Abstract: The compounds are nucleoside and nucleotide analogues that can be used as anticancer or antiviral agents.

Abstract: The present invention relates to an ultrasound imaging system (10) for inspecting an object (33) in a volume (32). The ultrasound imaging system comprises an ultrasound image acquisition probe (14) for acquiring three-dimensional ultrasound images and providing three-dimensional ultrasound image data, comprising a tracking device (25, 27) for tracking a position of the ultrasound image acquisition probe (14) and providing a viewpoint position (128, 130) of the three-dimensional ultrasound images. By this, an improved initialization and improved co-registration and co-segmentation is enabled by providing a plurality of three-dimensional ultrasound images and their respective viewpoint positions (128, 130), and to conduct a segmentation (80) of the object (33) simultaneously out of the plurality of three-dimensional ultrasound images and taking into account the viewpoint positions (128, 130).

Abstract: Nucleoside analogues that can be used as anticancer or antiviral agents are presented. These compounds are nucleoside and/or nucleotide prodrugs. In particular, the subject matter relates to nucleoside analogues comprising a tetrahydrofuranyl, or tetrahydrothienyl moiety which: have a quaternary stereogenic all-carbon center at the 3? position and bear a phosphoryl group at either one of, or both of positions C5? and/or C3?; have a quaternary stereogenic all-carbon center at one of the 3? position, 2? position, or no quaternary stereogenic center at all, and bear a ?-blocked lipoate derivative attached through an amide bond to the primary amine of the nucleobase; or have a quaternary stereogenic all-carbon center at the 2? position and bear a phosphorylated prodrug at the C5?-position and a ?-blocked lipoate derivative attached through an amide bond to the primary amine of the nucleobase.

Abstract: The present invention relates to an ultrasound imaging system (10) for inspecting an object (97) in a volume (40). The ultrasound imaging system comprises an image processor (36) configured to conduct a segmentation (80) of the object (97) simultaneously out of three-dimensional ultrasound mage data (62) and contrast-enhanced three-dimensional ultrasound image data (60). In particular, this may be done by minimizing an energy term taking into account both the normal three-dimensional ultrasound image data and the contrast-enhanced three-dimensional image data. By this, the normal three-dimensional ultrasound image data and the contrast-enhanced three-dimensional image data may even be registered during segmentation. Hence, this invention allows a more precise quantification of one organ in two different modalities as well as the registration of two images for simultaneous visualization.

Abstract: The present invention relates to an ultrasound imaging system (10) for inspecting an object (97) in a volume (40). The ultrasound imaging system comprises an image processor (36) configured to conduct a segmentation (80) of the object (97) simultaneously out of three-dimensional ultrasound mage data (62) and contrast-enhanced three-dimensional ultrasound image data (60). In particular, this may be done by minimizing an energy term taking into account both the normal three-dimensional ultrasound image data and the contrast-enhanced three-dimensional image data. By this, the normal three-dimensional ultrasound image data and the contrast-enhanced three-dimensional image data may even be registered during segmentation. Hence, this invention allows a more precise quantification of one organ in two different modalities as well as the registration of two images for simultaneous visualization.

Abstract: The present invention relates to an ultrasound imaging system (10) for inspecting an object (97) in a volume (40). The ultrasound imaging system comprises an image processor (36) configured to conduct a segmentation (80) of the object (97) simultaneously out of three-dimensional ultrasound mage data (62) and contrast-enhanced three-dimensional ultrasound image data (60). In particular, this may be done by minimizing an energy tem taking into account both the normal three-dimensional ultrasound image data and the contrast-enhanced three-dimensional image data. By this, the normal three-dimensional ultrasound image data and the contrast-enhanced three-dimensional image data may even be registered during segmentation. Hence, this invention allows a more precise quantification of one organ in two different modalities as well as the registration of two images for simultaneous visualization.

Abstract: The present invention relates to an ultrasound imaging system (10) for inspecting an object (33) in a volume (32). The ultra-sound imaging system comprises an ultrasound image acquisition probe (14) for acquiring three-dimensional ultrasound images and providing three-dimensional ultrasound image data, comprising a tracking device (25, 27) for tracking a position of the ultrasound image acquisition probe (14) and providing a viewpoint position (128, 130) of the three-dimensional ultrasound images. By this, an improved initialization and improved co-registration and co-segmentation is enabled by providing a plurality of three-dimensional ultrasound images and their respective viewpoint positions (128, 130), and to conduct a segmentation (80) of the object (33) simultaneously out of the plurality of three-dimensional ultrasound images and taking into account the viewpoint positions (128, 130).

Abstract: The present invention relates to an ultrasound imaging system (10) for inspecting an object (97) in a volume (40). The ultrasound imaging system comprises an image processor (36) configured to conduct a segmentation (80) of the object (97) simultaneously out of three-dimensional ultrasound mage data (62) and contrast-enhanced three-dimensional ultrasound image data (60). In particular, this may be done by minimizing an energy tem taking into account both the normal three-dimensional ultrasound image data and the contrast-enhanced three-dimensional image data. By this, the normal three-dimensional ultrasound image data and the contrast-enhanced three-dimensional image data may even be registered during segmentation. Hence, this invention allows a more precise quantification of one organ in two different modalities as well as the registration of two images for simultaneous visualization.

Abstract: A method may include receiving, via a first network, a message identifying an event, where the event is associated with an entity, and the event is destined for at least one user. The method may include determining, by a processor of a computing device, a type of the event, and accessing, by the processor, a user profile associated with a first user of the at least one user, where the user profile associates the first user with the entity. The method may include determining, by the processor, a communication channel for delivering information associated with the event to the first user, where the user profile includes an association between the communication channel and the type of the event. The method may include forwarding, via a second network, to the first user, the information associated with the event, where the information associated with the event is forwarded via the communication channel.

Abstract: The present disclosure describes, among other things, a method. The method may include receiving, by a computing device, a first request for a workflow from an external system. The method may include determining, by the computing device, a priority level associated with the workflow. The method may include determining, by the computing device, a queue in a priority stack, wherein the queue is associated with the priority level. The method may include adding, by the computing device, the first request for the workflow to the queue.

Abstract: The present disclosure describes, among other things, a method. The method may include receiving a communication from a user through a first communication channel. The method may include matching the communication with a workflow based on a correlation between the workflow and an indicia associated with the first communication channel and the user. The method may include processing the communication according to a first step in the workflow.

Abstract: An absorption refrigeration system which utilizes absorption with a double separating effect where the pressure of the condenser (K2) is offset relative to the pressure of the second generator (G2). In this system, absorption of the working mixture is achieved using methanol as the refrigerating agent and a compound having a methylphenol group as a solvent. The system is useful for producing cold or heat, particularly for the air conditioning of elementary units of a building.

Abstract: The component-connecting device comprises several stacked and assembled wafers. Each wafer is made of an insulating material and includes conductive tracks that are rectilinear and parallel to one another. The tracks of two adjacent wafers are perpendicular. The tracks of the different wafers are made on a given side of the device. The device has zones for the connection of a component to that face, of the faces bearing the tracks, which is free, and these zones are electrically connected to tracks of other wafers. Finally, the tracks of the different wafers are extended as a connection zone with the exterior.

Abstract: An integrated circuit for convolution type computations of the form ##EQU1## where j-i+k, and j and k are integers and i is a natural integer, C.sub.i being complex coefficients and X.sub.j being complex or real input data, for use in digital signal processing. A plurality of cells are connected in a sequence, all receiving simultaneously the input data; the complex coefficients are subsequently sent on a propagation bus to a cell first in the sequence of connected cells. Each cell includes a multiplier, and an adder accumulator, and a transfer circuit for transferring received coefficients to the next cell. In each cell, sequentially received coefficients are first used for computation and then transferred by the transfer circuit with a suitable delay. A logic device controls the time distribution and repetition of the real and imaginary parts of the input data.

Abstract: An object of the invention is a device for interconnection between an integrated circuit and an electrical circuit, such as a printed circuit. This device has, depending on the desired interconnection, an insulating platelet or several, stacked insulating platelets. Each of the platelets is crossed by a pre-determined number of electricity conducting channels without offset and by a pre-determined, non-zero number of electricity conducting channels with an offset in the plane of the platelet and in a direction that is prefixed and proper to the platelet. Selected conduction routes are established by burning out the non-selected channels. The device is placed between the active face of the integrated circuit and the electrical circuit.

Abstract: The invention pertains mainly to a reconfigurable computing device. The main object of the invention is a computer comprising redundant elements. The computer according to the present invention can function when there is a failure of one of the elements that constitute it. In this case, the redundant element takes the place of the malfunctioning element. Should the computer according to the present invention be in a critical stage, i.e. a situation where any interruption in computation would have serious consequences, the reconfiguring of the system is postponed to a later instant corresponding to the end of the critical stage. The invention applies mainly to the performing of digital computations.

Abstract: A sampling circuit connected directly to the distillation column consists of a primary loop formed by a sampling tube which penetrates into the column in a region of expansion and vaporization and is equipped with means for limiting the velocity of the vapor collected therein and for separating the entrained liquid fraction if necessary. The sampling circuit further comprises a condenser and a filter, the condensate being returned to the column by a circulating pump and a withdrawal of condensate being effected by a secondary loop for supplying an analyzing device in parallel.