Patents by Inventor Michel Malaise

Michel Malaise has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of early diagnosis of immune-mediated inflammatory disease
    Patent number: 11047856
    Abstract: An in-vitro method for early diagnosing or prediction of immune-mediated inflammatory diseases, comprising: —obtaining a sample from a subject; —quantifying simultaneously by one LC/MS-MS analysis of said sample, a presence of V65 vitronectin fragment or fragment, variant or degradation product thereof; and a presence of a complement C3f or fragment or variant or degradation products thereof.
    Type: Grant
    Filed: June 23, 2017
    Date of Patent: June 29, 2021
    Assignees: UNIVERSITE DE LIEGE, CENTRE HOSPITALIER UNIVERSITAIRE DE LIEGE
    Inventors: Michel Malaise, Dominique De Seny
  • TARGETS AND AGENTS FOR THE TREATMENT OF IMPAIRED BONE FRACTURE HEALING
    Publication number: 20140212380
    Abstract: The application teaches a composition comprising one or more pharmaceutical active ingredients selected from the group consisting of interleukin-8 (IL-8 or CXCL8), a functional fragment of IL-8, a functional variant of IL-8, and an agonist of IL-8 receptor, for therapeutic and/orprophylactic interventions in impaired bone fracture healing, such as but not limited to non-union fractures, mal-union fractures, or delayed union fractures.
    Type: Application
    Filed: June 11, 2012
    Publication date: July 31, 2014
    Applicants: Universite Libre De Bruxelles, Centre Hospitalier Universitaire de Liege, Universite de Liege, Bone Therapeutics SA
    Inventors: Valerie Gangji, Jean-Philippe Hauzeur, Dominique De Seny, Myrielle Mathieu, Aude Ingels, Sabrina Rigutto, Delphine Spruyt, Enrico Bastianelli, Valentina Albarani, Xavier Pesesse, Michel Malaise
  • MARKERS FOR IMPAIRED BONE FRACTURE HEALING
    Publication number: 20140100137
    Abstract: The present application discloses particularly interleukin-8 (IL-8) as a novel biomarker for the prediction, diagnosis, prognosis and/or monitoring of impaired bone fracture healing; and related methods, uses and kits.
    Type: Application
    Filed: June 11, 2012
    Publication date: April 10, 2014
    Applicants: Universite Libre De Bruxelles, Certre Hospitalier Universitaire de Liege, Universite de Liege, Bone Therapeutics SA
    Inventors: Valerie Gangji, Jean-Philippe Hauzeur, Dominique De Seny, Myrielle Mathieu, Aude Ingels, Sabrina Rigutto, Delphine Spruyt, Enrico Bastianelli, Valentina Albarari, Xavier Pesesse, Michel Malaise
  • BIOMARKERS FOR OSTEOARTHRITIS
    Publication number: 20140038841
    Abstract: The invention relates to biomarkers which may be used individually or in combination to diagnose osteoarthritis. In particular, it relates to the use of one or more of V65 vitronectin fragment or fragments, variants or degradation products thereof; complement fragment C3f or fragments, variants or degradation products thereof; or a decreased concentration of CTAPIII protein or fragments, variants or degradation products thereof, as a marker of osteoarthritis.
    Type: Application
    Filed: January 31, 2012
    Publication date: February 6, 2014
    Applicants: L'University de Liege, UNIVERSITY OF BRISTOL, CENTRE HOSPITALIER UNIVERSITAIRE LIEGOIS
    Inventors: Mohammed Sharif, Michel Malaise, Dominique De Seny