Abstract: A coiling limitation device for a timepiece barrel includes at least one non-return notch arranged to cooperate with a sliding flange of the spring of the barrel, which is integrated in a watch including a resonator cooperating with an escapement mechanism. This device includes an acoustic device for the acoustic monitoring of the coiling of the barrel of a watch positioned on a receptacle included by the device, which acoustic devices are arranged to identify a click noise during each start of cooperation between the sliding flange and a notch. The device includes piloting devices arranged to stop the coiling of the barrel at the instant of the perception of the click noise or the repetition of the click noise.

Abstract: A purified human papillomavirus gene selected from the group consisting of E1, E6-E7, Li, and L2, wherein said human papillomavirus is selected from the group consisting of HPV-2d, HPV-10b, HPV-14a, HPV-14b, HPV-15, HPV-17a, HPV-17b, HPV-19, HPV-20, HPV-21, HPV-22, HPV-23, HPV-24, HPV-28, HPV-29, HPV-31, HPV32, HPV-1P2 and HPV-IP4. Polypeptides encoded by these genes. The polypeptides can be used in immunogenic compositions.

Abstract: A purified human papillomavirus gene selected from the group consisting of E1, E6-E7, L1, and L2, wherein said human papillomavirus is selected from the group consisting of HPV-2d, HPV-10b, HPV-14a, HPV-14b, HPV-15, HPV-17a, HPV-17b, HPV-19, HPV-20, HPV-21, HPV-22, HPV-23, HPV-24, HPV-28, HPV-29, HPV-31, HPV-32, HPV-IP2 and HPV-IP4. Polypeptides encoded by these genes. The polypeptides can be used in immunogenic compositions.

Abstract: The invention concerns human papillomavirus (HPV) DNA and more particularly the probes derived from these papillomaviruses, as well as the methods of detecting HPV using these probes. These human papillomaviruses are designated as HPV-2d, HPV-10b, HPV-14a, HPV-14b, HPV-15, HPV-17a, HPV-17b, HPV-19, HPV-20, HPV-21, HPV-22, HPV-23, HPV-24, HPV-28, HPV-29, HPV-31, HPV-32, HPV-IP2 and HPV-IP4.

Abstract: A purified human papillomavirus gene selected from the group consisting of E1, E6-E7, L1, and L2, wherein said human papillomavirus is selected from the group consisting of HPV-2d, HPV-10b, HPV-14a, HPV-14b, HPV-15, HPV-17a, HPV-17b, HPV-19, HPV-20, HPV-21, HPV-22, HPV-23, HPV-24, HPV-28, HPV-29, HPV-31, HPV-32, HPV-IP2 and HPV-IP4. Polypeptides encoded by these genes. The polypeptides can be used in immunogenic compositions.

Abstract: The invention relates to papillomavirus probes derived from new DNA-HPVs deposited with the CNCM on the May 6, 1988 under the following filing numbers:PGEM 4 HPV49: I-754PSP 65 HPV50: I-755PSP 64 HPV54: I-756PGEM 4 HPV55A: I-757PGEM 4 HPV55B: I-758These probes can be used for in vitro detection of:in the case of HPV49: warts of the skin (in particular, common and plantar warts) and the differential diagnosis of epidermodysplasia verruciformis,in the case of HPV50: epidermodysplasia verruciformis, intra-epithelial neoplasias and cutaneous cancers,in the case of HPV55: genital neoplasias and cancers of the uterine cervix,in the case of HPV55: genital neoplasias and cancers of the uterine cervix, condylomas and papillomas.

Abstract: The invention concerns human papillomavirus (HPV) DNA and more particularly the probes derived from these papillomaviruses, as well as the methods of detecting HPV using these probes. These human papillomaviruses are designated as HPV-2d, HPV-10b, HPV-14a, HPV-14b, HPV-15, HPV-17a, HPV-17b, HPV-19, HPV-20, HPV-21, HPV-22, HPV-23, HPV-24, HPV-28, HPV-29, HPV-31, HPV-32, HPV-IP2 and HPV-IP4.

Abstract: The invention relates to papillomavirus probes derived from new DNA-HPVs deposited with the CNCM on the 6 May 1988 under the following filing numbers:PGEM 4 HPV49: I-754PSP 65 HPV50: I-755PSP 64 HPV54: I-756PGEM 4 HPV55A: I-757PGEM 4 HPV55B: I-758These probes can be used for in vitro detection of:in the case of HPV49: warts of the skin (in particular, common and plantar warts) and the differential diagnosis of epidermodysplasia verruciformis,in the case of HPV50: epidermodysplasia verruciformis, intra-epithelial neoplasias and cutaneous cancers,in the case of HPV55: genital neoplasias and cancers of the uterine cervix,in the case of HPV55: genital neoplasias and cancers of the uterine cervix, condylomas and papillomas.

Abstract: The invention relates to human papillomaviruses HPV, particularly to HPV-DNAs isolated from papillomaviruses HPV-2d, HPV-10b, HPV-14a, HPV-14b, HPV-15, HPV-17a, HPV-17b, HPV-19, HPV-20, HPV-21, HPV-22, HPV-23, HPV-24, HPV-28, HPV-29, HPV-31, HPV-32, HPV-IP2 and HPV-IP4. The invention also relates to DNA capable of hybridizing with the HPV-DNAs or fragments thereof, to kits containing distinct groups of probes containing one or more of these HPV-DNAs or fragments thereof, and to procedures for detecting and identifying HPV in tissue.

Abstract: The invention relates to papillomavirus probes derived from new DNA-HPVs deposited with the C.N.C.M. on May 6, 1988, under the following filing numbers:______________________________________ PGEM 4 HPV49: I-754 PSP 65 HPV50: I-755 PSP 64 HPV54: I-756 PGEM 4 HPV55A: I-757 PGEM 4 HPV55B: I-758 ______________________________________These probes can be used for in vitro detection of:in the case of HPV49: warts of the skin (in particular, common and plantar warts) and the differential diagnosis of epidermodysplasia verruciformis,in the case of HPV50: epidermodysplasia verruciformis, intraepithelial neoplasias and cutaneous cancer,in the case of HPV55: genital neoplasias and cancers of the uterine cervix,in the case of HPV55: genital nepolasias and cancers of the uterine cervix, condylomas and papillomas.

Abstract: The invention relates to papillomavirus probes derived from new DNA-HPVs deposited with the C.N.C.M. on May 6, 1988, under the following filing numbers:______________________________________ PGEM 4 HPV49: I-754 PSP 65 HPV50: I-755 PSP 64 HPV54: I-756 PGEM 4 HPV55A: I-757 PGEM 4 HPV55B: I-758 ______________________________________These probes can be used for in vitro detection of:in the case of HPV49: warts of the skin (in particular, common and plantar warts) and the differential diagnosis of epidermodysplasia verruciformis,in the case of HPV50: epidermodysplasia verruciformis, intraepithelial neoplasias and cutaneous cancer,in the case of HPV55.sub.-- : genital neoplasias and cancers of the uterine cervix,in the case of HPV55.sub.-- : genital neoplasias and cancers of the uterine cervix, condylomas and papillomas.

Abstract: Restriction maps of DNA derived from Human Papillomavirus Types 49, 50, 54, and 55 are disclosed as well as methods for providing recombinant forms of same.

Abstract: A process yielding a glass blank in the form of a rod intended for drawing an optical fiber of the kind of self-focussing fiber i.e. having a radial refractive index gradient, having features (substantially transparency or transmission efficiency) lower than those of the fibers intended for long distance communication but sufficient for middle distance transmission, and which exhibits a lower cost than known processes. In a first stage a phase separation yields a "hard" phase (rich in silicon) and a "soft" phase (poor in silicon and rich in impurities) due to the drawing of a rod from a bath of molten glass through a cooling system having a strong temperature gradient and creating a radial refractive index gradient. In a second stage the soft phase is leached, eliminating the impurities contained in the soft phase but keeping safe the radial gradient. In a third stage a consolidation treatment is a pure annealing treatment rendering the hard phase more homogeneous.