Patents by Inventor Michel Labuschagne

Michel Labuschagne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of Obtaining Optically Active Epoxides and Vicinal Diols from Styrene Oxides
    Publication number: 20090275077
    Abstract: The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific meso-epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vectors containing such nucleic acid molecules, and cells containing such vectors. Also embraced by the invention are methods for obtaining containing such nucleic acid molecules, and cells containing such vectors.
    Type: Application
    Filed: February 17, 2009
    Publication date: November 5, 2009
    Applicant: Oxyrane (UK) Limited
    Inventors: Adriana Leonora Botes, Jeanette Lotter, Michel Labuschagne, Robin Kumar Mitra
  • Methods for Obtaining Optically Active Glycidyl Ethers and Optically Active Vicinal Diols from Racemic Substrates
    Publication number: 20080213833
    Abstract: The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific glycidyl ether hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vectors containing such nucleic acid molecules, and cells containing such vectors. Also embraced by the invention are methods for obtaining optically active glycidyl ethers and associated optically active vicinal diols.
    Type: Application
    Filed: October 15, 2007
    Publication date: September 4, 2008
    Applicant: Oxrane (UK) Ltd.
    Inventors: Adriana Leonora Botes, Michel Labuschagne, Jeanette Lotter, Robin Kumar Mitra
  • Methods for Obtaining Optically Active Epoxides and Diols from 2,3-Disubstituted and 2,3-Trisubstituted Epoxides
    Publication number: 20080199912
    Abstract: The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific internal epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vectors containing such nucleic acid molecules, and cells containing such vectors. Also embraced by the invention are methods for obtaining optically active internal epoxides and corresponding optically active internal diols.
    Type: Application
    Filed: October 15, 2007
    Publication date: August 21, 2008
    Applicant: Oxyrane (UK) Ltd.
    Inventors: Adriana Leonora Botes, Jeanette Lotter, Michel Labuschagne, Robin Kumar Mitra, Robyn Roth, Nasreen Abrahams, Clinton Simpson, Christiaan Van Der Westhuyzen
  • Recombinant Yeasts for Synthesizing Epoxide Hydrolases
    Publication number: 20080171359
    Abstract: The invention provides isolated Y. lipolytica cells and substantially pure cultures of Y. lipolytica cells containing exogenous nucleic acids encoding EH polypeptides, e.g., enantioselective EH polypeptides. Also featured by the invention are methods for the production of the EH polypeptides and methods for hydrolysing epoxides and for producing optically active vicinal diols and/or optically active epoxides. Also embodied by the invention are efficient integrative expression vectors.
    Type: Application
    Filed: October 15, 2007
    Publication date: July 17, 2008
    Applicant: Oxyrane (UK) Ltd.
    Inventors: Adriana Leonora Botes, Michel Labuschagne, Robyn Roth, Robin Kumar Mitra, Jeanette Lotter, Rajesh Lalloo, Deepak Ramduth, Neeresh Rohitlall, Clinton Simpson, Petrus Van Zyl
  • Methods For Obtaining Optically Active Epoxides and Vicinal Diols From Styrene Oxides
    Publication number: 20070281339
    Abstract: The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific styrene epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vectors containing such nucleic acid molecules, and cells containing such vectors. Also embraced by the invention are methods for obtaining optically active styrene vicinal diols and optically active styrene epoxides.
    Type: Application
    Filed: April 18, 2005
    Publication date: December 6, 2007
    Inventors: Adriana Botes, Jeannette Lotter, Michel Labuschagne, Robin Mitra
  • Methods For Obtaining Optically Active Epoxides And Vicinal Diols From Meso-Epoxides
    Publication number: 20070275448
    Abstract: The invention provides yeast strains, and polypeptides encoded by genes of such yeast strains, that have enantiospecific meso-epoxide hydrolase activity. The invention also features nucleic acid molecules encoding such polypeptides, vectors containing such nucleic acid molecules, and cells containing such vectors. Also embraced by the invention are methods for obtaining optically active vicinal diols from meso-epoxides.
    Type: Application
    Filed: April 18, 2005
    Publication date: November 29, 2007
    Applicant: CSIR
    Inventors: Adriana Botes, Jeanette Lotter, Michel Labuschagne