Abstract: A method and control system for determining and applying stimulation settings for a brain stimulation probe (10, 12) is provided. The brain stimulation probe (10, 12) comprises a plurality of stimulation electrodes (11). The method comprises for multiple stimulation electrodes (11) of the plurality of stimulation electrodes (11): applying a test current and determining a corresponding patient response, determining a volume of influence based (32, 52, 71, 91) on the test current and a position of the stimulation electrode (11), combining the volume of influence (32, 52, 71, 91) and the corresponding patient response with generalized anatomic knowledge of stimulation induced behavior for associating the volume of influence (32, 52, 71, 91) to an anatomic structure (33, 43, 53), and determining an intersection (41, 51) of the volume of influence (32, 52, 71, 91) and the associated anatomic structure (33, 43, 53).

Abstract: System for providing a stimulus comprising a probe with multiple electrodes each capable of providing a particular current to surrounding tissue a generator for providing to each of the electrodes the particular current a controller for controlling the generator to provide current to the electrodes to achieve a desired electrical field around the probe.

Abstract: A device (1) for transferring a pattern (12) from a stamp (10) to a substrate (20) comprises a table (22) for supporting a substrate (20), a flexible stamp (10) and a movably arranged body (25) having a pressure chamber (27) for exerting pressure on a portion of the stamp (10), so that the portion is pushed toward the substrate (20) and contacts the substrate (20). During a pattern transferring process, the body (25) is moved. As a result, adjacent portions of the stamp (10) successively go through a process of being pushed toward the substrate (20), getting in contact with the substrate (20), and being allowed to move back in place again. In this way, it is achieved that the pattern (12) of the stamp (10) is transferred to the substrate (20), without the introduction of vibrations, so that the transfer of the pattern (12) takes place in a highly accurate fashion.

Abstract: A device for cranial implantation, comprising a ferrule and a plate for placement in the ferrule is provided. Furthermore, a neurological implant system comprising a probe and a device for cranial implantation is provided.

Abstract: The invention relates to a probe (10) for an implantable medical device. The probe has a distal end (2) and a proximal end (3), and the probe (10) moreover comprises an electrode (1) at the distal end. The electrode is connected to a wire (5) extending from the electrode to the proximal end of the probe, where the resistivity of the wire is non-uniform along the length of the wire. The wire may have high resistivity at the distal end of the probe and low resistivity wires elsewhere. The high resistivity wires reduce the peak current density in the tissue of an implanted device, and thus prevents destructive heating and/or undesired stimulation of tissue during MRI examination. This highly contributes to MR safety which is a highly desired feature for these implantable electrical stimulation devices.

Abstract: The invention relates to an implantable connection device (100) comprising a porous carrier (120) to which bone tissue (1) can attach and an electrical device that is embedded in the carrier or at least space for such a device. The carrier may particularly comprise ceramic particles, for example a mixture of hydroxyapatite and tricalcium phosphate. The electrical device may consist of one or more feedthrough wires to which leads (11, 21) of external devices can be coupled on both sides of the connection device. The connection device can for example be implemented into the skull (1) of a patient to provide an electrical connection between electrodes in the brain and an external pulse generator.

Abstract: The invention relates to a neurostimulation system, particularly for deep brain stimulation (DBS), comprising a spatial array (130) of stimulation electrodes (132) and an associated controller (110). The controller (110) is adapted to sequentially supply electrical pulses to different subsets of the stimulation electrodes (132). Preferably, the controller (110) comprises a single pulse-generator (112) and a multiplexing unit (111) for distributing the pulses to different stimulation electrodes. The stimulation electrodes (132) may preferably be arranged on probes (131).

Abstract: The present disclosure provides for systems and methods enabling the insertion of leads (as used e.g., in a framework of the brain treatment therapies) through a target anatomy for conforming with a target tissue region. An exemplary lead includes at least a partially curved portion for conforming with a geometry defined by the target tissue region. In an exemplary embodiment, the system relates to stimulating targets in the brain for improved post-operative steering of an applied electric field. The leads can be either pre-curved or put under transversal mechanical strain during insertion such that a certain curved curvature of the insertion trajectory is achieved. The system includes at least a first insertion tool removably engaged with respect to the lead for guiding and providing mechanical support to the lead during insertion.

Abstract: The invention relates to an electrode system (200) that is particularly suited for deep brain stimulation. According to a preferred embodiment, the electrode system (200) comprises an elongated probe body (202) carrying a plurality of annular stimulation electrodes (201) of radius r and axial extension h that are axially distributed at distances d. The axial extension h is preferably smaller than the diameter 2r and preferably larger than the distance d. Moreover, the electrode system (200) optionally comprises a plurality of microelectrodes (203) projecting radially away from the probe body (202), said microelectrodes (203) being suited for recording neurophysio logic potentials.

Abstract: A stimulation apparatus includes a stimulation lead (102), a multiplexer (114), a stimulation signal generator (116), and a signal detector (120). The stimulation lead (102) includes a plurality of stimulation electrodes (112) disposed in an array about a distal portion of the lead body (110). The arrangement of the electrodes (112) facilitates the controlled steering of stimulating electrical field (118) in three dimensions. Four dimensional field steering may also be provided.

Abstract: Dispenser (18) to accommodate electronic cards (1). The electronic cards (1) have a layer on which a predetermined image is to be provided. The dispenser (18) has an opening (24) for allowing the electronic cards (1) to be removed from the dispenser (18). The dispenser also has an imaging unit (26) to provide the image on the layer when the electronic cards (1) pass the opening (24). The dispenser may be connected to a game controlling system.

Abstract: The present invention relates to a cooling system for an electronic substrate comprising a heat transfer fluid (4, 10). The heat transfer fluid (4, 10) is arranged to flow along a path (5, 11, 12) by capillary force.

Abstract: The invention relates to a method of monitoring a person having an interest to an object. The method comprising steps of: (210) providing a data processor (111) for obtaining interaction data related to a remote interaction between the person and at least one of a plurality of the objects (131, 132, 133), (240) using the data processor for analysis of the interaction data to identify a particular one of the objects (133), to which the person has the interest, and (250) obtaining additional data related to the particular object for informing the person about the particular object. The analysis of the interaction data may comprise a step (220) of identifying a remote location where the interest of the person is focused, and a step (230) of determining locations of the objects with respect to the remote location.

Abstract: A playing piece (10, 20) for use in a board game, and comprising at least one shapeable segment (11, 21), an input (12) and shaping means (13). An input signal from an outside control unit (17) is received at the input (12), the input signal representing a particular shape and/or size of the playing piece (10, 20). The shaping means (13) couples the input (12) to the shapeable segment (11, 21) to deform the shapeable segment (11, 21) in dependence of the input signal, for obtaining the particular shape and/or size of the playing piece (10, 20).

Abstract: A device (1) for transferring a pattern (12) from a stamp (10) to a substrate (20) comprises a table (22) for supporting a substrate (20), a flexible stamp (10) and a movably arranged body (25) having a pressure chamber (27) for exerting pressure on a portion of the stamp (10), so that the portion is pushed toward the substrate (20) and contacts the substrate (20). During a pattern transferring process, the body (25) is moved. As a result, adjacent portions of the stamp (10) successively go through a process of being pushed toward the substrate (20), getting in contact with the substrate (20), and being allowed to move back in place again. In this way, it is achieved that the pattern (12) of the stamp (10) is transferred to the substrate (20), without the introduction of vibrations, so that the transfer of the pattern (12) takes place in a highly accurate fashion.

Abstract: The present invention relates to an elongated display fiber (1) comprising an optical fiber body (2) having a plurality of pixel positions distributed along the length of said fiber (1). At least one light source (3) is arranged to selectively illuminate said fiber (1) from at least one end thereof. Addressing means are operably associated with said fiber for sequential addressing of one of each of said pixel positions. The display fiber (1) further comprises means for selectively causing said fiber (1) to emit light at said addressed one of said pixel positions. The present invention further relates to a display apparatus (11) comprising at least one elongated display fiber (1) according to the present invention.

Abstract: A pawn (10) for use on a board (21) is provided. The pawn (10) is arranged to provide a trigger signal upon a touch of a triggerable part of the pawn (10) by a user, and comprises communication means for communicating the trigger signal to a board (21). The pawn (10) comprises at least two separate triggerable sub-parts (11, 12) for, upon a touch of each respective one of the at least two separate triggerable sub-parts (11, 12) by a user, respectively providing a first and a second trigger signal. The first and the second trigger signal are mutually distinguishable. Such a pawn (10) can easily be used for activating a certain function of a set of functions. A function is selected by touching a corresponding triggerable sub-part (11, 12).

Abstract: A system for manipulation of a body of fluid, in particular a fluid droplet comprises several control electrodes to which an adjustable voltage is applied to control displacement of the droplet on the basis of the electrowetting effect. There is a counter electrode having a fixed voltage between the body of fluid and one of the control electrodes. Further, as the counter electrode and the control electrodes are located at the same side of the fluid droplet, the fluid droplet is freely accessible at its side remote from the counter electrode and the control electrodes. Hence, the fluid droplet can be employed as an object carrier and a pay-load can be placed on the droplet from the freely accessible side.

Abstract: The invention relates to a method for transferring a pattern from a stamping surface (31) of a stamp (30) to a receiving surface (21) of a substrate (20). The pattern is transferred to the receiving surface (21) by successively bringing portions of the pattern within such a range of the receiving surface (21) during a certain period, that the pattern is locally transferred from the stamping surface (31) to the receiving surface (21). The individual portions can be moved by means of individual actuators (50). By applying the method, the transfer of the pattern can be performed according to a wave, which is for example ring-shaped, moving from the center of the receiving surface (21) to the circumference, or linear, moving from side of the receiving surface (21) to an opposite side.

Abstract: A vertical interconnect (15) in an electronic device (10) is manufactured non-photolithographically. This is done by modifying a surface (20,30) of either a metal layer (3) or an intermediate layer of an electrically insulating material (21), and subsequently depositing a composition with a first and a second polymer. Phase separation of the two polymers will lead to a first (6) and a second sub-layer (7), of which the first sub-layer (6) is removed. An upper layer (9) of electrically conducting material can be deposited then or after a further etching step. This results in the vertical interconnect (15).