Patents by Inventor Michel J. N. Cormier
Michel J. N. Cormier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20220133627Abstract: Compositions of and methods for formulating and delivering biologically active agent formulations having enhanced physical stability, and wherein deterioration from the presence of oxygen and/or water is minimized and/or controlled, to yield a stable formulation. The compositions of and methods for formulating and delivering biologically active agents of the present invention further facilitate their incorporation into a biocompatible coating which can be employed to coat a stratum-corneum piercing microprojection, or a plurality of stratum-corneum piercing microprojections of a delivery device, for delivery of the biocompatible coating through the skin of a subject, thus providing an effective means of delivering the biologically active agents.Type: ApplicationFiled: October 15, 2021Publication date: May 5, 2022Inventors: Mahmoud Ameri, Michel J.N. Cormier, Scott Sellers, Yuh-Fun Maa
-
Patent number: 11179324Abstract: Compositions of and methods for formulating and delivering biologically active agent formulations having enhanced physical stability, and wherein deterioration from the presence of oxygen and/or water is minimized and/or controlled, to yield a stable formulation. The compositions of and methods for formulating and delivering biologically active agents of the present invention further facilitate their incorporation into a biocompatible coating which can be employed to coat a stratum-corneum piercing microprojection, or a plurality of stratum-corneum piercing microprojections of a delivery device, for delivery of the biocompatible coating through the skin of a subject, thus providing an effective means of delivering the biologically active agents.Type: GrantFiled: January 30, 2017Date of Patent: November 23, 2021Assignee: ALZA CORPORATIONInventors: Mahmoud Ameri, Michel J. N. Cormier, Scott Sellers, Yuh-Fun Maa
-
Publication number: 20170135951Abstract: Compositions of and methods for formulating and delivering biologically active agent formulations having enhanced physical stability, and wherein deterioration from the presence of oxygen and/or water is minimized and/or controlled, to yield a stable formulation. The compositions of and methods for formulating and delivering biologically active agents of the present invention further facilitate their incorporation into a biocompatible coating which can be employed to coat a stratum-corneum piercing microprojection, or a plurality of stratum-corneum piercing microprojections of a delivery device, for delivery of the biocompatible coating through the skin of a subject, thus providing an effective means of delivering the biologically active agents.Type: ApplicationFiled: January 30, 2017Publication date: May 18, 2017Inventors: Mahmoud Ameri, Michel J.N. Cormier, Scott Sellers, Yuh-Fun Maa
-
Patent number: 9573717Abstract: Compositions of and methods for formulating and delivering biologically active agent formulations having enhanced physical stability, and wherein deterioration from the presence of oxygen and/or water is minimized and/or controlled, to yield a stable formulation. The compositions of and methods for formulating and delivering biologically active agents of the present invention further facilitate their incorporation into a biocompatible coating which can be employed to coat a stratum-corneum piercing microprojection, or a plurality of stratum-corneum piercing microprojections of a delivery device, for delivery of the biocompatible coating through the skin of a subject, thus providing an effective means of delivering the biologically active agents.Type: GrantFiled: January 21, 2014Date of Patent: February 21, 2017Assignee: ALZA CORPORATIONInventors: Mahmoud Ameri, Michel J. N. Cormier, Scott Sellers, Yuh-Fun Maa
-
Publication number: 20160374955Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.Type: ApplicationFiled: September 13, 2016Publication date: December 29, 2016Applicant: ALZA CorporationInventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J.N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
-
Patent number: 9446004Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.Type: GrantFiled: May 18, 2015Date of Patent: September 20, 2016Assignee: ALZA CORPORATIONInventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J. N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
-
Patent number: 9295714Abstract: An apparatus and method for transdermally delivering a biologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of microprojections (or array thereof) that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers. In one embodiment, the PTH-based agent is contained in a biocompatible coating that is applied to the microprojection member.Type: GrantFiled: June 8, 2009Date of Patent: March 29, 2016Assignee: Alza CorporationInventors: Mahmoud Ameri, Michel J. N. Cormier, Yuh-Fun Maa, Peter E. Daddona, Marika Kamberi
-
Publication number: 20150246007Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.Type: ApplicationFiled: May 18, 2015Publication date: September 3, 2015Applicant: ALZA CorporationInventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J.N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
-
Patent number: 9056061Abstract: A transdermal nicotine salt delivery system to an individual. The system has a high nicotine salt loading to effect therapeutic flux rate. Acrylate polymeric drug reservoir with the high nicotine salt dissolved therein provides desirable adhesive characteristics and effective transdermal therapeutic properties.Type: GrantFiled: September 22, 2006Date of Patent: June 16, 2015Assignee: ALZA CorporationInventors: Robert M. Gale, Jay Audett, Rama V. Padmanabhan, Michel J. N. Cormier, Allison Luciano, Eric N. Silverberg, Paul B. Foreman
-
Patent number: 8920817Abstract: The invention provides for a formulation for coating one or more microprojections which reduces or minimizes the loss of counterions from the coating in order to achieve a pH-stabilized formulation.Type: GrantFiled: August 24, 2009Date of Patent: December 30, 2014Assignee: Alza CorporationInventors: Mahmoud Ameri, Wei-Qi Lin, Michel J. N. Cormier, Yuh-Fun Maa
-
Publication number: 20140260096Abstract: Compositions of and methods for formulating and delivering biologically active agent formulations having enhanced physical stability, and wherein deterioration from the presence of oxygen and/or water is minimized and/or controlled, to yield a stable formulation. The compositions of and methods for formulating and delivering biologically active agents of the present invention further facilitate their incorporation into a biocompatible coating which can be employed to coat a stratum-corneum piercing microprojection, or a plurality of stratum-corneum piercing microprojections of a delivery device, for delivery of the biocompatible coating through the skin of a subject, thus providing an effective means of delivering the biologically active agents.Type: ApplicationFiled: January 21, 2014Publication date: September 18, 2014Applicant: ALZA CORPORATIONInventors: Mahmoud Ameri, Michel J.N. Cormier, Scott Sellers, Yuh-Fun Maa
-
Patent number: 8663155Abstract: A device (12) and method are provided for percutaneous transdermal delivery of a potent pharmacologically active agent. The agent is dissolved in water to form an aqueous coating solution having an appropriate viscosity for coating extremely tiny skin piercing elements (10). The coating solution is applied to the skin piercing elements (10) using known coating techniques and then dried. The device (12) is applied to the skin of a living animal (e.g., a human), causing the microprotrusions (10) to pierce the stratum corneum and deliver a therapeutically effect dose of the agent to the animal.Type: GrantFiled: February 2, 2006Date of Patent: March 4, 2014Assignee: Alza CorporationInventors: Michel J. N. Cormier, Wendy A. Young, Kofi Nyam, Peter E. Daddona, Wei-Qi Lin
-
Patent number: 8632801Abstract: Compositions of and methods for formulating and delivering biologically active agent formulations having enhanced physical stability, and wherein deterioration from the presence of oxygen and/or water is minimized and/or controlled, to yield a stable formulation. The compositions of and methods for formulating and delivering biologically active agents of the present invention further facilitate their incorporation into a biocompatible coating which can be employed to coat a stratum-corneum piercing microprojection, or a plurality of stratum-corneum piercing microprojections of a delivery device, for delivery of the biocompatible coating through the skin of a subject, thus providing an effective means of delivering the biologically active agents.Type: GrantFiled: December 28, 2006Date of Patent: January 21, 2014Assignee: Alza CorporationInventors: Mahmoud Ameri, Michel J. N. Cormier, Scott Sellers, Yuh-Fun Maa
-
Patent number: 8633159Abstract: An apparatus and method for transdermally delivering a biologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of microprojections (or array thereof) that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers. In one embodiment, the PTH-based agent is contained in a biocompatible coating that is applied to the microprojection member.Type: GrantFiled: March 2, 2010Date of Patent: January 21, 2014Assignee: Alza CorporationInventors: Mahmoud Ameri, Michel J. N. Cormier, Yuh-Fun Maa, Marika Kamberi, Peter E. Daddona
-
Patent number: 8440220Abstract: A transdermal analgesic system having reduced potential for abuse, wherein the system provides for the controlled release of the antagonist at a rate sufficient to provide an abuse limiting release rate ratio of the antagonist to the analgesic when the dosage form is subject to abuse is disclosed.Type: GrantFiled: April 22, 2003Date of Patent: May 14, 2013Assignee: Durect CorporationInventors: Robert M. Gale, Thomas M. Stein, Jay Audett, Jane Stepic, Joseph B. Phipps, Michel J. N. Cormier
-
Patent number: 8361022Abstract: An apparatus and method for transdermally delivering a biologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of microprojections (or array thereof) that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers. In one embodiment, the PTH-based agent is contained in a biocompatible coating that is applied to the microprojection member.Type: GrantFiled: July 1, 2009Date of Patent: January 29, 2013Assignee: Alza CorporationInventors: Mahmoud Ameri, Michel J. N. Cormier, Yuh-Fun Maa, Peter E. Daddona, Marika Kamberl
-
Patent number: 7963935Abstract: The device including a plurality of stratum corneum-piercing microprojections, and a solid coating disposed upon the microprojections, wherein the solid coating includes at least one beneficial agent and a biocompatible carrier is provided. The device is applied to the skin of a living animal (e.g., a human), causing the microprojections to pierce the stratum corneum and deliver an effective dose of the agent to the animal.Type: GrantFiled: April 20, 2002Date of Patent: June 21, 2011Assignee: Alza CorporationInventors: Michel J. N. Cormier, Wendy A. Young, Juanita A. Johnson, Peter E. Daddona
-
Patent number: 7798987Abstract: A method and device are described for applying a microprotrusion member (44) including a plurality of microprotrusions (90) to the stratum corneum with impact. The method and device are used to improve transport of an agent across the skin for agent delivery or sampling. The applicator (10, 60, 80) causes the microprotrusion member (44) to impact the stratum corneum with a certain amount of impact determined to effectively pierce the skin with the microprotrusions (90). The preferred applicator (10, 60, 80) impacts the stratum corneum with the microprotrusion member (44) with an impact of at least 0.05 joules per cm2 of the microprotrusion member (44) in 10 msec or less.Type: GrantFiled: March 28, 2005Date of Patent: September 21, 2010Assignee: Alza CorporationInventors: Joseph C. Trautman, Richard L. Keenan, Ahmad P. Samiee, WeiQi Lin, Michel J. N. Cormier, James A. Matriano, Peter E. Daddona
-
Publication number: 20100221305Abstract: The invention provides for a formulation for coating one or more microprojections which reduces or minimizes the loss of counterions from the coating in order to achieve a pH-stabilized formulation.Type: ApplicationFiled: August 24, 2009Publication date: September 2, 2010Applicant: Alza CorporationInventors: Mahmoud Armeri, Wei-Qi Lin, Michel J.N. Cormier, Yuh-Fun Maa
-
Patent number: 7761147Abstract: A transdermal electrotransport drug delivery device having an anode, a cathode and a source of electrical power electrically connected to the anode and the cathode. At least one of the anode and the cathode includes an electrode and a reservoir comprised of a housing composed of a polymeric material and an aqueous medium in contact with the housing. The aqueous medium includes (i) a drug or an electrolyte salt or a mixture thereof, (ii) propylene glycol, and (iii) an antimicrobial agent in an amount sufficient to inhibit microbial growth in the aqueous medium. The propylene glycol prevents the antimicrobial agent from being adsorbed by other materials used in the construction of the delivery device. A process for preparing a transdermal electrotransport drug delivery device is also provided.Type: GrantFiled: March 18, 2005Date of Patent: July 20, 2010Assignee: ALZA CorporationInventors: Wendy A. Young, Michel J. N. Cormier