5) and a secondary nozzle unit (5A), to blow a wiping jet on the surface of the running strip, said main nozzle unit (5) and secondary nozzle unit (5A) being respectively provided with a main and secondary chamber (6, 6A) fed by pressurized non-oxidizing gas and with at least a main and N secondary elongated nozzle slot (7, 7A) formed in the tip of the respective main and secondary nozzle units (5, 5A), said tips comprising each an external top side (13, 13A), facing in use the downstream side of the running strip (1), and making an angle with the running strip surface, wherein the secondary nozzle unit (5A) is adjacent the main nozzle unit (5) over the external top side (13) of the main nozzle unit tip, so that the upper external surface (13A) of the secondary nozzle unit (5A)
    Type: Application
    Filed: November 25, 2020
    Publication date: December 15, 2022
    Inventor: Michel DUBOIS
  • Publication number: 20220317346
    Abstract: A multilayer architecture includes an amorphous optical layer, a crystalline optical layer overlying the amorphous optical layer, and a barrier layer located between the amorphous optical layer and the crystalline optical layer. The barrier layer may be configured to mediate the structure of the later-formed amorphous optical layer. For instance, a low absorption barrier layer may be formed over the crystalline optical layer within the multilayer architecture and accordingly inhibit crystallization within a subsequently formed optical layer, thus providing phase separation between the neighboring optical layers and a desired refractive index gradient within the multilayer architecture without adversely affecting the optical path length therethrough. Such a multilayer structure may be configured as a light retention layer, antireflective coating, bandpass filter, etc.
    Type: Application
    Filed: March 30, 2021
    Publication date: October 6, 2022
    Inventors: Elliott Franke, Nihar Ranjan Mohanty, Vivek Gupta, Geraud Jean-Michel Dubois
  • Publication number: 20220267801
    Abstract: Provided herein are methods and compositions for a suicide gene approach comprising an expression vector comprising a cell cycle-dependent promoter driving the expression of a suicide gene. Also provided herein are methods to render proliferative cells sensitive to a prodrug after transplantation but avoids expression of the suicide gene in post-mitotic cells, such as neurons.
    Type: Application
    Filed: May 11, 2022
    Publication date: August 25, 2022
    Applicant: Research Development Foundation
    Inventors: Karl-Heinz KRAUSE, Michel DUBOIS-DAUPHIN, Vannary TIENG CAULET
  • Publication number: 20220251677
    Abstract: A gas blower device for blowing gas onto a surface of a traveling strip includes a plenum in the form of a hollow box for containing gas and comprising two side surfaces, a back surface and a front surface opposite to the back surface. The front surface having a profile of convex type symmetry with respect to a mid-plane perpendicular to the plane of the strip, so that a middle ridge of the front surface is located at the smallest distance from the plane of the strip. The front surface further presenting multiple tubular nozzles protruding at the front surface and having a gas outlet orifice facing in use the traveling strip. All the outlet orifices are essentially in a plane parallel to the strip plane. The gas blower device further includes a gas intake tube for feeding the plenum with gas.
    Type: Application
    Filed: December 20, 2019
    Publication date: August 11, 2022
    Inventors: Michel Dubois, Michel Boyer
  • Patent number: 11371143
    Abstract: Provided is a pore-filling method for protecting the pores of a porous material. The method, which is performed using a modified i-CVD technique, involves filling the pores of a porous material with a gas phase monomer within a pressure chamber and subsequently polymerizing the monomer, both within the pores and on the surface of the material as an overburden. The method is solvent-free and can fill and protect pores of any size of any material.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: June 28, 2022
    Assignees: International Business Machines Corporation, Tokyo Electron Limited
    Inventors: Krystelle Lionti, Geraud Jean-Michel Dubois, Willi Volksen, Jacques Faguet
  • Patent number: 11339450
    Abstract: A method for controlling surface reactions on a steel strip running through a furnace includes, successively, a first section, a second section, and a third section separated by a sealing element, an atmosphere in the second and third sections being oxidizing and reducing respectively, the method including: heating, in the first section, the steel strip to between 600 and 750° C., while causing the atmosphere therein to be slightly oxidizing and to include: an H2 content inferior to 2%; an O2 content inferior to 0.1%; an H2O or CO2, or H2O+CO2 content superior to 0.03%; a controlled dew point ranging from ?50 to ?15° C.; and a controlled concentration of CO+CO2 maintained below 2%. All percentages are expressed in terms of volume.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: May 24, 2022
    Assignee: COCKERILL MAINTENANCE & INGENIERIE S.A.
    Inventor: Michel Dubois
  • Publication number: 20210381092
    Abstract: A method for controlling and optimizing a transverse uniformity of a coating thickness on at least one side of a running metal strip in an industrial galvanization installation, the coating being deposited by hot dip coating in a pot containing a liquid metal bath, includes at least the steps of: heating the strip substrate to a temperature higher than a pot temperature; passing the strip through the bath by wrapping the strip around at least a first deflector roll or sink roll followed by at least one second deflector roll, the second deflector roll improving a flatness of the strip; wiping excess coating thickness carried away by the strip on one or both sides of the strip by wiping nozzles blowing a gas on the strip at an exit of the liquid metal bath; and measuring an actual distance profile between the nozzles and the strip.
    Type: Application
    Filed: October 14, 2019
    Publication date: December 9, 2021
    Inventors: Michel DUBOIS, Giuseppe CALLEGARI
  • Patent number: 11193196
    Abstract: A furnace for annealing a sheet includes: a first section; a second vertical section, the second vertical section including openings supplied with an oxidizing medium, an opening facing each side of the sheet, and means for separately controlling a flow of the oxidizing medium on each side of the sheet; and a third section. The second vertical section is located in a distinct casing and separated from the first and third sections with sealing devices. The second vertical section includes extraction openings for extracting the oxidizing medium not consumed by the sheet, an extraction opening facing each side of the sheet. The openings supplied with an oxidizing medium are located transversally at one end of the second vertical section. The extraction openings are located transversally at an other end of the second vertical section.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: December 7, 2021
    Assignee: COCKERILL MAINTENANCE & INGÉNIERIE S.A.
    Inventor: Michel Dubois
  • Publication number: 20200378001
    Abstract: Provided is a pore-filling method for protecting the pores of a porous material. The method, which is performed using a modified i-CVD technique, involves filling the pores of a porous material with a gas phase monomer within a pressure chamber and subsequently polymerizing the monomer, both within the pores and on the surface of the material as an overburden. The method is solvent-free and can fill and protect pores of any size of any material.
    Type: Application
    Filed: May 31, 2019
    Publication date: December 3, 2020
    Inventors: Krystelle Lionti, Geraud Jean-Michel Dubois, Willi Volksen, Jacques Faguet
  • Patent number: 10801086
    Abstract: A continuous annealing furnace for annealing steel strips has a reaction chamber wherein the steel strips are transported vertically, the reaction chamber having openings supplied with a reactant, also called reactant openings, located at the top or at the bottom of the reaction chamber, wherein the reaction chamber further has other openings supplied with an inert gas, also called inert gas openings, the inert gas openings being located on the lateral sides of the reaction chamber.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: October 13, 2020
    Assignee: COCKERILL MAINTENANCE & INGENIERIE S.A.
    Inventor: Michel Dubois
  • Patent number: 10316399
    Abstract: The invention relates to equipment for cooling a metal strip (2) having a liquid coating to be solidified, wherein said strip is continuously moving. Said equipment is characterized in that each half-cooler (11, 12) is divided, over the length thereof, into at least two sections, a first section (13) and a second section (14), in the direction of the movement of the strip (2). The first section (13) is separated from the second section (14) in each half-cooler (11, 12) by a respective internal adjustment device (7, 8), making it possible to change the gas flow/pressure parameter so that the value of said gas flow/pressure parameter is different in the first section (13) from the value of said parameter in the second section (14).
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: June 11, 2019
    Assignee: Cockerill Maintenance & Ingéniérie S.A.
    Inventors: Stéphane Langevin, Michel Dubois
  • Publication number: 20190160113
    Abstract: Provided herein are methods and compositions for a suicide gene approach comprising an expression vector comprising a cell cycle-dependent promoter driving the expression of a suicide gene. Also provided herein are methods to render proliferative cells sensitive to a prodrug after transplantation but avoids expression of the suicide gene in post-mitotic cells, such as neurons.
    Type: Application
    Filed: November 29, 2018
    Publication date: May 30, 2019
    Inventors: Karl-Heinz KRAUSE, Michel DUBOIS-DAUPHIN, Vannary TIENG CAULET
  • Publication number: 20180363094
    Abstract: A continuous annealing furnace for annealing steel strips has a reaction chamber wherein the steel strips are transported vertically, the reaction chamber having openings supplied with a reactant, also called reactant openings, located at the top or at the bottom of the reaction chamber, wherein the reaction chamber further has other openings supplied with an inert gas, also called inert gas openings, the inert gas openings being located on the lateral sides of the reaction chamber.
    Type: Application
    Filed: March 23, 2016
    Publication date: December 20, 2018
    Inventor: Michel Dubois
  • Publication number: 20180306684
    Abstract: A stoning or honing device for automatically applying an essentially constant and uniform pressure of an abrasive hard component onto a suspended portion of a continuously moving metal strip surface, for the purpose of defect visual inspection, includes: a main frame supporting at least one carriage bearing a hard component, the carriage being connected to a drive system for moving the hard component towards the metal strip and to apply a controlled contact pressure thereof on the metal strip surface; and a means for moving transversally and back and forth at a defined speed the hard component bearing carriage with respect to a continuous motion direction of the strip. The device includes, on each strip side, a plurality of hard component bearing carriages having each a defined width stroke and arranged according to at least three different locations respectively associated with three separate rails including drive and control systems.
    Type: Application
    Filed: October 5, 2016
    Publication date: October 25, 2018
    Inventor: Michel Dubois