Patents by Inventor Michel Level

Michel Level has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipophile derivatives of muramylpeptides having properties of activating macrophages and compositions containing them
    Patent number: 4939122
    Abstract: The invention relates to muramyleptide derivatives resulting essentially from the conjugation or the coupling, as the case may require, through an arm, between a muramylpeptide and a group containing two atoms contiguous with one another to each of which is attached a lipophile chain comprising from 8 to 100 carbon atoms, preferably from 14 to 24 carbon atoms. The derivatives according to the invention are endowed with remarkable stimulating properties with respect to the activation of macrophages, of which they amplify the tumoricidal properties.
    Type: Grant
    Filed: June 9, 1988
    Date of Patent: July 3, 1990
    Assignee: Agence Nationale de Valorisation de la Recherche (ANVAR)
    Inventors: Nigel Phillips, Francoise Audibert, Jean-Marie Bernard, Louis Chedid, Pierre Lefrancier, Michel Level, Monique Parant
  • Conjugates of haptenes and muramyl-peptides, endowed with immunogenic activity and compositions containing them
    Patent number: 4639512
    Abstract: The invention relates to an immunogenic principle containing a specific antigen determinant of a predetermined native antigen. This immunogenic principle is constituted by a conjugate between a hapten bearing said antigenic site and a muramyl-peptide, essentially in the absence of supporting macromolecules, this conjugate having an immunogenic effect not only against itself, but also with respect to the native antigen carrying said antigenic site.
    Type: Grant
    Filed: March 11, 1983
    Date of Patent: January 27, 1987
    Assignee: Agence Nationale de Valorisation de la Recherche
    Inventors: Francoise Audibert, Claude Carelli, Louis Chedid, Pierre LeFrancier, Michel Level, Jean Choay
  • Lipophila derivatives of muramylpeptides having properties of activating macrophages and compositions containing them
    Patent number: RE35706
    Abstract: The invention relates to muramyleptide derivatives resulting essentially from the conjugation or the coupling, as the case may require, through an arm, between a muramylpeptide and a group containing two atoms contiguous with one another to each of which is attached a lipophile chain comprising from 8 to 100 carbon atoms, preferably from 14 to 24 carbon atoms. The derivatives according to the invention are endowed with remarkable stimulating properties with respect to the activation of macrophages, of which they amplify the tumoricidal properties.
    Type: Grant
    Filed: October 25, 1994
    Date of Patent: December 30, 1997
    Assignee: VACSYN Inc.
    Inventors: Nigel Phillips, Fran.cedilla.oise Audibert, Jean-Marie Bernard, Louis Chedid, Pierre Lefrancier, Michel Level, Monique Parant