Patents by Inventor Michel M. Afargan

Michel M. Afargan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conformationally constrained backbone cyclized somatostatin analogs
    Patent number: 7060679
    Abstract: Methods of use of pharmaceutical compositions and novel peptides which are conformationally constrained backbone cyclized somatostatin analogs, having somatostatin receptor subtype selectivity, are disclosed. These patterns or receptor subtype selectivity provide compounds having improved therapeutic utility. Methods for synthesizing the somatostatin analogs and for screening of the somatostatin analogs are also disclosed. Furthermore, pharmaceutical compositions comprising somatostatin analogs are disclosed.
    Type: Grant
    Filed: August 12, 2004
    Date of Patent: June 13, 2006
    Assignee: DeveloGen Israel Ltd.
    Inventors: Vered Hornik, Michel M. Afargan, Gary Gellerman
  • Conformationally constrained backbone cyclized somatostatin analogs
    Patent number: 6930088
    Abstract: Novel peptides which are conformationally constrained backbone cyclized somatostatin analogs, having somatostatin receptor subtype selectivity are disclosed. These patterns or receptor subtype selectivity provide compounds having improved therapeutic utility. Methods for synthesizing the somatostatin analogs and for screening of the somatostatin analogs are also disclosed. Furthermore, pharmaceutical compositions comprising somatostatin analogs, and methods of using such compositions are disclosed.
    Type: Grant
    Filed: December 13, 2000
    Date of Patent: August 16, 2005
    Assignee: Peptor Ltd.
    Inventors: Vered Hornik, Michel M. Afargan, Gary Gellerman
  • Conformationally constrained backbone cyclized somatostatin analogs
    Publication number: 20020052315
    Abstract: Novel peptides which are conformationally constrained backbone cyclized somatostatin analogs, having somatostatin receptor subtype selectivity are disclosed. These patterns or receptor subtype selectivity provide compounds having improved therapeutic utility. Methods for synthesizing the somatostatin analogs and for screening of the somatostatin analogs are also disclosed. Furthermore, pharmaceutical compositions comprising somatostatin analogs, and methods of using such compositions are disclosed.
    Type: Application
    Filed: December 13, 2000
    Publication date: May 2, 2002
    Inventors: Vered Hornik, Michel M. Afargan, Gary Gellerman