Patents by Inventor Michel Lopez

Michel Lopez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240141375
    Abstract: Provided are compositions and methods for transducing immune cells in vivo where a viral particle comprising a polynucleotide encoding a chimeric antigen receptor and a multipartite cell-surface receptor is administered to a subject.
    Type: Application
    Filed: January 26, 2022
    Publication date: May 2, 2024
    Inventors: Andrew Scharenberg, Christopher Nicolai, Ryan Crisman, Alessandra Sullivan, Kathryn Michels, Byoung Ryu, Shon Green, Laurie Beitz, Susana Hernandez Lopez
  • Patent number: 11623882
    Abstract: The invention relates to a method and device for clarifying water by means treatment of the colloidal structures contained in a liquid and/or a sludge supplied in a continuous flow at a flow rate of QEB=VEB/hour. The flow is sprayed into a chamber under overpressure conditions in relation to atmospheric pressure, said chamber having a volume v<VEB/20, and air being injected simultaneously therein at a flow rate d.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: April 11, 2023
    Assignee: Orege
    Inventors: Patrice Capeau, Michel Lopez, Pascal Gendrot
  • Patent number: 11319516
    Abstract: The present invention relates to the use of a cysteine endoprotease or a malt extract to prevent or reduce the cloudiness of a cereal-based beverage, fermented or not.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: May 3, 2022
    Assignees: MALTERIES SOUFFLET, INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE. L'ALIMENTATION ET L'ENVIRONNEMENT
    Inventors: Michel Lopez, Myriam Fliss, Didier Gilbert Marion
  • Patent number: 10167346
    Abstract: Compositions for improving the health of a subject comprise alpha-(1,2)-branched alpha-(1,6) oligodextrans, preferably with an average molecular weight between about 10 kDa and 70 kDa, between about 10% and 50% alpha-(1,2)-osidic side chains, and having at least partial indigestibility in the subject. Methods for improving the health of a subject comprise administering the composition to a subject in an amount effective to improve gut health, or to prevent or treat a gastrointestinal disorder, a cholesterol-related disorder, diabetes, or obesity. Methods for making oligodextrans having controlled size and controlled degree of branching comprise providing alpha-(1,6) oligodextrans having an average molecular weight between 0.5 and 100 kDa and introducing at least 10% alpha-(1,2)-osidic side chains onto the alpha-(1,6) oligodextrans.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: January 1, 2019
    Assignee: Tate & Lyle Ingredients France SAS
    Inventors: Thierry Naeye, Alexandra Einerhand, Michel Lopez, Susan M. Potter, Magali Remaud-Siméon, Pierre Frédéric Emmanuel Monsan
  • Publication number: 20180327289
    Abstract: The invention relates to a method and device for clarifying water by means treatment of the colloidal structures contained in a liquid and/or a sludge supplied in a continuous flow at a flow rate of QEB=VEB/hour. The flow is sprayed into a chamber under overpressure conditions in relation to atmospheric pressure, said chamber having a volume v<VEB/20, and air being injected simultaneously therein at a flow rate d.
    Type: Application
    Filed: July 20, 2018
    Publication date: November 15, 2018
    Inventors: Patrice Capeau, Michel Lopez, Pascal Gendrot
  • Patent number: 10029930
    Abstract: The invention relates to a method and device for clarifying water by means treatment of the colloidal structures contained in a liquid and/or a sludge supplied in a continuous flow at a flow rate of QEB=VEB/hour. The flow is sprayed into a chamber (2) under overpressure conditions in relation to atmospheric pressure, said chamber (2) having a volume v<VEB/20, and air (10) being injected simultaneously therein at a flow rate d.
    Type: Grant
    Filed: October 28, 2011
    Date of Patent: July 24, 2018
    Assignee: Orege
    Inventors: Patrice Capeau, Michel Lopez, Pascal Gendrot
  • Publication number: 20180170785
    Abstract: The invention relates to a method for separating the liquid part from the suspended matter in a sludge supplied in a continuous flow at a flow rate of QEB=V/hour. The flow is divided into at least two partial flows which are sprayed on top of one another into a sealed chamber of volume v<V/20, simultaneously injecting air therein at a flow rate d, said chamber being kept under overpressure conditions. The suspended matter of the thus treated flow is then left to decant in a collection container, with the cake or solid part falling to the bottom and separating from the liquid part which is continuously discharged.
    Type: Application
    Filed: January 5, 2018
    Publication date: June 21, 2018
    Inventors: Patrice Capeau, Michel Lopez, Pascal Gendrot
  • Publication number: 20180112158
    Abstract: The present invention relates to the use of a cysteine endoprotease or a malt extract to prevent or reduce the cloudiness of a cereal-based beverage, fermented or not.
    Type: Application
    Filed: April 29, 2016
    Publication date: April 26, 2018
    Applicants: MALTERIES SOUFFLET, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA)
    Inventors: Michel LOPEZ, Myriam FLISS, Didier Gilbert MARION
  • Patent number: 9890068
    Abstract: The invention relates to a method for separating the liquid part from the suspended matter in a sludge supplied in a continuous flow at a flow rate of QEB=V/hour. The flow is divided into at least two partial flows which are sprayed on top of one another into a sealed chamber of volume v<V/20, simultaneously injecting air therein at a flow rate d, said chamber being kept under overpressure conditions. The suspended matter of the thus treated flow is then left to decant in a collection container, with the cake or solid part falling to the bottom and separating from the liquid part which is continuously discharged.
    Type: Grant
    Filed: October 28, 2011
    Date of Patent: February 13, 2018
    Assignee: Orege
    Inventors: Patrice Capeau, Michel Lopez, Pascal Gendrot
  • Publication number: 20170101484
    Abstract: Compositions for improving the health of a subject comprise alpha-(1,2)-branched alpha-(1,6) oligodextrans, preferably with an average molecular weight between about 10 kDa and 70 kDa, between about 10% and 50% alpha-(1,2)-osidic side chains, and having at least partial indigestibility in the subject. Methods for improving the health of a subject comprise administering the composition to a subject in an amount effective to improve gut health, or to prevent or treat a gastrointestinal disorder, a cholesterol-related disorder, diabetes, or obesity. Methods for making oligodextrans having controlled size and controlled degree of branching comprise providing alpha-(1,6) oligodextrans having an average molecular weight between 0.5 and 100 kDa and introducing at least 10% alpha-(1,2)-osidic side chains onto the alpha-(1,6) oligodextrans.
    Type: Application
    Filed: October 21, 2016
    Publication date: April 13, 2017
    Applicant: TATE & LYLE INGREDIENTS FRANCE SAS
    Inventors: THIERRY NAEYE, ALEXANDRA EINERHAND, MICHEL LOPEZ, SUSAN M. POTTER, MAGALI REMAUD-SIMÉON, PIERRE FRÉDÉRIC EMMANUEL MONSAN
  • Patent number: 9512239
    Abstract: Compositions for improving the health of a subject comprise alpha-(1,2)-branched alpha-(1,6) oligodextrans, preferably with an average molecular weight between about 10 kDa and 70 kDa, between about 10% and 50% alpha-(1,2)-osidic side chains, and having at least partial indigestibility in the subject. Methods for improving the health of a subject comprise administering the composition to a subject in an amount effective to improve gut health, or to prevent or treat a gastrointestinal disorder, a cholesterol-related disorder, diabetes, or obesity. Methods for making oligodextrans having controlled size and controlled degree of branching comprise providing alpha-(1,6) oligodextrans having an average molecular weight between 0.5 and 100 kDa and introducing at least 10% alpha-(1,2)-osidic side chains onto the alpha-(1,6) oligodextrans.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: December 6, 2016
    Assignee: TATE & LYLE INGREDIENTS FRANCE SAS
    Inventors: Thierry Naeye, Alexandra Einerhand, Michel Lopez, Susan M. Potter, Magali Remaud-Siméon, Pierre Frédéric Emmanuel Monsan
  • Patent number: 8927044
    Abstract: A bakery product comprises white chocolate in the form of one or more discrete pieces, wherein the white chocolate comprises an effective amount of fiber to reduce shape deformation and/or browning of the white chocolate during the production of the bakery product.
    Type: Grant
    Filed: November 25, 2008
    Date of Patent: January 6, 2015
    Assignee: Barry Callebaut AG
    Inventors: Michel Lopez, An Parrein, Valentine Detalle
  • Publication number: 20150004140
    Abstract: Compositions for improving the health of a subject comprise alpha-(1,2)-branched alpha-(1,6) oligodextrans, preferably with an average molecular weight between about 10 kDa and 70 kDa, between about 10% and 50% alpha-(1,2)-osidic side chains, and having at least partial indigestibility in the subject. Methods for improving the health of a subject comprise administering the composition to a subject in an amount effective to improve gut health, or to prevent or treat a gastrointestinal disorder, a cholesterol-related disorder, diabetes, or obesity. Methods for making oligodextrans having controlled size and controlled degree of branching comprise providing alpha-(1,6) oligodextrans having an average molecular weight between 0.5 and 100 kDa and introducing at least 10% alpha-(1,2)-osidic side chains onto the alpha-(1,6) oligodextrans.
    Type: Application
    Filed: July 11, 2014
    Publication date: January 1, 2015
    Inventors: Thierry NAEYE, Alexandra Eilnerhand, Michel Lopez, Susan M. Potter, Magali Remaud-Siméon, Pierre Frédéric Emmanuel Monsan
  • Patent number: 8816067
    Abstract: Compositions for improving the health of a subject comprise alpha-(1,2)-branched alpha-(1,6) oligodextrans, preferably with an average molecular weight between about 10 kDa and 70 kDa, between about 10% and 50% alpha-(1,2)-osidic side chains, and having at least partial indigestibility in the subject. Methods for improving the health of a subject comprise administering the composition to a subject in an amount effective to improve gut health, or to prevent or treat a gastrointestinal disorder, a cholesterol-related disorder, diabetes, or obesity. Methods for making oligodextrans having controlled size and controlled degree of branching comprise providing alpha-(1,6) oligodextrans having an average molecular weight between 0.5 and 100 kDa and introducing at least 10% alpha-(1,2)-osidic side chains onto the alpha-(1,6) oligodextrans.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: August 26, 2014
    Assignee: Tate & Lyle Ingredients France SAS
    Inventors: Thierry Naeye, Alexandra Einerhand, Michel Lopez, Susan M. Potter, Magali Remaud-Siméon, Pierre Frédéric Emmanuel Monsan
  • Publication number: 20130227997
    Abstract: The invention relates to a method for separating the liquid part from the suspended matter in a sludge supplied in a continuous flow at a flow rate of QEB=V/hour. The flow is divided into at least two partial flows which are sprayed on top of one another into a sealed chamber of volume v<V/20, simultaneously injecting air therein at a flow rate d, said chamber being kept under overpressure conditions. The suspended matter of the thus treated flow is then left to decant in a collection container, with the cake or solid part falling to the bottom and separating from the liquid part which is continuously discharged.
    Type: Application
    Filed: October 28, 2011
    Publication date: September 5, 2013
    Applicant: OREGE
    Inventors: Patrice Capeau, Michel Lopez, Pascal Gendrot
  • Publication number: 20130220937
    Abstract: The invention relates to a method and device for clarifying water by means treatment of the colloidal structures contained in a liquid and/or a sludge supplied in a continuous flow at a flow rate of QEB=VEB/hour. The flow is sprayed into a chamber (2) under overpressure conditions in relation to atmospheric pressure, said chamber (2) having a volume v<VEB/20, and air (10) being injected simultaneously therein at a flow rate d.
    Type: Application
    Filed: October 28, 2011
    Publication date: August 29, 2013
    Applicant: OREGE
    Inventors: Patrice Capeau, Michel Lopez, Pascal Gendrot
  • Patent number: 8366938
    Abstract: The invention relates to a method and a device for purifying liquid effluents, in which water is separated from substances by performing, in a single vertical enclosure (3), a vertical bubbling in the effluents fed at a flow rate d. The enclosure has a free surface and includes at least two compartments (4, 5, 6, 7) communicating together for enabling a circulation between the compartments successively from the top to the bottom and from the bottom to the top between the lower portion thereof and a medium level at a flow rate D at least three times higher than the flow rate d. The supernatant phase is continuously discharged and a hydraulic or gaseous chemical oxidation of said effluents is simultaneously carried out in the same enclosure, the chemical oxidation rate and the bubble flow rate and size being selected in order to progressively obtain a separation of the solid/liquid and liquid/liquid phases at the surface of the enclosure for obtaining a COD below a predetermined threshold.
    Type: Grant
    Filed: April 14, 2008
    Date of Patent: February 5, 2013
    Assignee: Orege, Societe a Responsabilite Limitee
    Inventors: Patrice Capeau, Michel Lopez, Pascal Gendrot
  • Patent number: 8257760
    Abstract: The invention relates to a method for the prevention or reduction of haze in a beverage by the addition of a prolyl-specific and/or alamine specific endoprotease and the new beverages obtainable by the method according to the invention. It also relates to new endoproteases. It also relates to methods as described above wherein auxiliary enzymes are used in combination with the specific endoprotease. Sequence information of a genomic DNA, cDNA as well as protein sequences are provided.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: September 4, 2012
    Assignee: DSM IP Assets B.V.
    Inventors: Luppo Edens, Michel Lopez
  • Publication number: 20120141628
    Abstract: The invention relates to a method for the prevention or reduction of haze in a beverage by the addition of an prolyl-specific endoprotease and to new beverages obtainable by the method according to the invention. It also relates to new endoproteases. Sequence information of a genomic DNA, cDNA as well as protein sequences.
    Type: Application
    Filed: January 13, 2012
    Publication date: June 7, 2012
    Applicant: DSM IP Assets B.V.
    Inventors: Michel LOPEZ, Luppo Edens
  • Publication number: 20120043224
    Abstract: The invention relates to a method and to a device for scrubbing liquid effluents laden with dissolved or undissolved organic and/or inorganic substances and continuously fed at a flow rate Df. After a preliminary effluent-floating operation if required, the method comprises carrying out at least one treatment cycle, the treatment cycle including a first step in which the effluents are subjected to an electrolytic treatment by circulation in a first compartment while generating a very strong turbulence, followed by a second step in which the undissolved elements contained in the effluents are agglomerated by coagulation/flocculation before circulating the effluents in a second free surface compartment, with the scraping of the sludge carried out at the upper portion, while bubbling and maintaining a reduced turbulence in said second compartment.
    Type: Application
    Filed: February 16, 2010
    Publication date: February 23, 2012
    Applicant: OREGE
    Inventors: Michel Lopez, Patrice Capeau, Pascal Gendrot