Patents by Inventor Michel Heaulme

Michel Heaulme has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5292745
    Abstract: The invention concerns the use of a compound of formula (I) ##STR1## wherein R and R.sub.1, each independently, represent a hydrogen atom or a methyl group, and its pharmaceutically acceptable acid addition salts, as free radical scavengers. The pharmaceutical compositions containing these compounds may be employed in the treatment and/or prevention of pathological processes involving cell damage due to the formation of free radicals.The invention also concerns the compounds of formula (I) wherein at least one of R and R.sub.1 is methyl, which are new compounds, as well as the process for the preparation thereof and the pharmaceutical compositions containing them.
    Type: Grant
    Filed: February 4, 1992
    Date of Patent: March 8, 1994
    Assignee: Elf Sanofi
    Inventors: Michel Heaulme, Umberto Guzzi
  • Patent number: 4873243
    Abstract: The invention relates to derivatives of 2,3-dihydro 3-imino-pyridazine responding to general formula: ##STR1## in which: A represents an atom of oxygen or of sulfur;R.sub.1 represents a lower alkyl group, or an aromatic group selected from:the phenyl group;the phenyl groups mono- or poly-substituted by a halogen group, a lower alkyl group, a lower alkoxy group, a nitro group, a hydroxy or methylenedioxy group;the naphthyl group;the furyl group;the thienyl group or the pyridyl group;R.sub.2 and R.sub.3 each designate independently hydrogen or a lower alkyl group; a phenyl group, or R.sub.2 and R.sub.3, taken together, constitute, with the 2 atoms of the pyridazinic cycle to which they are bonded, a benzene ring, and their pharmaceutically acceptable salts. Application: antidepressants or psychotonics.
    Type: Grant
    Filed: October 28, 1986
    Date of Patent: October 10, 1989
    Assignee: SANOFI
    Inventors: Camille G. Wermuth, Gilbert Schlewer, Michel Heaulme