Patents by Inventor Michel Eichelbaum

Michel Eichelbaum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050227249
    Abstract: Described are general means and methods of diagnosing and treating the phenotypic spectrum as well as the overlapping clinical characteristics with several forms of inherited abnormal expression and/or function of the Multi Drug Resistance-1 (MDR-1) gene. In particular, polynucleotides of molecular variant MDR-1 genes which, for example, are associated with unsufficient and/or altered uptake of drugs by a target cell, and vectors comprising such polynucleotides are provided. Furthermore, host cells comprising such polynucleotides or vectors and their use for the production of variant MDR-1 proteins are described. In addition, variant MDR-1 proteins and antibodies specifically recognizing such proteins as well as concerns transgenic non-human animals comprising the above-described polynucleotide or vectors are provided.
    Type: Application
    Filed: October 14, 2004
    Publication date: October 13, 2005
    Inventors: Ulrich Brinkmann, Sven Hoffmeyer, Michel Eichelbaum, Ivar Roots
  • Patent number: 5057304
    Abstract: Antitumor compositions and methods in which a cancerostatic agent and an effective amount of (+)-verapamil, (+)-gallopamil, (+)-devapamil and/or (+)-emopamil which reinforce the antitumor action of the cancerostatic agent are administered to a patient either together or in sequence.
    Type: Grant
    Filed: January 3, 1989
    Date of Patent: October 15, 1991
    Assignee: BASF Aktiengesellschaft
    Inventors: Rolf Kretzschmar, Erich Schlick, Michel Eichelbaum