Abstract: The invention relates to a device for freeze-drying a liquid-containing composition, including but not limited to injectable compositions, in particular pharmaceutical compositions, biological compositions, cosmetic compositions or medical nutritional products. In particular, the present disclosure relates to a device suitable for freeze-drying liquid-containing compositions in a continuous process and to methods therefore. The device for freeze-drying a liquid containing composition in a continuous process comprises one or more, preferably three or more, of a spinner, a transportation mechanism, a vial handler, a vacuum door, and a stoppering system.