Patents by Inventor Michel J. N. Cormier

Michel J. N. Cormier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170135951
    Abstract: Compositions of and methods for formulating and delivering biologically active agent formulations having enhanced physical stability, and wherein deterioration from the presence of oxygen and/or water is minimized and/or controlled, to yield a stable formulation. The compositions of and methods for formulating and delivering biologically active agents of the present invention further facilitate their incorporation into a biocompatible coating which can be employed to coat a stratum-corneum piercing microprojection, or a plurality of stratum-corneum piercing microprojections of a delivery device, for delivery of the biocompatible coating through the skin of a subject, thus providing an effective means of delivering the biologically active agents.
    Type: Application
    Filed: January 30, 2017
    Publication date: May 18, 2017
    Inventors: Mahmoud Ameri, Michel J.N. Cormier, Scott Sellers, Yuh-Fun Maa
  • Patent number: 9573717
    Abstract: Compositions of and methods for formulating and delivering biologically active agent formulations having enhanced physical stability, and wherein deterioration from the presence of oxygen and/or water is minimized and/or controlled, to yield a stable formulation. The compositions of and methods for formulating and delivering biologically active agents of the present invention further facilitate their incorporation into a biocompatible coating which can be employed to coat a stratum-corneum piercing microprojection, or a plurality of stratum-corneum piercing microprojections of a delivery device, for delivery of the biocompatible coating through the skin of a subject, thus providing an effective means of delivering the biologically active agents.
    Type: Grant
    Filed: January 21, 2014
    Date of Patent: February 21, 2017
    Assignee: ALZA CORPORATION
    Inventors: Mahmoud Ameri, Michel J. N. Cormier, Scott Sellers, Yuh-Fun Maa
  • Publication number: 20160374955
    Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.
    Type: Application
    Filed: September 13, 2016
    Publication date: December 29, 2016
    Applicant: ALZA Corporation
    Inventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J.N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
  • Patent number: 9446004
    Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: September 20, 2016
    Assignee: ALZA CORPORATION
    Inventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J. N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
  • Patent number: 9295714
    Abstract: An apparatus and method for transdermally delivering a biologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of microprojections (or array thereof) that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers. In one embodiment, the PTH-based agent is contained in a biocompatible coating that is applied to the microprojection member.
    Type: Grant
    Filed: June 8, 2009
    Date of Patent: March 29, 2016
    Assignee: Alza Corporation
    Inventors: Mahmoud Ameri, Michel J. N. Cormier, Yuh-Fun Maa, Peter E. Daddona, Marika Kamberi
  • Publication number: 20150246007
    Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.
    Type: Application
    Filed: May 18, 2015
    Publication date: September 3, 2015
    Applicant: ALZA Corporation
    Inventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J.N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
  • Patent number: 9056061
    Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.
    Type: Grant
    Filed: September 22, 2006
    Date of Patent: June 16, 2015
    Assignee: ALZA Corporation
    Inventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J. N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
  • Patent number: 8920817
    Abstract: The invention provides for a formulation for coating one or more microprojections which reduces or minimizes the loss of counterions from the coating in order to achieve a pH-stabilized formulation.
    Type: Grant
    Filed: August 24, 2009
    Date of Patent: December 30, 2014
    Assignee: Alza Corporation
    Inventors: Mahmoud Ameri, Wei-Qi Lin, Michel J. N. Cormier, Yuh-Fun Maa
  • Publication number: 20140260096
    Abstract: Compositions of and methods for formulating and delivering biologically active agent formulations having enhanced physical stability, and wherein deterioration from the presence of oxygen and/or water is minimized and/or controlled, to yield a stable formulation. The compositions of and methods for formulating and delivering biologically active agents of the present invention further facilitate their incorporation into a biocompatible coating which can be employed to coat a stratum-corneum piercing microprojection, or a plurality of stratum-corneum piercing microprojections of a delivery device, for delivery of the biocompatible coating through the skin of a subject, thus providing an effective means of delivering the biologically active agents.
    Type: Application
    Filed: January 21, 2014
    Publication date: September 18, 2014
    Applicant: ALZA CORPORATION
    Inventors: Mahmoud Ameri, Michel J.N. Cormier, Scott Sellers, Yuh-Fun Maa
  • Patent number: 8663155
    Abstract: A device (12) and method are provided for percutaneous transdermal delivery of a potent pharmacologically active agent. The agent is dissolved in water to form an aqueous coating solution having an appropriate viscosity for coating extremely tiny skin piercing elements (10). The coating solution is applied to the skin piercing elements (10) using known coating techniques and then dried. The device (12) is applied to the skin of a living animal (e.g., a human), causing the microprotrusions (10) to pierce the stratum corneum and deliver a therapeutically effect dose of the agent to the animal.
    Type: Grant
    Filed: February 2, 2006
    Date of Patent: March 4, 2014
    Assignee: Alza Corporation
    Inventors: Michel J. N. Cormier, Wendy A. Young, Kofi Nyam, Peter E. Daddona, Wei-Qi Lin
  • Patent number: 8632801
    Abstract: Compositions of and methods for formulating and delivering biologically active agent formulations having enhanced physical stability, and wherein deterioration from the presence of oxygen and/or water is minimized and/or controlled, to yield a stable formulation. The compositions of and methods for formulating and delivering biologically active agents of the present invention further facilitate their incorporation into a biocompatible coating which can be employed to coat a stratum-corneum piercing microprojection, or a plurality of stratum-corneum piercing microprojections of a delivery device, for delivery of the biocompatible coating through the skin of a subject, thus providing an effective means of delivering the biologically active agents.
    Type: Grant
    Filed: December 28, 2006
    Date of Patent: January 21, 2014
    Assignee: Alza Corporation
    Inventors: Mahmoud Ameri, Michel J. N. Cormier, Scott Sellers, Yuh-Fun Maa
  • Patent number: 8633159
    Abstract: An apparatus and method for transdermally delivering a biologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of microprojections (or array thereof) that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers. In one embodiment, the PTH-based agent is contained in a biocompatible coating that is applied to the microprojection member.
    Type: Grant
    Filed: March 2, 2010
    Date of Patent: January 21, 2014
    Assignee: Alza Corporation
    Inventors: Mahmoud Ameri, Michel J. N. Cormier, Yuh-Fun Maa, Marika Kamberi, Peter E. Daddona
  • Patent number: 8440220
    Abstract: A transdermal analgesic system having reduced potential for abuse, wherein the system provides for the controlled release of the antagonist at a rate sufficient to provide an abuse limiting release rate ratio of the antagonist to the analgesic when the dosage form is subject to abuse is disclosed.
    Type: Grant
    Filed: April 22, 2003
    Date of Patent: May 14, 2013
    Assignee: Durect Corporation
    Inventors: Robert M. Gale, Thomas M. Stein, Jay Audett, Jane Stepic, Joseph B. Phipps, Michel J. N. Cormier
  • Patent number: 8361022
    Abstract: An apparatus and method for transdermally delivering a biologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of microprojections (or array thereof) that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers. In one embodiment, the PTH-based agent is contained in a biocompatible coating that is applied to the microprojection member.
    Type: Grant
    Filed: July 1, 2009
    Date of Patent: January 29, 2013
    Assignee: Alza Corporation
    Inventors: Mahmoud Ameri, Michel J. N. Cormier, Yuh-Fun Maa, Peter E. Daddona, Marika Kamberl
  • Patent number: 7963935
    Abstract: The device including a plurality of stratum corneum-piercing microprojections, and a solid coating disposed upon the microprojections, wherein the solid coating includes at least one beneficial agent and a biocompatible carrier is provided. The device is applied to the skin of a living animal (e.g., a human), causing the microprojections to pierce the stratum corneum and deliver an effective dose of the agent to the animal.
    Type: Grant
    Filed: April 20, 2002
    Date of Patent: June 21, 2011
    Assignee: Alza Corporation
    Inventors: Michel J. N. Cormier, Wendy A. Young, Juanita A. Johnson, Peter E. Daddona
  • Patent number: 7798987
    Abstract: A method and device are described for applying a microprotrusion member (44) including a plurality of microprotrusions (90) to the stratum corneum with impact. The method and device are used to improve transport of an agent across the skin for agent delivery or sampling. The applicator (10, 60, 80) causes the microprotrusion member (44) to impact the stratum corneum with a certain amount of impact determined to effectively pierce the skin with the microprotrusions (90). The preferred applicator (10, 60, 80) impacts the stratum corneum with the microprotrusion member (44) with an impact of at least 0.05 joules per cm2 of the microprotrusion member (44) in 10 msec or less.
    Type: Grant
    Filed: March 28, 2005
    Date of Patent: September 21, 2010
    Assignee: Alza Corporation
    Inventors: Joseph C. Trautman, Richard L. Keenan, Ahmad P. Samiee, WeiQi Lin, Michel J. N. Cormier, James A. Matriano, Peter E. Daddona
  • Publication number: 20100221305
    Abstract: The invention provides for a formulation for coating one or more microprojections which reduces or minimizes the loss of counterions from the coating in order to achieve a pH-stabilized formulation.
    Type: Application
    Filed: August 24, 2009
    Publication date: September 2, 2010
    Applicant: Alza Corporation
    Inventors: Mahmoud Armeri, Wei-Qi Lin, Michel J.N. Cormier, Yuh-Fun Maa
  • Patent number: 7761147
    Abstract: A transdermal electrotransport drug delivery device having an anode, a cathode and a source of electrical power electrically connected to the anode and the cathode. At least one of the anode and the cathode includes an electrode and a reservoir comprised of a housing composed of a polymeric material and an aqueous medium in contact with the housing. The aqueous medium includes (i) a drug or an electrolyte salt or a mixture thereof, (ii) propylene glycol, and (iii) an antimicrobial agent in an amount sufficient to inhibit microbial growth in the aqueous medium. The propylene glycol prevents the antimicrobial agent from being adsorbed by other materials used in the construction of the delivery device. A process for preparing a transdermal electrotransport drug delivery device is also provided.
    Type: Grant
    Filed: March 18, 2005
    Date of Patent: July 20, 2010
    Assignee: ALZA Corporation
    Inventors: Wendy A. Young, Michel J. N. Cormier
  • Publication number: 20100160895
    Abstract: An apparatus and method for transdermally delivering a biologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of microprojections (or array thereof) that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers. In one embodiment, the PTH-based agent is contained in a biocompatible coating that is applied to the microprojection member.
    Type: Application
    Filed: March 2, 2010
    Publication date: June 24, 2010
    Applicant: Alza Corporation
    Inventors: Mahmoud Ameri, Michel J.N. Cormier, Yuh-Fun Maa, Marika Kamberi, Peter E. Daddona
  • Publication number: 20100152649
    Abstract: An apparatus and method for transdermally delivering a biologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of microprojections (or array thereof) that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers. In one embodiment, the PTH-based agent is contained in a biocompatible coating that is applied to the microprojection member.
    Type: Application
    Filed: July 1, 2009
    Publication date: June 17, 2010
    Applicant: Alza Corporation
    Inventors: Mahmoud Ameri, Michel J.N. Cormier, Yuh-Fun Maa, Peter E. Daddona, Marika Kamberl