Patents by Inventor Michel Klich

Michel Klich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS, IN PARTICULAR AS ANTIBACTERIALS AND BETA-LACTAMASE INHIBITORS
    Publication number: 20090018329
    Abstract: The invention relates to novel heterocyclic compounds of general formula (I), and their salts with a base or an acid: The invention also relates to a method for preparing these compounds, and to their use as medicaments, in particular as antibacterials and ?-lactamase inhibitors.
    Type: Application
    Filed: September 16, 2008
    Publication date: January 15, 2009
    Applicant: Novexel
    Inventors: Maxime Lampilas, Branislav Musicki, Michel Klich, David Allen Rowlands
  • Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
    Patent number: 7439253
    Abstract: The invention relates to novel heterocyclic compounds of general formula (I), and their salts with a base or an acid: The invention also relates to a method for preparing these compounds, and to their use as medicaments, in particular as antibacterials and ?-lactamase inhibitors.
    Type: Grant
    Filed: December 4, 2003
    Date of Patent: October 21, 2008
    Assignee: Novexel
    Inventors: Maxime Lampilas, Branislav Musicki, Michel Klich, David Alan Rowlands
  • Aromatic derivatives substituted by a ribose, their preparation process and their use as medicaments
    Patent number: 6812331
    Abstract: A subject of the invention is the compounds of formula (I): R1═H, OH, alkyl, alkenyl or alkynyl optionally substituted or alkoxy, R2═H, Hal, R3═H, alkyl, Hal,  Rg and Rh: H, alkyl, aryl heterocycle, R5═H or O-alkyl, R6═alkyl or CH2—O-alkyl, R7═H or alkyl. The compounds of formula (I) have antibiotic properties.
    Type: Grant
    Filed: June 7, 2001
    Date of Patent: November 2, 2004
    Assignee: Aventis Pharma S.A.
    Inventors: Michel Klich, Patrick Laurin, Branislav Musicki, Laurent Schio
  • Novel heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
    Publication number: 20040157826
    Abstract: The invention relates to novel heterocyclic compounds of general formula (I), and their salts with a base or an acid: 1
    Type: Application
    Filed: December 4, 2003
    Publication date: August 12, 2004
    Applicant: AVENTIS PHARMA S.A.
    Inventors: Maxime Lampilas, Branislav Musicki, Michel Klich, David Alan Rowlands
  • Aromatic amides, preparation method and application as medicines
    Patent number: 6583119
    Abstract: The invention relates to aromatic amides of formula wherein the various substituents are defined as set forth in the specification which have antibiotic activity.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: June 24, 2003
    Assignee: Aventis Pharma S.A.
    Inventors: Jean-Luc Haesslein, Michel Klich, Patrick Laurin, Branislav Musicki, Anne-Marie Periers
  • Ribose-substituted aromatic amides, method for the production and use thereof as medicaments
    Patent number: 6579902
    Abstract: Compounds of formula (I); wherein R1=alkyl, alkenyl or alkynyl, O-alkyl, O-alkenyl or optionally substituted, optionally interrupted O-alkynyl; R2=hydrogen or halogen; R3=hydrogen, alkyl or halogen; R4=NHR′ or NHOR″, R′ or R″ are identical or different and represent hydrogen, alkyl, alkenyl or alkynyl, aryl; R5=hydrogen or O-alkyl; R6=alkyl or CH2—O-alkyl; R7=hydrogen or alkyl or R6 et R7 form a cycle together with the carbon carrying them in addition to the addition salts thereof with bases. The compounds of formula (I) have antibiotic properties.
    Type: Grant
    Filed: January 9, 2002
    Date of Patent: June 17, 2003
    Assignee: Aventis Pharma S.A.
    Inventors: Jacques Demassey, Michel Klich, Branislav Musicki
  • Novel aromatic amides, preparation method and application as medicines
    Publication number: 20030060609
    Abstract: The invention concerns compounds of formula (I), in which Y is oxygen, N-Nalc 1 or NOalc 2: X represents hydrogen, hydroxyl, alkyl, alkenyl, alkynyl, alkoxy, CONOR or NRcRd, Rc and Rd being hydrogen or alkyl; Z represents hydrogen, halogen or free, etherified or esterified OH; R 2 hydrogen or halogen; R 3 hydrogen, alkyl or halogen; R hydrogen or alkyl; R 1 hydrogen, alkyl, alkenyl or alkynyl; R 5 hydrogen or O-alkyl; R 6 alkyl or CH 2 —O-alkyl and R 7 hydrogen or alkyl; or R 6 and R 7 form with the carbon atom which bears them a cyclic radical containing up to 8 carbon atoms. The compounds of formula (I) have antibiotic properties.
    Type: Application
    Filed: June 5, 2002
    Publication date: March 27, 2003
    Applicant: Aventis Pharma S.A.
    Inventors: Jean-Luc Haesslein, Michel Klich, Patrick Laurin, Branislav Musicki, Anne-Marie Periers
  • Aromatic amides, preparation method and application as medicines
    Patent number: 6420538
    Abstract: A compound having a formula wherein the substituents are defined as in the specification and its non-toxic, pharmaceutically acceptable acid addition salts which are useful as antibiotics.
    Type: Grant
    Filed: August 30, 2000
    Date of Patent: July 16, 2002
    Assignee: Aventis Pharma S.A.
    Inventors: Jean-Luc Haesslein, Michel Klich, Patrick Laurin, Branislav Musicki, Anne-Marie Periers
  • Aromatic derivatives substituted by a ribose, their method of preparation and application as medicine
    Patent number: 6350733
    Abstract: A subject of the invention is the compounds of formula (I): R1=H, OH, alkyl, alkenyl or alkynyl optionally substituted or alkoxy, R2=H, Hal, R3=H, alkyl, Hal, Rg and Rh: H, alkyl, aryl heterocycle, R5=H or O-alkyl, R6=alkyl or CH2—O-alkyl, R7=H or alkyl. The compounds of formula (I) have antibiotic properties.
    Type: Grant
    Filed: December 21, 1998
    Date of Patent: February 26, 2002
    Assignee: Aventis Pharma S.A.
    Inventors: Michel Klich, Patrick Laurin, Branislav Musicki, Laurent Schio
  • New aromatic derivatives substituted by a ribose, their preparation process and their use as medicaments
    Publication number: 20020010322
    Abstract: A subject of the invention is the compounds of formula (I): 1
    Type: Application
    Filed: June 7, 2001
    Publication date: January 24, 2002
    Applicant: Aventis Pharma S.A.
    Inventors: Michel Klich, Patrick Laurin, Branislav Musicki, Laurent Schio
  • Aromatic derivatives substituted by a ribose, their preparation process and their use as medicaments
    Patent number: 5968939
    Abstract: A subject of the invention is the compounds of formula (I): ##STR1## having antibiotic properties.
    Type: Grant
    Filed: July 22, 1998
    Date of Patent: October 19, 1999
    Assignee: Hoechst Marion Roussel
    Inventors: Fabienne Chatreaux, Michel Klich, Laurent Schio
  • Novel 11 .beta.-alkynylphenyl-10-nor-steroids
    Patent number: 4912097
    Abstract: Novel 11.beta.-alkynylphenyl-19-nor-steroids of the formula ##STR1## wherein R.sub.1 is alkynyl of 2 to 8 carbon atoms optionally substituted with at least one member of the group consisting of --OH halogen, trialkylsilyl of 1 to 6 alkyl carbon atoms, alkoxy and alkylthio of 1 to 6 carbon atoms and dialkylamino of 1 to 6 alkyl carbon atoms having remarkably antiprogestomimetic and antiglucocorticoidal activity.
    Type: Grant
    Filed: April 30, 1987
    Date of Patent: March 27, 1990
    Assignee: Roussel Uclaf
    Inventors: Jean-Georges Teutsch, Michel Klich, Daniel Philibert