Patents by Inventor Michel Hocquaux

Michel Hocquaux has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230255864
    Abstract: The present invention relates to an association comprising or consisting of a mixture of cannabidiol or cannahigerol and palinitoyl tripeptide-8, and to the use thereof for treating or soothing sensitive and/or reactive skins or as an after-sun ointment for soothing solar erythema.
    Type: Application
    Filed: July 13, 2021
    Publication date: August 17, 2023
    Inventors: Michel HOCQUAUX, Jean-Christophe AUBAGNAC
  • Publication number: 20220323534
    Abstract: New compositions containing an extract of Tulipa Gesneriana. The compositions include a tulip extract from the Tulipa Gesneriana family, acetyl-tetrapeptide-2, and acetyl-hexapeptide-51 amide. Also, the use thereof in cosmetics, and the use thereof in pharmaceuticals, particularly in dermatology for treating or preventing skin aging, and the use thereof in pharmaceuticals, particularly in dermatology, for treating or preventing pathologies linked to oxidative stress.
    Type: Application
    Filed: September 4, 2020
    Publication date: October 13, 2022
    Applicant: FRANCE COSMEPHYL-LAB
    Inventors: Michel HOCQUAUX, Jean-Christophe AUBAGNAC
  • Publication number: 20210188911
    Abstract: The object of the present invention relates to a novel family of peptide conjugates of formula (I): A-X1—X2-Pro-Ala-X—B ??(I) wherein: A represents a hydrogen atom, a C6 to C20 acyl group or a cholesterol residue; X1 represents a covalent bond, an alanine or a proline; X2 represents an arginine, a lysine, or an alanine; X represents a lysine, an alanine, or a phenylalanine; and B represents a hydroxyl or an amine; or one of its preferentially pharmaceutically, dermatologically or cosmetically acceptable salts, as well as their synthesis processes and their uses for reducing hair loss and stimulating hair growth.
    Type: Application
    Filed: January 27, 2021
    Publication date: June 24, 2021
    Applicants: Institut Europeen de Biologie Cellulaire, Centre de Recherches Biologiques et d'Experimentations Cutanees, Centre National de la Recherche Scienfitique (CNRS)
    Inventors: Michel Hocquaux, Stéphanie Almeida Épouse Scalvino, Elian Lati, Joanna Bakala
  • Patent number: 10947273
    Abstract: The object of the present invention relates to a novel family of peptide conjugates of formula (I): A-X1-X2-Pro-Ala-X—B??(I) wherein: A represents a hydrogen atom, a C6 to C20 acyl group or a cholesterol residue; X1 represents a covalent bond, an alanine or a proline; X2 represents an arginine, a lysine, or an alanine; X represents a lysine, an alanine, or a phenylalanine; and B represents a hydroxyl or an amine; or one of its preferentially pharmaceutically, dermatologically or cosmetically acceptable salts, as well as their synthesis processes and their uses for reducing hair loss and stimulating hair growth.
    Type: Grant
    Filed: October 10, 2016
    Date of Patent: March 16, 2021
    Assignees: Institut European de Biologic Cellulaire, Centre de Recherches Biologiques et d'Experimentations Cutanees, Centre National de la Recherche Scientifique (CNRS)
    Inventors: Michel Hocquaux, Stéphanie Almeida Épouse Scalvino, Elian Lati, Joanna Bakala
  • Publication number: 20180291061
    Abstract: The object of the present invention relates to a novel family of peptide conjugates of formula (I): A-X1-X2-Pro-Ala-X-B??(I) wherein: A represents a hydrogen atom, a C6 to C20 acyl group or a cholesterol residue; X1 represents a covalent bond, an alanine or a proline; X2 represents an arginine, a lysine, or an alanine; X represents a lysine, an alanine, or a phenylalanine; and B represents a hydroxyl or an amine; or one of its preferentially pharmaceutically, dermatologically or cosmetically acceptable salts, as well as their synthesis processes and their uses for reducing hair loss and stimulating hair growth.
    Type: Application
    Filed: October 10, 2016
    Publication date: October 11, 2018
    Applicants: Institut Europeen de Biologie Cellulaire, Centre de Recherches Biologiques et d'Experimentations Cutanees, Centre National de la Recherche Scienfitique (CNRS)
    Inventors: Michel Hocquaux, Stéphanie Almeida Épouse Scalvino, Elian Lati, Joanna Bakala
  • Patent number: 9115176
    Abstract: A compound of the formula I: R-A-Gly-His-B (I) wherein: A and B are independently of each other a L-lysine residue, a D-lysine residue, or a L- or D-lysine residue in which the NH2 group of the side chain comprises a modification, where-in said modification is (i) a replacement with a hydrogen, (ii) an acetylation, (iii) a benzoylation, or (iv) a palmitoylation; GIy is a glycine residue; His is a L- or D-histidine residue; R is CH3—(CH2)n—CO—, wherein n=2, 3, 4, 5, 6, 7 or 8; R? is a group of formula (II): N(Z)(Z?) (II) wherein: Z and Z? is hydrogen, a methyl group, an ethyl group, a phenyl group, an hexyl group, a decyl group or an hexadecyl group; or a racemate, an enantiomer or a diastereomer thereof, or mixtures thereof, or a salt thereof.
    Type: Grant
    Filed: June 30, 2008
    Date of Patent: August 25, 2015
    Assignee: Lucas Meyer Cosmetics Canada Inc.
    Inventors: Michel Hocquaux, Estelle Loing, Philippe Bedos
  • Patent number: 8372455
    Abstract: Cosmetic compositions with anti-free radical activity have been developed. Such compositions preferably contain an association of at least the following three substances with anti-free radical activity: an extract of emblica, idebenone and N-acetylcysteine.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: February 12, 2013
    Assignee: LVMH Recherche
    Inventors: Patrice Andre, Isabelle Renimel, Céline Godenir, Michel Hocquaux
  • Patent number: 8367085
    Abstract: Cosmetic compositions with anti-free radical activity have been developed. Such compositions preferably contain an association of at least the following three substances with anti-free radical activity: idebenone; N-acetylcysteine, and alpha-tocotrienol or an ester thereof with a C2-C4 organic acid.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: February 5, 2013
    Assignee: LVMH Recherche
    Inventors: Patrice Andre, Isabelle Renimel, Céline Godenir, Michel Hocquaux
  • Publication number: 20110250304
    Abstract: Cosmetic compositions with anti-free radical activity have been developed. Such compositions preferably contain an association of at least the following three substances with anti-free radical activity: an extract of emblica, idebenone and N-acetylcysteine.
    Type: Application
    Filed: June 21, 2011
    Publication date: October 13, 2011
    Applicant: LYMH RECHERCHE
    Inventors: Patrice ANDRE, Isabells Renimel, Celine Godenir, Michel Hocquaux
  • Publication number: 20110251271
    Abstract: Cosmetic compositions with anti-free radical activity have been developed. Such compositions preferably contain an association of at least the following three substances with anti-free radical activity: idebenone; N-acetylcysteine, and alpha-tocotrienol or an ester thereof with a C2-C4 organic acid.
    Type: Application
    Filed: June 21, 2011
    Publication date: October 13, 2011
    Applicant: LVMH RECHERCHE
    Inventors: Patrice ANDRE, Isabelle Renimel, Celine Godenir, Michel Hocquaux
  • Patent number: 7988982
    Abstract: A cosmetic composition has an association of at least three of the following substances with anti-free radical activity, selected from: 1) ebselen; or idebenone; or an association of the two; and 2) at least one substance with anti-free radical activity, or at least two substances with anti-free radical activity for obtaining said association of at least three substances with anti-free radical activity, said substance(s) being selected from: a) a substance of chemical formula (I) below: in which: R=a linear or branched, saturated or unsaturated C1-C16 hydrocarbon chain; and R1, R2 and R3 are identical or different and are a hydrogen atom or a methyl or methoxy radical, and its esters; b) an extract of Edelweiss; c) an extract of Emblica; and d) N-acetylcysteine. The anti-free radical activity is greatly improved.
    Type: Grant
    Filed: June 11, 2007
    Date of Patent: August 2, 2011
    Assignee: LVMH Recherche
    Inventors: Patrice Andre, Isabelle Renimel, Céline Godenir, Michel Hocquaux
  • Publication number: 20100310484
    Abstract: A peptide of formula I (SEQ ID NO: 1): Lip-A-Gly-His-B-R (I) wherein: Lip is a lipoyl residue of R or S configuration; A is absent or is a lysine residue of configuration L or D; GIy is a glycine residue; His is a histidine residue of configuration L or D; B is a lysine residue of configuration L or D, or a lysine residue of configuration L or D in which the NH2 group of the side chain comprises a modification, wherein said modification is (i) a replacement with a hydrogen or (ii) a modification with a protecting group selected from the group consisting of acetyl, benzoyl, tosyl, sulfonyl benzene, benzyloxycarbonyle and palmitoyl; wherein R is O(Z) or N(Z?)(Z?), and wherein Z, Z? and Z? are independently of each other a hydrogen or a protecting group selected from the group consisting of methyl, ethyl, propyl, phenyl, hexyl, decyl and hexadecyl, or a racemate, an enantiomer or a diastereomer thereof, or a mixture thereof, or a salt thereof.
    Type: Application
    Filed: June 30, 2008
    Publication date: December 9, 2010
    Applicant: Innovactiv Inc.
    Inventors: Michel Hocquaux, Estelle Loing, Philippe Bedos
  • Publication number: 20100311667
    Abstract: A compound of the formula I: R-A-Gly-His-B (I) wherein: A and B are independently of each other a L-lysine residue, a D-lysine residue, or a L- or D-lysine residue in which the NH2 group of the side chain comprises a modification, where-in said modification is (i) a replacement with a hydrogen, (ii) an acetylation, (iii) a benzoylation, or (iv) a palmitoylation; GIy is a glycine residue; His is a L- or D-histidine residue; R is CH3—(CH2)n—CO—, wherein n=2, 3, 4, 5, 6, 7 or 8; R? is a group of formula (II): N(Z)(Z?) (II) wherein: Z and Z? is hydrogen, a methyl group, an ethyl group, a phenyl group, an hexyl group, a decyl group or an hexadecyl group; or a racemate, an enantiomer or a diastereomer thereof, or mixtures thereof, or a salt thereof.
    Type: Application
    Filed: June 30, 2008
    Publication date: December 9, 2010
    Applicant: Innovactiv Inc.
    Inventors: Michel Hocquaux, Estelle Loing, Philippe Bedos
  • Patent number: 7785577
    Abstract: The invention relates to a peptide of formula W-DPhe-Arg-Z (I) and to a conjugate thereof of a formula A-W-DPhe-Arg-Z (II), wherein A is a radical corresponding to a monocarboxylic acid of general formula HOOC—R (III), wherein R is an linear or branched possibly substituted by a hydroxy group aliphatic C1-C24 radical which can comprise one or several unsaturations, preferably from 1 to 6 unsaturations, a lipoic acid or the reduced form thereof, a dihydrolipoic acid, N-lipoyl-lysine or a phenylbutyric acid, W is His, Ala-His, Ala-Ala-His, Nle-Ala-His, DTrp-Ala-His, Nle-Trp-His, Lys, Ala-Lys, Nle-Ala-Lys, Orn, Ala-Orn, Nle-Ala-Orn, Ala, Nle-Ala-Ala, Arg, Ala-Arg.
    Type: Grant
    Filed: May 10, 2005
    Date of Patent: August 31, 2010
    Assignees: Institut Europeen de Biologie Cellulaiare, Centre National de la Recherche Scientifique (CNRS), Universite de Montpellier I, Universite de Montpellier II
    Inventors: Michel Hocquaux, Anne-Marie Pinel, Jean Martinez, Gilles Subra
  • Publication number: 20090142420
    Abstract: A cosmetic composition has an association of at least three of the following substances with anti-free radical activity, selected from: A cosmetic composition has an association of at least three of the following substances with anti-free radical activity, selected from: 1) ebselen; or idebenone; or an association of the two; and 2) at least one substance with anti-free radical activity, or at least two substances with anti-free radical activity for obtaining said association of at least three substances with anti-free radical activity, said substance(s) being selected from: a) a substance of chemical formula (I) below: in which: R=a linear or branched, saturated or unsaturated C1-C16 hydrocarbon chain; and R1, R2 and R3 are identical or different and are a hydrogen atom or a methyl or methoxy radical, and its esters; b) an extract of Edelweiss; c) an extract of Emblica; and d) N-acetylcysteine. The anti-free radical activity is greatly improved.
    Type: Application
    Filed: June 11, 2007
    Publication date: June 4, 2009
    Applicant: LVMH RECHERCHE
    Inventors: Patrice Andre, Isabelle Renimel, Celine Godenir, Michel Hocquaux
  • Patent number: 7507719
    Abstract: The invention relates to the use of peptidic conjugates containing Gly-His-Lys for producing dermatological or cosmetological compositions for stimulating hair growth or stopping hair fall.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: March 24, 2009
    Assignee: Institut European De Biologie Cellulaire
    Inventors: Anne-Marie Pinel, Michel Hocquaux
  • Publication number: 20080200396
    Abstract: The invention relates to a peptide of formula W-DPhe-Arg-Z (I) and to a conjugate thereof of a formula A-W-DPhe-Arg-Z (II), wherein A is a radical corresponding to a nionocarboxylic acid of general formula HOOC—R (III), wherein R is an linear or branched possibly substituted by a hydroxy group aliphatic C1-C24 radical which can comprise one or several unsaturations, preferably from 1 to 6 unsaturations, a lipoic acid or the reduced form thereof, a dihydrolipoic acid, N-lipoyl-lysine or a phenylbutyric acid, W is His, Ala-His, Ala-Ala-His, Nle-Ala-His, DTrp-Ala-His, Nle-Trp-His, Lys, Ala-Lys, Nle-Ala-Lys, Orn, Ala-Orn, Nle-Ala-Orn, Ala, Nle-Ala-Ala, Arg, Ala-Arg.
    Type: Application
    Filed: May 10, 2005
    Publication date: August 21, 2008
    Applicants: INSTITUT EUROPEN DE BIOLOGIE CELLULAIRE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS, UNIVERSITE DE MONTPELLIER I, UNIVERSITE MONTPELLIER II
    Inventors: Michel Hocquaux, Anne-Marie Pinel, Jean Martinez, Gilles Subra
  • Patent number: 7404948
    Abstract: The invention relates to novel peptidic conjugates containing a Gly-His-Lys sequence and used for dermatology or cosmetology for stimulating hair growth or stopping hair fall.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: July 29, 2008
    Assignee: Institut Europeen de Biologie Cellulaire
    Inventors: Anne-Marie Pinel, Michel Hocquaux
  • Publication number: 20070014747
    Abstract: The invention relates to novel peptidic conjugates containing a Gly-His-Lys sequence and used for dermatology or cosmetology for stimulating hair growth or stopping hair fall.
    Type: Application
    Filed: July 16, 2004
    Publication date: January 18, 2007
    Inventors: Anne-Marie Pinel, Michel Hocquaux
  • Publication number: 20070004633
    Abstract: The invention relates to the use of peptidic conjugates containing Gly-His-Lys for producing dermatological or cosmetological compositions for stimulating hair growth or stopping hair fall.
    Type: Application
    Filed: July 16, 2004
    Publication date: January 4, 2007
    Inventors: Anne-Marie Pinel, Michel Hocquaux