Patents by Inventor Michel Salzet

Michel Salzet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230207300
    Abstract: A system and method for analyzing volatile organic compounds (VOCs) adsorbed on an adsorbent membrane, by low-temperature plasma and mass spectrometry (LTP-MS). The system includes a receptacle for receiving the adsorbent membrane, a low-temperature plasma ionizer configured to emit a plasma stream in a plasma emission direction, thereby ionizing the VOCs adsorbed by the membrane and forming a VOC-laden ionized gas, and a mass spectrometer for analyzing the ionized VOCs.
    Type: Application
    Filed: May 20, 2021
    Publication date: June 29, 2023
    Applicants: UNIVERSITE DE LILLE, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE HOSPITALIER REGIONAL ET UNIVERSITAIRE DE LILLE (CHRU)
    Inventors: Isabelle SALZET, Julien FRANCK, Michel SALZET, Flore HERVE
  • Patent number: 10254275
    Abstract: The invention relates to a biological material molecular analysis device characterized in that it includes:—a laser (34) optionally using an optical parametric oscillator (OPO), configured to emit a wavelength between 2.5 ym and 12 put, said configured laser (34) being intended to ablate said biological material by ejecting charged and/or uncharged particles;—a mass spectrometer (31); and—a probe (S, 10) comprising at least one first analysis fiber (A, 14), connected to the laser (34), and a transfer tube (T, 21), connected to the mass spectrometer (31).
    Type: Grant
    Filed: September 22, 2015
    Date of Patent: April 9, 2019
    Assignees: UNIVERSITE DE SCIENCES ET TECHNOLOGIES DE LILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Michel Salzet, Isabelle Fournier, Cristian Focsa, Michael Ziskind, Benoit Fatou, Maxence Wisztorski
  • Publication number: 20170285012
    Abstract: The invention relates to a biological material molecular analysis device characterized in that it includes:—a laser (34) optionally using an optical parametric oscillator (OPO), configured to emit a wavelength between 2.5 ym and 12 put, said configured laser (34) being intended to ablate said biological material by ejecting charged and/or uncharged particles;—a mass spectrometer (31); and—a probe (S, 10) comprising at least one first analysis fiber (A, 14), connected to the laser (34), and a transfer tube (T, 21), connected to the mass spectrometer (31).
    Type: Application
    Filed: September 22, 2015
    Publication date: October 5, 2017
    Inventors: Michel SALZET, Isabelle FOURNIER, Cristian FOCSA, Michael ZISKIND, Benoit FATOU, Maxence WISZTORSKI
  • Patent number: 8652514
    Abstract: Novel peptides having antimicrobial activity, and compositions containing the same.
    Type: Grant
    Filed: December 13, 2010
    Date of Patent: February 18, 2014
    Assignees: Centre National de la Recherche Scientifique, Universite des Sciences et Technologies de Lille
    Inventors: Aurélle Tasiemski, Michel Salzet, Françoise Gaill
  • Publication number: 20130004564
    Abstract: The present invention relates to novel peptides having antimicrobial activity, and compositions containing the same.
    Type: Application
    Filed: December 13, 2010
    Publication date: January 3, 2013
    Applicants: UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Aurélle Tasiemski, Michel Salzet, Françoise Gaill
  • Publication number: 20120251625
    Abstract: The use of extract of leeches' saliva as anti-bacterial agent for the manufacture of different compositions, such as a pharmaceutical composition, a cosmetic composition or a cleaning product.
    Type: Application
    Filed: October 15, 2010
    Publication date: October 4, 2012
    Applicants: UNIVERSITE DE LILLE 1 SCIENCES ET TECHNOLOGIES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Aurélie Tasiemski, Michel Salzet
  • Patent number: 8221972
    Abstract: The invention concerns a method for determining at least one target molecule map in a tissue section, using at least one (A-X)n-B conjugate, wherein A is a tag molecule of known molecular weight, X is a linker that is cleaved during sample desorption/ionization, n is an integer of at least 1, and B is a binding molecule that binds specifically to said target molecule. When using MALDI mass spectrometry, said linker molecule X may be cleaved by photodissociation during sample laser irradiation if photocleavable at the wavelength of said MALDI laser. Alternatively, when using UV-MALDI, IR-MALDI, SIMS or DESI mass spectrometry, said linker molecule X may be cleaved by fragmentation during sample desorption/ionization.
    Type: Grant
    Filed: June 7, 2006
    Date of Patent: July 17, 2012
    Assignees: Centre National de la Recherche Scientifique (CNRS), Universite des Sciences et Technologies de Lille, Eurogentec S.A.
    Inventors: Rémi Lemaire, Isabelle Fournier, Michel Salzet, Michel Dechamps, Jean-Claude Edmond Tabet, Gottfried Proess, Ivo Rudloff, Marc Lemaitre
  • Patent number: 8173768
    Abstract: A method for preventing a break out of a neurodegenerative disease in an individual and for treating an individual suffering from a neurodegenerative disease comprising the administration of an effective amount of an antimicrobial and neurotrophic peptide.
    Type: Grant
    Filed: July 13, 2009
    Date of Patent: May 8, 2012
    Assignees: Centre National de la Recherche Scientifique, Universite des Sciences et Technologies de Lille
    Inventors: Aurélie Tasiemski, Michel Salzet
  • Patent number: 8148676
    Abstract: The invention concerns improved methods for studying peptides/proteins expression in a tissue section or for determining at least one compound, in particular a protein, expression map in a tissue section, using ionic MALDI matrices.
    Type: Grant
    Filed: June 7, 2006
    Date of Patent: April 3, 2012
    Assignees: Centre National de la Recherche Scientifique (CNRS), Universite des Sciences et Technologies de Lille
    Inventors: Rémi LeMaire, Isabelle Fournier, Michel Salzet, Jean-Claude Edmond Tabet
  • Publication number: 20110151451
    Abstract: The invention concerns a method for determining at least one target molecule map in a tissue section, using at east one (A-X)n-B conjugate, wherein A is a tag molecule of known molecular weight, X is a linker that is cleaved during sample desorption/ionization, n is an integer of at least 1, and B is a binding molecule that binds specifically to said target molecule. When using MALDI mass spectrometry, said linker molecule X may be cleaved by photodissociation during sample laser irradiation if photocleavable at the wavelength of said MALDI laser. Alternatively, when using UV-MALDI, IR-MALDI, SIMS or DESI mass spectrometry, said linker molecule X may be cleaved by fragmentation during sample desorption/ionization.
    Type: Application
    Filed: June 7, 2006
    Publication date: June 23, 2011
    Inventors: Remi Lemaire, Isabelle Fournier, Michel Salzet, Michel Deschamps, Jean-Claude Edmond Tabet, Gottfried Proess, Ivo Rudloff, Marc Lemaitre
  • Publication number: 20110009329
    Abstract: A method for preventing a break out of a neurodegenerative disease in an individual and for treating an individual suffering from a neurodegenerative disease comprising the administration of an effective amount of an antimicrobial and neurotrophic peptide
    Type: Application
    Filed: July 13, 2009
    Publication date: January 13, 2011
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Aurélie TASIEMSKI, Michel SALZET
  • Publication number: 20090197295
    Abstract: The present invention relates to masks for use in mass spectrometry, in particular MALDI, tissue section analysis, comprising a plate made of or coated by an opaque material and having a thickness of less than 150 ?m, said plate comprising regularly spaced openings, wherein in the plate upper plane, the diameter D of the largest circle comprising only one opening is superior to the diameter d of a mass spectrometer, in particular a MALDI analyzer, laser beam divided by sin ?, wherein ? is the mass spectrometer, in particular a MALDI analyzer, laser beam incidence angle with respect to the sample plane. The invention also concerns processes of manufacture of the masks according to the invention, the use thereof for mass spectrometry, in particular MALDI, imaging of tissue sections, and a method for MALDI imaging of a tissue section using said masks.
    Type: Application
    Filed: May 2, 2007
    Publication date: August 6, 2009
    Inventors: Isabelle Fournier, Vincent Thomy, Michel Salzet, Maxence Wisztorski, Nicolas Verplanck
  • Publication number: 20080203289
    Abstract: The invention concerns improved methods for studying peptides/proteins expression in a tissue section or for determining at least one compound, in particular a protein, expression map in a tissue section, using ionic MALDI matrices.
    Type: Application
    Filed: June 7, 2006
    Publication date: August 28, 2008
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE
    Inventors: Remi Lemaire, Isabelle Fournier, Michel Salzet, Jean-Claude Edmond Tabet