Abstract: The present invention relates to a process and an installation for purification of the helium contained in a mixture of gas, employing a pre-treatment unit to retain the impurities such as water, carbon dioxide gas and heavy organic compounds, and at least one reactor of the chromatographic type located downstream of said pre-treatment unit, said process comprising the following steps of:(a) adjusting the pressure of the mixture of gas until the working pressure of the phase of adsorption is obtained, this pressure being between 10 and 30 bars, and preferably 12 to 15 bars;(b) taking the temperature of the mixture of gas at the outlet of said pre-treatment unit until it is located in the range -15.degree. C./-35.degree. C., and preferably -25.degree. C.;(c) and sending the mixture of gas into the reactor and passing it through an absorbent, which is constituted by a microporous charcoal whose pores are of dimensions less than or equal to 20 .ANG..