Patents by Inventor Michel Zoghbi

Michel Zoghbi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of pharmaceutically useful pyridine derivatives
    Patent number: 6437139
    Abstract: A process is provided for the preparation of compounds of formula I, useful in the preparation of compounds such as Omeprazole, Lansoprazole and Pantoprazole, wherein R1=H or CH3, R2=H or CH3, R3=Alkoxy (1-4C), OCH2CF3, Cyano, Hydrogen, Halogen, Acetoxy or Aryloxy, any electron withdrawing group or salts (organic or inorganic) of electron donating groups, R=Alkoxy, Hydroxy, Halogen, Activated ester, Tosylate, Mesylate, Thiol or Xanthyl, wherein the process for the preparation of compound of formula I employs a free radical reaction to functionalize the 2-position.
    Type: Grant
    Filed: June 23, 2000
    Date of Patent: August 20, 2002
    Assignee: PDi-Research Laboratories, Inc.
    Inventors: Michel Zoghbi, Liquin Chen
  • Synthesis of pharmaceutically useful pyridine derivatives
    Patent number: 6121454
    Abstract: A process is provided for the preparation of compounds of formula I, ##STR1## useful in the preparation of compounds such as Omeprazole, Lansoprazole and Pantoprazole, wherein R.sup.1 =H or CH.sub.3, R.sup.2 =H or CH.sub.3, R.sup.3 =Alkoxy (1-4C), OCH.sub.2 CF.sub.3, Cyano, Hydrogen, Halogen, Acetoxy or Aryloxy, any electron withdrawing group or salts (organic or inorganic) of electron donating groups, R=Alkoxy, Hydroxy, Halogen, Activated ester, Tosylate, Mesylate, Thiol or Xanthyl, wherein the process for the preparation of compound of formula I employs a free radical reaction to functionalize the 2-position.
    Type: Grant
    Filed: April 21, 1998
    Date of Patent: September 19, 2000
    Assignee: PDi-Research Laboratories, Inc.
    Inventors: Michel Zoghbi, Liquin Chen