Patents by Inventor Michel Simon
Michel Simon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230085651Abstract: The present invention relates to sugar-derived catanionic surfactant vesicles comprising anti-inflammatory dendrimers and to their use as a medicament, more particularly in the treatment of psoriasis.Type: ApplicationFiled: December 22, 2020Publication date: March 23, 2023Inventors: Muriel BLANZAT, Ranime JEBBAWI, Rémy POUPOT, Cédric-Olivier TURRIN, Michel SIMON, Emily CLEMENT, Hélène LABIE, Abdelouahd OUKHRIB
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Patent number: 9790111Abstract: Disclosed is a method for thickening or dehydrating sludge, which includes at least: a) a step of adding flocculants to the sludge to be treated; b) a step of flocculation by agitation of the sludge with the flocculants thus added in order to form a mixture of flocks and an aqueous solution; c) a step of mechanical separation of the flocks and the aqueous solution formed during the preceding step; d) a step of recovering the aqueous solution and the flocks that make up a treated sludge; wherein: the added flocculants are made up of at least one cationic starch (S) and at least one cationic polyacrylamide (P); the cationic starch or starches (S) including a fixed weight percentage of nitrogen of at least 2%; and the weight ratio (R) ws/(ws+wp), expressed as solids, is included between 0.6 and 0.99.Type: GrantFiled: November 28, 2013Date of Patent: October 17, 2017Assignee: Roquette FreresInventors: Laura Crowther-Alwyn, Medhi Carre, Michel Simon
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Patent number: 9566222Abstract: The present invention relates to the activation of peptidyl arginine deiminase (PADs) 1 and/or 3 in the epidermis by at least one active agent used alone or in combination, namely caffeine, acefylline and/or theobromine in a cosmetic and/or pharmaceutical composition. The present invention also relates to the use of the aforementioned active agents in cosmetics and/or therapeutics, alone or in combination, in order to improve the barrier functions of the epidermis, to prevent and/or treat symptoms related to dry skin or to improve and/or promote hydration of the keratinous layer. Finally, the invention relates to increasing the activity of PAD1 and/or PAD3 in the epidermis.Type: GrantFiled: April 11, 2012Date of Patent: February 14, 2017Assignee: PIERRE FABRE DERMO-COSMETIQUEInventors: Hélène Duplan, Sylvie Daunes-Marion, Stéphane Poigny, Marie-Claire Mechin, Guy Serre, Michel Simon
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Publication number: 20150315056Abstract: Disclosed is a method for thickening or dehydrating sludge, which includes at least: a) a step of adding flocculants to the sludge to be treated; b) a step of flocculation by agitation of the sludge with the flocculants thus added in order to form a mixture of flocks and an aqueous solution; c) a step of mechanical separation of the flocks and the aqueous solution formed during the preceding step; d) a step of recovering the aqueous solution and the flocks that make up a treated sludge; wherein: the added flocculants are made up of at least one cationic starch (A) and at least one cationic polyacrylamide (P); the cationic starch or starches (A) including a fixed weight percentage of nitrogen of at least 2%; and the weight ratio (R) mA/(mA+mP), expressed as solids, is included between 0.6 and 0.99.Type: ApplicationFiled: November 28, 2013Publication date: November 5, 2015Inventors: Laura CROWTHER-ALWYN, Medhi CARRE, Michel SIMON
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Publication number: 20140030200Abstract: The present invention relates to the activation of peptidyl arginine deiminase (PADs) 1 and/or 3 in the epidermis by at least one active agent used alone or in combination, namely caffeine, acefylline and/or theobromine in a cosmetic and/or pharmaceutical composition. The present invention also relates to the use of the aforementioned active agents in cosmetics and/or therapeutics, alone or in combination, in order to improve the barrier functions of the epidermis, to prevent and/or treat symptoms related to dry skin or to improve and/or promote hydration of the keratinous layer. Finally, the invention relates to increasing the activity of PAD1 and/or PAD3 in the epidermis.Type: ApplicationFiled: April 11, 2012Publication date: January 30, 2014Applicant: PIERRE FABRE DERMO-COSMETIQUEInventors: Hélène Duplan, Sylvie Daunes-Marion, Stéphane Poigny, Marie-Claire Mechin, Guy Serre, Michel Simon
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Publication number: 20140001361Abstract: A method is described for producing a micro-gripper, which comprises a base body and a gripping body connected integrally to the base body, which projects beyond the base body and provides a receptacle slot on a free end area in such a way that a micrometer-scale or sub-micrometer-scale object may be clamped in the receptacle slot for gripping and holding, as well as a micro-gripper according to the species.Type: ApplicationFiled: August 30, 2013Publication date: January 2, 2014Applicant: CARL ZEISS MICROSCOPY GMBHInventors: Christian GROSSE, Frank ALTMANN, Michel SIMON, Hilmar HOFFMEISTER, Detlef RIEMER
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Publication number: 20070231314Abstract: The present invention relates to a cosmetic or pharmaceutical composition comprising, in a physiologically acceptable medium, a purified natural or synthetic epidermis-specific polypeptide which is involved in horny layer cell cohesion. The invention also relates to a cosmetic or pharmaceutical composition comprising a mixture of polypeptides derived from the proteolysis of the purified polypeptide of the present invention. The present invention further relates to a method for strengthening horny layer cell cohesion which comprises applying the cosmetic or pharmaceutical composition of the present invention to the skin. Finally, the present invention relates to a method for reducing horny layer cell cohesion, and thereby promoting exfoliation, wherein said method comprises applying to the skin a cosmetic or pharmaceutical composition comprising an effective amount of at least one protease active on the polypeptide of the present invention.Type: ApplicationFiled: October 11, 2006Publication date: October 4, 2007Applicant: L'OrealInventors: Guy Bruno Serre, Michel Simon, Marina Weber-Vivat
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Publication number: 20050112150Abstract: The present invention relates to a cosmetic or pharmaceutical composition comprising, in a physiologically acceptable medium, a purified natural or synthetic epidermis-specific polypeptide which is involved in horny layer cell cohesion. The invention also relates to a cosmetic or pharmaceutical composition comprising a mixture of polypeptides derived from the proteolysis of the purified polypeptide of the present invention. The present invention further relates to a method for strengthening horny layer cell cohesion which comprises applying the cosmetic or pharmaceutical composition of the present invention to the skin. Finally, the present invention relates to a method for reducing horny layer cell cohesion, and thereby promoting exfoliation, wherein said method comprises applying to the skin a cosmetic or pharmaceutical composition comprising an effective amount of at least one protease active on the polypeptide of the present invention.Type: ApplicationFiled: October 3, 2003Publication date: May 26, 2005Applicant: SOCIETE L'OREAL S.A.Inventors: Guy Serre, Michel Simon, Marina Weber-Vivat
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Patent number: 6890720Abstract: The invention concerns an artificial antigen specifically identified by the anti-filaggrin autoantibodies present in the serum of patients suffering from rheumatoid polyarthritis, and consisting of one polypeptide comprising all or part of the sequence of one filaggrin unit or of a related molecule, in which an arginine radical has been substituted by a citrulline radical. The invention also concerns the use of this antigen for diagnosing rheumatoid polyarthritis.Type: GrantFiled: September 1, 1997Date of Patent: May 10, 2005Assignee: BiomerieuxInventors: Guy Serre, Elisabeth Girbal-Neuhauser, Christian Vincent, Michel Simon, Mireille Sebbag, Pascal Dalbon, Colette Jolivet-Reynaud, Michel Arnaud, Michel Jolivet
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Patent number: 6645509Abstract: The present invention relates to a cosmetic or pharmaceutical composition comprising, in a physiologically acceptable medium, a purified natural or synthetic epidermis-specific polypeptide which is involved in horny layer cell cohesion. The invention also relates to a cosmetic or pharmaceutical composition comprising a mixture of polypeptides derived from the proteolysis of the purified polypeptide of the present invention. The present invention further relates to a method for strengthening horny layer cell cohesion which comprises applying the cosmetic or pharmaceutical composition of the present invention to the skin. Finally, the present invention relates to a method for reducing horny layer cell cohesion, and thereby promoting exfoliation, wherein said method comprises applying to the skin a cosmetic or pharmaceutical composition comprising an effective amount of at least one protease active on the polypeptide of the present invention.Type: GrantFiled: December 29, 1999Date of Patent: November 11, 2003Assignee: Societe L'Oreal S.A.Inventors: Guy Bruno Rene Serre, Michel Simon, Marina Weber-Vivat
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Patent number: 6437193Abstract: An improved method for the selective vapor phase oxidation of propylene to acrolein in a recirculating solids reactor system using a bismuth molybdate multimetal oxide involving specific reactant concentrations (preferably 5 mol % to 30 mol % propylene, 0 to 20 mol % oxygen, and the remainder inert gas), particle size (1 to 300 micrometers), temperature (250 to 450° C.) and gas (1 to 15 seconds) and solids (2 to 60 seconds) residence times. Such a process leads to improved selectivity and propylene conversion.Type: GrantFiled: April 6, 2000Date of Patent: August 20, 2002Assignees: E. I. du Pont de Nemours and Company, AtofinaInventors: Rashmikant Maganlal Contractor, Mark William Andersen, Daniel Campos, Gerard Hecquet, Roland Kotwica, Charlotte Pham, Michel Simon, Mireille Stojanovic
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Patent number: 6310240Abstract: An improved method for the selective vapor phase oxidation of acrolein to acrylic acid in a recirculating solids reactor system using a particulate molybdenum vanadate multimetal oxide as oxidant involving specific reactant concentrations (preferably 5 mol % to 30 mol % propylene, 0 to 20 mol % oxygen, 0 to 70 mol % water, and the remainder inert gas), solids particle size (20 to 300 micrometers), temperature (250 to 450° C.) and gas (1 to 15 seconds) and solids (2 to 60 seconds) residence times. Such a process leads to improved selectivity, conversion and solids conversion ratio.Type: GrantFiled: December 23, 1998Date of Patent: October 30, 2001Assignees: E. I. du Pont de Nemours and Company, AtofinaInventors: Rashmikant Maganlal Contractor, Mark William Andersen, Daniel Campos, Gerard Hecquet, Charlotte Pham, Michel Simon, Mireille Stojanovic, Roland Kotwica, Jean-Pierre Schirmann
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Patent number: 6281384Abstract: An improved method for manufacturing acrylic acid by vapor phase oxidation of propylene in a single step or reaction stage using as solid phase oxidant a mixture of two particulate solids comprising a bismuth molybdate multimetal oxide (e.g., Mo12Co3.5Bi1.1Fe0.8W0.5Si1.4K0.05Ox) and a molybdenum vanadate multimetal oxide (e.g., Mo12V4.8Sr0.5W2.4Cu2.2Ox). Such a process is advantageously carried out in a recirculating solids reactor system wherein the particulate mixture of solids in an oxidized state reacts with a feed gas containing propylene in a vertical riser reactor and after separation from the acrylic acid gaseous product the particulate mixture of solids in a reduced state is regenerated by contact with an oxygen containing gas in a separate regeneration reactor before recirculation to the riser for further reaction.Type: GrantFiled: June 26, 1998Date of Patent: August 28, 2001Assignees: E. I. du Pont Nemours and Company, AtofinaInventors: Rashmikant Maganlal Contracter, Mark William Andersen, Jean B. Myers, Gerard Hecquet, Roland Kotwica, Mireille Stojanovic, Charlotte Pham, Michel Simon
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Publication number: 20010009885Abstract: Solid mixed oxides composition of formula (I):Type: ApplicationFiled: January 6, 2000Publication date: July 26, 2001Inventors: GERARD HECQUET, JEAN-PIERRE SCHIRMANN, MICHEL SIMON, CHARLOTTE PHAM
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Patent number: 6251821Abstract: A mixed oxide solid composition of the formulas (I): (a) Mo12Co4.7Bi1Ni2.6Fe3.7W0.5Sn0.5Si1K0.08Ox; (b) Mo12Co3.5Bi1.1Fe0.8W0.5Si1.4K0.05Ox; and (c) Mo12Co3.8Bi1.2Fe0.9W1.1Si1.5K0.05Ox, wherein x is the quantity of oxygen bonded to the other elements and depends on their oxidation states, is suitable for the manufacture of acrolein by oxidizing propylene. The solid composition reacts with propylene according to the redox reaction (1): solidoxidized+propylene→solidreduced+acrolein (1) To manufacture acrolein, gaseous propylene is passed over the solid composition. Redox reaction (1) is conducted at a temperature of 200 to 600° C., at a pressure of 1.01×104 to 1.01 to 106 Pa (0.1 to 10 atmospheres) and with a residence time of 0.01 second to 90 seconds, in the absence of molecular oxygen.Type: GrantFiled: December 14, 1999Date of Patent: June 26, 2001Assignee: Institut Francais du PetroleInventors: Gerard Hecquet, Jean-Pierre Schirmann, Michel Simon, Gilles Descat, Eric Etienne
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Patent number: 6080893Abstract: A mixed oxide solid composition of formula (I):Mo.sub.12 W.sub.a Bi.sub.b Fe.sub.c Co.sub.d Ni.sub.e Si.sub.f K.sub.g Sn.sub.h O.sub.x (I)where O.ltoreq.a.ltoreq.5, 0.5.ltoreq.b.ltoreq.5, 0.1.ltoreq.c.ltoreq.10, 0.5.ltoreq.d.ltoreq.10, 0.ltoreq.e.ltoreq.10, 0.ltoreq.f.ltoreq.15, 0.ltoreq.g.ltoreq.1, 0.ltoreq.h.ltoreq.2 and x is the quantity of oxygen bonded to the other elements and depends on their oxidation states, is used in the manufacture of acrolein by oxidizing propylene, the solid composition reacting with propylene according to the redox reaction (1):solid.sub.oxidized +propylene.fwdarw.solid.sub.reduced +acrolein(I)To manufacture acrolein, gaseous propylene is passed over a solid composition of formula (I), to conduct the redox reaction (1) by operating at a temperature of 200 to 600.degree. C., at a pressure of 1.01.times.10.sup.4 to 1.01 to 10.sup.6 Pa (0.1 to 10 atmospheres) and with a residence time of 0.01 second to 90 seconds, in the absence of molecular oxygen.Type: GrantFiled: February 27, 1998Date of Patent: June 27, 2000Assignee: Elf Atochem, S.A.Inventors: Gerard Hecquet, Jean-Pierre Schirmann, Michel Simon, Gilles Descat, Eric Etienne
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Patent number: 6025523Abstract: Solid mixed oxides composition of formula (I):Mo.sub.12 V.sub.a Sr.sub.b W.sub.c Cu.sub.d Si.sub.e O.sub.x(I)2.ltoreq.a.ltoreq.14, 0.1.ltoreq.B.ltoreq.6, 0.ltoreq.c.ltoreq.12, 0.ltoreq.d.ltoreq.6, 0.ltoreq.e.ltoreq.15; x is the quantity of oxygen bonded to the other elements and depends on their oxidation states, are used in the manufacture of acrylic acid by oxidation of acrolein, the said solid composition reacting with acrolein according to the redox reaction (1):SOLID.sub.oxidized +ACROLEIN.fwdarw.SOLID.sub.reduced +ACRYLIC ACID(1).To manufacture acrylic acid, a gaseous mixture of acrolein and of water vapor and, if appropriate, of an inert gas is passed over a solid composition of formula (I), to conduct the redox reaction (1) by operating at a temperature of 200 to 500.degree. C., at a pressure of 1.01.times.10.sup.4 to 1.01.times.10.sup.6 Pa (0.1 to 10 atmospheres), and with a residence time of 0.01 second to 90 seconds, in the absence of molecular oxygen.Type: GrantFiled: February 27, 1998Date of Patent: February 15, 2000Assignee: ELF Atochem S.A.Inventors: Gerard Hecquet, Jean-Pierre Schirmann, Michel Simon, Charlotte Pham
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Patent number: 5263035Abstract: The disclosure relates to an undulator, namely a device generating a transverse magnetic field polarized alternatively North-South and South-North along the path of an electron beam and enabling the direct conversion, in a free electron laser, of a part of the energy of a beam of relativistic electrons into light energy. The undulator comprises a conductor forming, along the path of the electron beam, undulations that wholly or partially induce the transverse magnetic field. To increase the light efficiency, it consists in providing for auxiliary current bypass connectors on said conductor. These auxiliary connectors enable the modulation of the transverse magnetic field as a function of the changing characteristics of the high frequency electrical field which increases during the arrival of a packet of electrons in the optical cavity of the laser owing to the energy yielded by these electrons.Type: GrantFiled: April 17, 1992Date of Patent: November 16, 1993Assignee: Thomson-CSFInventors: Hubert Leboutet, Michel Simon
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Patent number: 4962232Abstract: Catalytic process for the manufacture of acid fluoride selected from isobutyryl fluoride, methyl-2 butyryl fluoride, and pivaloyl fluoride from carbon monoxide, hydrogen fluoride, and an aliphatic hydrocarbon stream comprising principally an alkane having 3 to 4 carbon atoms, comprising the following series of stages:(a) introduction of at least one fluid chosen from carbon monoxide and the hydrocarbon stream into a reactor in the presence of a superacidic catalyst system comprising hydrogen fluoride, antimony pentafluoride, and at least one compound chosen from bromine, iodine, bromides, and iodides,(b) where appropriate, if it has not already been introduced during stage (a), introduction into the reactor of a fluid chosen from carbon monoxide and the hydrocarbon stream, under conditions that are suitable to permit the formation, principally, of a complex consisting of the alkyloxocarbonium cation and the anion SbF.sub.6.sup.Type: GrantFiled: November 13, 1987Date of Patent: October 9, 1990Assignee: Societe Chimique des Charbonnages, S.A.Inventors: Serge Delavarenne, Michel Fauconet, Michel Simon, Jean Sommer
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Patent number: 4840750Abstract: Catalytic process for the manufacture of acid fluoride from carbon monoxide, hydrogen fluoride, and an aliphatic hydrocarbon stream mainly containing at least one alkane containing 3 to 4 carbon atoms, comprising the following series of stages:(a) introduction of at least one fluid chosen from carbon monoxide and the hydrocarbon stream into a reactor in the presence of a superacidic catalyst system consisting essentially of hydrogen fluoride and antimony pentafluoride,(b) where appropriate, if it has not already been introduced during stage (a), introduction into the reactor of a fluid chosen from carbon monoxide and the hydrocarbon stream, the reactor being at a temperature not above 60.degree. C. to permit the formation, principally, of a complex consisting of the alkyloxocarbonium cation and the anion SbF.sub.6.sup.-,(c) conversion of the complex into acid fluoride,(d) separation of the acid fluoride, and(e) recovery of the superacidic catalyst system.Type: GrantFiled: November 16, 1987Date of Patent: June 20, 1989Assignee: Societe Chimique des Charbonnages S.A.Inventors: Serge Delavarenne, Michel Fauconet, Michel Simon, Jean Sommer