Abstract: A system and method are described for carrying out machine learning-based automated laundry machine error/degraded status detection and maintenance by use of acoustic sensor data rendered by the laundry machines and applied to a plurality of machine learning models for use with acoustic data rendered by the laundry machines.

Abstract: A system and method are described for carrying out machine learning-based automated laundry machine error/degraded status detection and maintenance by use of acoustic sensor data rendered by the laundry machines and applied to a plurality of machine learning models for use with acoustic data rendered by the laundry machines.

Abstract: A system and method are described for carrying out machine learning-based automated laundry machine error/degraded status detection and maintenance by use of acoustic sensor data rendered by the laundry machines and applied to a plurality of machine learning models for use with acoustic data rendered by the laundry machines.

Abstract: The present invention provides MMC prodrug compounds and liposomal MMC prodrugs and compositions thereof for the treatment of cancer. The compositions include liposomes containing a phosphatidylcholine lipid, a sterol, a PEG-lipid and a MMC prodrug. The present invention also provides liposomal compositions for the treatment of cancer comprising administering to a patient in need thereof a liposome, wherein the liposome comprises: a phosphatidylcholine lipid; a sterol; a PEG-lipid and a MMC prodrug or a pharmaceutically-acceptable salt thereof.

Abstract: A size-adjustable wearable device stores and protects items, such as rings, for example. The wearable device can be designed to securely hold items, including valuables, such as rings, in a manner that allows for peace of mind and convenience while the wearer goes about a variety of different activities. The wearer can expose a storage chamber in the device by opening a cover on the underside of a band. The ring, jewelry, or other valuable can be deposited inside the storage chamber, and the cover can be placed securely over the top of the storage chamber. The wearer can then strap the band on their person. The band can be worn with the cover disposed securely and tightly against the person, thus providing an additional level of security. In some embodiments, the storage chamber can include arms to further help secure an item, such as a ring, there within.

Abstract: The present invention provides compound conjugates of matrix metalloprotease inhibitors and linked metal chelators which are useful for imaging solid tumors and treating and diagnosing certain types of diseases such as cancer.

Abstract: A pneumatic distribution device includes at least one electromagnetic pilot valve and a distribution body. The device includes at least one heat sink having a thermal conductivity of at least 0.5 W/m K, tested in accordance with the ASTM D5470 standard. The heat sink is positioned between the at least one electromagnetic pilot valve and the distribution body.

Abstract: This invention is directed generally to hydroxamic acid and amide compounds (including salts of such compounds), and, more particularly, to aryl- and heteroaryl-arylsulfonylmethyl hydroxamic acids and amides that, inter alia, inhibit protease activity, particularly matrix metalloproteinase (also known as “matrix metalloprotease” or “MMP”) activity and/or aggrecanase activity. These compounds generally correspond in structure to Formula I: wherein A1, A2, A3, E1, E2, E3, and E4 are as defined in this patent. This invention also is directed to compositions of such compounds, intermediates for the syntheses of such compounds, methods for making such compounds, and methods for treating conditions associated with MMP activity and/or aggrecanase activity, particularly pathological conditions.

Abstract: Apparatus for transferring poultry carcasses from a first overhead conveyor to a second overhead conveyor, including a transfer wheel rotatable about a shaft and disposed between the first and the second overhead conveyors. The apparatus also includes a receipt point and a discharge point, the receipt point being disposed between the first overhead conveyor and the transfer wheel, the discharge point being disposed between the transfer wheel and the second overhead conveyor, and the receipt and discharge points are disposed on a centerline of the transfer wheel. The apparatus further includes a plurality of holders, each holder being configured to receive one of the carcasses from the first overhead conveyor at the receipt point and to discharge the carcass to the second overhead conveyor at the discharge point. Each holder has a first orientation at the receipt point and a second orientation at the discharge point, and the first and second orientations are relative to the centerline and are the same.

Abstract: This invention is directed generally to proteinase (also known as “protease”) inhibitors, and, more particularly, to piperidinyl- and piperazinyl-sulfonylmethyl hydroxamic acids that, inter alia, inhibit matrix metalloproteinase (also known as “matrix metalloprotease” or “MMP”) activity and/or aggrecanase activity. Such hydroxamic acids generally correspond in structure to the following formula: (wherein A1, A2, Y, E1, E2, E3, and Rx are as defined in this specification), and further include salts of such compounds. This invention also is directed to compositions of such hydroxamic acids, intermediates for the syntheses of such hydroxamic acids, methods for making such hydroxamic acids, and methods for treating conditions (particularly pathological conditions) associated with MMP activity and/or aggrecanase activity.

Abstract: Peptide analogs of neurotensin are disclosed which are resistant to enzymatic degradation and which retain high binding affinity for neurotensin receptors. Pharmaceutical compositions of these compounds are useful for diagnostic and therapeutic purposes.

Abstract: This invention is directed generally to proteinase (also known as “protease”) inhibitors, and, more particularly, to piperidinyl- and piperazinyl-sulfonylmethyl hydroxamic acids that, inter alia, inhibit matrix metalloproteinase (also known as “matrix metalloprotease” or “MMP”) activity and/or aggrecanase activity. Such hydroxamic acids generally correspond in structure to the following formula: (wherein A1, A2, Y, E1, E2, E3, and Rx are as defined in this specification), and further include salts of such compounds. This invention also is directed to compositions of such hydroxamic acids, intermediates for the syntheses of such hydroxamic acids, methods for making such hydroxamic acids, and methods for treating conditions (particularly pathological conditions) associated with MMP activity and/or aggrecanase activity.

Abstract: The invention concerns a device wherein the coil tube (12) forming the condenser of a first heat pump assembly and the coil (13) which forms a second assembly are each fixed on vertical grids (28, 29). Said grids are arranged parallel to each other and are embedded in the concrete block (3) which forms one of the energy storage units incorporated in the system. The grids consist of concrete iron bars welded together into a network with square and rectangular meshes. The means fixing the tubes at certain intersetions of the grid are clamps of a particular type. The grids, the tubes and the clamps are embedded in the concrete block (3).

Abstract: Apparatus for transferring poultry carcasses from a first overhead conveyor to a second overhead conveyor, in which overhead conveyors the carcasses are transported suspended from shackles and the like, comprising a transfer wheel rotatable about a vertical axis and positioned between both overhead conveyors, which wheel is provided with holders for the carcasses and with first means for transferring the carcasses from the first overhead conveyor to the transfer wheel and with second means for transferring the carcasses from the transfer wheel to the second overhead conveyor, orientation means further being present for equalizing the spacial initial orientation of the carcass in the holder at receipt on the transfer wheel and the spacial final orientation of the carcass in the holder at its discharge from the transfer wheel.

Abstract: Apparatus for transferring poultry carcasses from a first overhead conveyor to a second overhead conveyor, in which overhead conveyors the carcasses are transported suspended from shackles and the like, comprising a transfer wheel rotatable about a vertical axis and positioned between both overhead conveyors, which wheel is provided with holders for the carcasses and with first means for transferring the carcasses from the first overhead conveyor to the transfer wheel and with second means for transferring the carcasses from the transfer wheel to the second overhead conveyor, orientation means further being present for equalizing the spacial initial orientation of the carcass in the holder at receipt on the transfer wheel and the spacial final orientation of the carcass in the holder at its discharge from the transfer wheel.

Abstract: A device for measuring fractions of a liquid sample comprises a casing having a vertical axis and containing a central chamber and transparent cells distributed around the chamber and permanently vented to atmosphere. Each cell is connected to the chamber by a closure cup. A capillary constriction separates each pocket from the corresponding cell. The device may be used for the preparation of antibiograms.

Abstract: A device for measuring and dispensing fractions of a liquid sample comprises a casing having a vertical axis and containing a central chamber and transparent cells distributed around the chamber. Each cell is connected to the chamber by a closure cup. A capillary constriction separates each pocket from the corresponding cell. The device may be used for the preparation of antibiograms.