Abstract: A device for cranial implantation includes a ferrule and a plate for placement in the ferrule. Furthermore, a neurological implant system includes a probe and a device for cranial implantation.

Abstract: The present application relates to a device for treating skin (1) comprising a housing (2), a shaft (14) located in the housing (2) having a longitudinal axis (‘A’) and an end for receiving a skin treating part (3). The device (1) further comprises a drive means configured to cause the shaft to rotate about its longitudinal axis, and to oscillate in a direction along the longitudinal axis, wherein the drive means comprise a rotational drive unit for rotating the shaft (14) and an oscillation generator (26) for oscillating the shaft. The oscillation generator (26) is located about the shaft (14) such that the shaft is rotatable relative to the oscillation generator. Furthermore, the oscillation generator (26) comprises a solenoid (39) and a flux assembly (25), and the flux assembly (25) is moveable along the shaft (14) relative to the solenoid (39).

Abstract: A medicament delivery device, which comprises a driving mechanism and a housing (1) having a reservoir (2), which is at least partly filled with a substance and which is sealed at least on one side with a flexible wall (21). The driving mechanism is adapted to press a piston (23) against the flexible wall (21) thereby releasing the substance from the reservoir (2) through an opening (25) in the reservoir (2). This provides for a safe and reliable medicament delivery device.

Abstract: A medicament delivery device, which comprises a driving mechanism and a housing (1) having a reservoir (2), which is at least partly filled with a substance and which is sealed at least on one side with a flexible wall (21). The driving mechanism is adapted to press a piston (23) against the flexible wall (21) thereby releasing the substance from the reservoir (2) through an opening (25) in the reservoir (2). This provides for a safe and reliable medicament delivery device.

Abstract: The invention relates to an electronic pill (102) for delivery of a medication (104) inside a mammal. The electronic pill (102) comprises a reservoir (106) for releasing the medication (104) in response to a predefined level of pressure. Furthermore a primary elastic element (108) is comprised for applying said predefined level of pressure to the reservoir (106) via a piston (110) upon release from the piston (110) of its constrained position. The piston (110) in its turn, when in constrained position, induces a predefined level of stress in the primary elastic element (108) by accordingly deforming it. The electronic pill (102) comprises a mechanism (114) for changing, upon actuation, from a constraining configuration in which the piston (110) is maintained at its constrained position to a releasing configuration in which the piston (110) is released.

Abstract: A method of manufacturing a personalized radio frequency (RF) coil array for magnetic resonance (MR) imaging guided interventions includes: acquiring diagnostic image data reflecting the anatomy of a portion of a patient's body; planning an intervention on the basis of the diagnostic image data, wherein a field of the intervention within the patient's body portion is determined; and arranging one or more RF coils on a substrate which is adapted to the patient's anatomy, in such a manner that the signal-to-noise ratio of MR signal acquisition via the one or more RF coils from the field of the intervention is optimized.

Abstract: The present invention regards a guiding tool for neurosurgery. The guiding tool comprises subunits and a holder. The subunits are arranged in the holder so that holes for guiding a probe are created in the interface between said subunits, which allows easy release of the probe. The invention further regards a system for guiding neurosurgery probes.

Abstract: The invention relates a system (302) for medical stimulation. The system (302) comprises an implantable probe (304) bifurcated into a primary branch (306) and a secondary branch (308) at a bifurcation (310), wherein the probe is provided at its distal end (112, 312) with an electrode (114) for delivering electrical stimulation to tissue. Herein, the primary branch (306) is configured for at least temporarily mechanically co-operating with a guide wire (316) configured for guiding the probe (304) into said tissue whereas the secondary branch (308) is configured for electrically connecting said electrode to a device for generating the electrical stimulation.

Abstract: The present application relates to a device for treating skin (1) comprising a housing (2), a shaft (14) located in the housing (2) having a longitudinal axis (‘A’) and an end for receiving a skin treating part (3). The device (1) further comprises a drive means configured to cause the shaft to rotate about its longitudinal axis, and to oscillate in a direction along the longitudinal axis, wherein the drive means comprise a rotational drive unit for rotating the shaft (14) and an oscillation generator (26) for oscillating the shaft. The oscillation generator (26) is located about the shaft (14) such that the shaft is rotatable relative to the oscillation generator. Furthermore, the oscillation generator (26) comprises a solenoid (39) and a flux assembly (25), and the flux assembly (25) is moveable along the shaft (14) relative to the solenoid (39).

Abstract: The invention relates to an electronic pill (102) for delivery of a medication (104) inside a mammal. The electronic pill (102) comprises a reservoir (106) for releasing the medication (104) in response to a predefined level of pressure. Furthermore a primary elastic element (108) is comprised for applying said predefined level of pressure to the reservoir (106) via a piston (110) upon release from the piston (110) of its constrained position. The piston (110) in its turn, when in constrained position, induces a predefined level of stress in the primary elastic element (108) by accordingly deforming it. The electronic pill (102) comprises a mechanism (114) for changing, upon actuation, from a constraining configuration in which the piston (110) is maintained at its constrained position to a releasing configuration in which the piston (110) is released.

Abstract: A kit includes a swallowable capsule (1, 45) with a potentiometric sensor (3), such as a pH sensor, with an unfilled electrolyte cell (31). The kit further includes a separate container (46) containing a liquid electrolyte. The kit can, e.g., be packed in a blister package. After unpacking the capsule the electrolyte cell (31) is filled with the electrolyte.

Abstract: The invention relates to a method of manufacturing a personalized RF coil array for MR imaging guided interventions. The method comprises the steps of: —acquiring diagnostic image data reflecting the anatomy of a portion of a patient's body (10); —planning an intervention on the basis of the diagnostic image data, wherein a field of the intervention within the patient's body (10) portion is determined; —arranging one or more RF antennae (11, 12, 13) on a substrate (19), which is adapted to the patient's anatomy, in such a manner that the signal-to-noise ratio of MR signal acquisition via the one or more RF antennae (11, 12, 13) from the field of the intervention is optimized. Moreover, the invention relates to a computer program and to a computer workstation.

Abstract: A steering system (30) comprises two radially oppositely arranged drive wheels (1; 3) for steering a tubular object (5) positioned between the drive wheels (1; 3). The drive wheels (1; 3) each have a wheel rotation axis (40; 42) and each include a plurality of rollers (7) distributed around the wheel rotation axis (40; 42). The rollers (7) are rotatably arranged, each roller having a roller rotation axis (44) and an outer drive face (58) concavely vaulted in a direction corresponding to its roller rotation axis (44). The roller rotation axis (44) is obliquely oriented in relation to the wheel rotation axis (40; 42) and the rollers (7) of each drive wheel (1; 3) form together a steering periphery for the tubular object (5). The steering system enables continues rotation of a tubular object without danger that the object will lose the contact with the rollers. The steering system (30) may be incorporated in a catheter system which comprises a catheter (5).

Abstract: An ingestible electronic capsule (100) for introduction into the bodily lumen comprises a circuit board with at least one electronic component (4, 5, 7, 8, 9, 11, 12, 13, 14). The circuit board is formed from a flex foil (10), thereby reducing the number of components and improving the robustness and reliability of the ingestible electronic capsule (100).

Abstract: A system (102) comprising a box (104) for implanting in a mammal body part (106), which box is provided with a first electrical contact (110, 121, 114, 116, 118, 120), and a module (108) for accommodating in the box, which module is provided with a second electrical contact (122, 124, 126) for cooperation with said first electrical contact. The first electrical contact and the second electrical contact are mutually movable, at least in a stationary accommodation of the module in the box, between a contact position in which said first and second electrical contacts are electrically connected, and a non-contact position in which said first and second electrical contacts are separated from each other.

Abstract: A medical probe is provided that has a single longitudinally uniform interconnect that provides a connection between a distal end and a proximal end of the probe. The interconnect is obtained by forming a thin uniform film as a spiral on a wafer and subsequently applying this spiral as a helix on a base element of a medical probe. The thin film spiral is manufactured with multiple connecting wires to enable connection between an electronics module and a multiplicity of electrodes (an electrode array) at the distal end of the medical probe.

Abstract: The invention relates a system (302) for medical stimulation. The system (302) comprises an implantable probe (304) bifurcated into a primary branch (306) and a secondary branch (308) at a bifurcation (310), wherein the probe is provided at its distal end (112, 312) with an electrode (114) for delivering electrical stimulation to tissue. Herein, the primary branch (306) is configured for at least temporarily mechanically co-operating with a guide wire (316) configured for guiding the probe (304) into said tissue whereas the secondary branch (308) is configured for electrically connecting said electrode to a device for generating the electrical stimulation.

Abstract: A steering system (30) comprises two radially oppositely arranged drive wheels (1; 3) for steering a tubular object (5) positioned between the drive wheels (1; 3). The drive wheels (1; 3) each have a wheel rotation axis (40; 42) and each include a plurality of rollers (7) distributed around the wheel rotation axis (40; 42). The rollers (7) are rotatably arranged, each roller having a roller rotation axis (44) and an outer drive face (58) concavely vaulted in a direction corresponding to its roller rotation axis (44). The roller rotation axis (44) is obliquely oriented in relation to the wheel rotation axis (40; 42) and the rollers (7) of each drive wheel (1; 3) form together a steering periphery for the tubular object (5). The steering system enables continues rotation of a tubular object without danger that the object will lose the contact with the rollers. The steering system (30) may be incorporated in a catheter system which comprises a catheter (5).

Abstract: A medical probe is provided that has a single longitudinally uniform interconnect that provides a connection between a distal end and a proximal end of the probe. The interconnect is obtained by forming a thin uniform film as a spiral on a wafer and subsequently applying this spiral as a helix on a base element of a medical probe. The thin film spiral is manufactured with multiple connecting wires to enable connection between an electronics module and a multiplicity of electrodes (an electrode array) at the distal end of the medical probe.

Abstract: A lithographic projection apparatus having a masking device for obscuring part of at least one of a patterning device used for patterning a projection beam before imaging the patterned beam onto a substrate. The masking device includes a first masking structure to obscure said part of said patterning device in a first direction and a second masking structure to obscure said part in a second different direction, wherein said first and second masking structure are disposed in the vicinity of said focal plane in a mechanically uncoupled arrangement with respect to each other.