Patents by Inventor Michel R. Franz

Michel R. Franz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sustained release, bilayer buoyant dosage form
    Patent number: 5232704
    Abstract: Disclosed is a sustained release pharmaceutical dosage form including a drug and adapted to release the drug over an extended period of time. The dosage form comprises a capsule including a non-compressed bi-layer formulation; one layer comprising a drug release layer and the other a buoyant or floating layer, the pharmaceutical dosage form providing extended gastric residence time of the bi-layer formulation so that substantially all of the drug is released in the stomach over an extended period. The dosage form has a large diameter in relation to its size and an initial density of less than 1. The floating layer of the described pharmaceutical dosage form is formulated to provide buoyancy to the dosage form and diametral increase, the floating layer including a polymer which has the properties of a gelling agent and which upon contact with gastric fluid hydrates and forms a gelatinous barrier. The pharmaceutical dosage form is buoyant in gastric fluid for a period up to about 13 hours.
    Type: Grant
    Filed: December 19, 1990
    Date of Patent: August 3, 1993
    Assignee: G. D. Searle & Co.
    Inventors: Michel R. Franz, Marianne P. Oth
  • Derivatives of 2-aminoacetic acid
    Patent number: 4562205
    Abstract: 2-Pentanoylaminoacetic acid and pharmaceutically suitable salts thereof are claimed for use as pharmaceuticals.The compounds are useful in producing an effect on the central nervous system, especially in the treatment of various forms of epilepsy, of disninesiae, of parkinsonism, of memory troubles, of psychic troubles and of cerebral anoxia.
    Type: Grant
    Filed: June 25, 1984
    Date of Patent: December 31, 1985
    Assignee: Continental Pharma Inc.
    Inventors: Robert G. Cavalier, Alexis A. Cordi, Claude L. Gillet, Philippe M. Janssens de Varebeke, Paul J. Niebes, Joseph L. Roba, William R. Van Dorsser, Georges E. Lambelin, Michel R. Franz
  • Method for the preparation of p-butoxyphenylacetyl-hydroxamic acid in the finely divided state and a composition containing this acid
    Patent number: 4534911
    Abstract: Method for the preparation of micronized p-butoxyphenylacetylhydroxamic acid, comprising dissolving the p-butoxyphenylacetylhydroxamic acid in a basic solution of salifying agent and then precipitating it in an acid solution in the presence of a surface-active agent.
    Type: Grant
    Filed: December 7, 1983
    Date of Patent: August 13, 1985
    Assignee: Continental Pharma, Inc.
    Inventors: Michel R. Franz, Andreas B. Vincze, Georges E. Lambelin, Alain V. Polat
  • Pharmaceutical composition and therapeutical method for treating degenerative affections of the articular cartilage
    Patent number: 4268517
    Abstract: A pharmaceutical composition for treating degenerative diseases of the articular cartilage, in particular osteoarthritis and chondromalacia, and of the degenerative processes of the articular cartilage resulting from other diseases, such as rheumatoid arthritis, this composition containing (+) - catechin and/or one of the salts thereof as an active products, said composition being administered orally, rectally, intra-articularly, intravenously or topically.
    Type: Grant
    Filed: August 30, 1979
    Date of Patent: May 19, 1981
    Assignee: Continental Pharma
    Inventors: Paul J. Niebes, Andras B. Vincze, Joseph L. Roba, Georges E. Lambelin, Daniel M. Matagne, Etienne T. Hanon, Michel R. Franz