Patents by Inventor Michel Kohl

Michel Kohl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conjugates of haptens to beta-lactam derivatives and their use for detecting and/or quantifying haptens in solution and device for implementation thereof
    Publication number: 20040157262
    Abstract: The present invention is related to a conjugate of a hapten to a natural or synthetic &bgr;-lactam derivative, comprising at least a side chain, wherein the side chain of the &bgr;-lactam derivative is at least partially constitutive of the conjugating arm.
    Type: Application
    Filed: July 25, 2001
    Publication date: August 12, 2004
    Inventors: Michel Kohl, Roger Renotte, Guy Sarlet, Robert Lejeune, Benoit Granier
  • Conjugates of haptens to beta-lactam derivatives and their use for detecting and/or quantifying haptens in solution and device for implementation thereof
    Publication number: 20030235877
    Abstract: The present invention is related to a conjugate of a hapten to a natural or synthetic &bgr;-lactam derivative, comprising at least a side chain, wherein the side chain of the &bgr;-lactam derivative is at least partially constitutive of the conjugating arm.
    Type: Application
    Filed: October 10, 2002
    Publication date: December 25, 2003
    Applicant: La Region Wallone
    Inventors: Michel Kohl, Roger Renotte, Guy Sarlet, Robert Lejeune, Benoit Granier
  • Method for detecting and/or quantifying a hapten in a homogeneous phase and device for implementation thereof
    Patent number: 6436649
    Abstract: The invention discloses a method for detecting and/or quantifying a hapten in a homogeneous phase, comprising the following steps: adding a known quantity of a hapten inhibitor complex to the solution containing the hapten to be detected and/or quantified; adding to the solution a quantity of antibodies corresponding to the quantity of the hapten/inhibitor complex; adding to the solution a type C &bgr;-lactamase having an active site for two substrates in antigenic competition in the said active site, the first substrate being a reporter substrate capable of being transformed into a detectable and/or quantifiable product, preferably by visible UV radiation measurement, the second substrate being the hapten/inhibitor complex acting on the hydrolysis rate of the reporter substrate; detecting and/or quantifying the concentration of the product resulting from the transformation of the reporter substrate, the Km constant of the reporter substrate being at least a hundred times higher than the Km constant of the ha
    Type: Grant
    Filed: June 11, 1999
    Date of Patent: August 20, 2002
    Assignee: Le Region Wallone
    Inventors: Michel Kohl, Roger Renotte, Gianangelo Ghitti, Guy Sarlet, Robert Lejeune