Patents by Inventor Michel Leonetti

Michel Leonetti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Molecular Complex for Targeting Antigens Towards Cells Comprising Antigens and Uses Thereof for Vaccination
    Publication number: 20190322731
    Abstract: The invention relates to a molecular complex for targeting the antigen towards cells comprising antigens, including at least one antigen associated with at least two ligands of surface molecules of cells comprising antigens, said complex including at least one first ligand of a sulphated sugar of the glycosaminoglycan family and a second ligand of a specific surface molecule of cells comprising antigens, and said first ligand being covalently bonded with said antigen and/or said second ligand.
    Type: Application
    Filed: July 3, 2019
    Publication date: October 24, 2019
    Applicant: Commissariat a l'Energie Atomique et aux Energies Alternatives
    Inventors: Michel Leonetti, Alexandra Savatier, Adeline Gadzinski, Jean-Claude Boulain
  • Molecular complex for targeting antigens towards cells comprising antigens and uses thereof for vaccination
    Patent number: 10385120
    Abstract: The invention relates to a molecular complex for targeting the antigen towards cells comprising antigens, including at least one antigen associated with at least two ligands of surface molecules of cells comprising antigens, said complex including at least one first ligand of a sulphated sugar of the glycosaminoglycan family and a second ligand of a specific surface molecule of cells comprising antigens, and said first ligand being covalently bonded with said antigen and/or said second ligand.
    Type: Grant
    Filed: February 1, 2011
    Date of Patent: August 20, 2019
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Michel Leonetti, Alexandra Savatier, Adeline Gadzinski, Jean-Claude Boulain
  • Method for obtaining antigen-specific human antibodies by in vitro immunisation
    Patent number: 9816072
    Abstract: A method for the in vitro immunization of human B lymphocytes, comprising culturing a total mononuclear cell population of human peripheral blood in the presence of an antigenic composition comprising at least one antigen covalently bonded to both: (i) a Tat protein or a Tat fragment capable of oligomerization and (ii) a ligand of a surface molecule specific to the antigen presenting cells; a method for producing antigen-specific human antibodies derived from said in vitro immunization method.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: November 14, 2017
    Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Michel Leonetti, Patricia Lamourette, Herve Volland, Alexandra Savatier, Anne Wijkhuisen
  • METHOD FOR OBTAINING ANTIGEN-SPECIFIC HUMAN ANTIBODIES BY IN VITRO IMMUNISATION
    Publication number: 20150299655
    Abstract: A method for the in vitro immunisation of human B lymphocytes, comprising culturing a total mononuclear cell population of human peripheral blood in the presence of an antigenic composition comprising at least one antigen covalently bonded to both: (i) a Tat protein or a Tat fragment capable of oligomerisation and (ii) a ligand of a surface molecule specific to the antigen presenting cells; a method for producing antigen-specific human antibodies derived from said in vitro immunisation method.
    Type: Application
    Filed: November 26, 2013
    Publication date: October 22, 2015
    Inventors: Michel LEONETTI, Patricia LAMOURETTE, Herve VOLLAND, Alexandra SAVATIER, Anne WIJKHUISEN
  • Stabilized Tat antigen and the use thereof for anti-HIV vaccination
    Patent number: 8501193
    Abstract: The invention relates to a vaccine composition comprising at least one type of anti-HIV vaccine composition containing at least one type of stabilized Tat antigen and to the use thereof for preventing and/or treating a human HIV infection.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: August 6, 2013
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Pascal Drevet, Evelyne Lajeunesse, Alain Lecoq, Michel Leonetti, André Menez, Gervaise Moine, Robert Thai
  • Molecular Complex for Targeting Antigens Towards Cells Comprising Antigens and Uses Thereof for Vaccination
    Publication number: 20130195908
    Abstract: The invention relates to a molecular complex for targeting the antigen towards cells comprising antigens, including at least one antigen associated with at least two ligands of surface molecules of cells comprising antigens, said complex including at least one first ligand of a sulphated sugar of the glycosaminoglycan family and a second ligand of a specific surface molecule of cells comprising antigens, and said first ligand being covalently bonded with said antigen and/or said second ligand.
    Type: Application
    Filed: February 1, 2011
    Publication date: August 1, 2013
    Inventors: Michel Leonetti, Alexandra Savatier, Adeline Gadzinski, Jean-Claude Boulain