Patents by Inventor Michele A. Kaminski

Michele A. Kaminski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3?,3?-N-bis-desmethyl-3?-N-cycloalkyl erythromycin derivatives as LHRH antagonists
    Patent number: 6387885
    Abstract: Disclosed are 3′,3′-N-bis-desmethyl-3′-N-cycloalkyl-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
    Type: Grant
    Filed: August 26, 1998
    Date of Patent: May 14, 2002
    Assignee: Abbott Laboratories
    Inventors: Christopher R. Dalton, Milan Bruncko, Michele A. Kaminski, Lisa M. Frey, Daryl R. Sauer, Fortuna Haviv
  • Tetrahydroisoquinoline derivatives as LHRH antagonists
    Patent number: 5981521
    Abstract: Tetrahydroisoquinoline derivatives of the formula: ##STR1## or a pharmaceutically acceptable salt, ester, or prodrug thereof, having activity as an LHRH antagonist, as well as pharmaceutical compositions containing the same, and methods for their use and preparation.
    Type: Grant
    Filed: November 13, 1998
    Date of Patent: November 9, 1999
    Assignee: Abbott Laboratories
    Inventors: Fortuna Haviv, Wesley J. Dwight, Bradley W. Crawford, Rolf E. Swenson, Milan Bruncko, Michele A. Kaminski, Lisa M. Frey, John DeMattei, Jonathan Greer
  • 3',3-N-bis-substituted macrolide LHRH antagonists
    Patent number: 5972898
    Abstract: Disclosed are 3',3'-N-bisdesmethyl-3',3'-N-bis-substituted-6-O-methyl-11-deoxy-11,12-cyc lic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: October 26, 1999
    Assignee: Abbott Laboratories
    Inventors: Daryl R. Sauer, Fortuna Haviv, John Randolph, Nicholas A. Mort, Christopher R. Dalton, Milan Bruncko, Michele A. Kaminski, Bradley W. Crawford, Lisa Marie Frey, Jonathan Greer
  • Macrolide LHRH antagonists
    Patent number: 5955440
    Abstract: Disclosed are 3'-N-desmethyl-3'-N-substituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: September 21, 1999
    Assignee: Abbott Laboratories
    Inventors: Daryl R. Sauer, Fortuna Haviv, John Randolph, Nicholas A. Mort, Christopher R. Dalton, Milan Bruncko, Michele A. Kaminski, Bradley W. Crawford, Lisa Marie Frey, Jonathan Greer
  • Process for piperidine derivatives
    Patent number: 5675009
    Abstract: The present invention is related to a novel process for preparing certain piperidine derivatives which are useful as antihistamines, antiallergy agents and bronchodilators.
    Type: Grant
    Filed: May 1, 1995
    Date of Patent: October 7, 1997
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Chi-Hsin Richard King, Michele A. Kaminski
  • Process for piperidine derivatives
    Patent number: 5663353
    Abstract: The present invention is related to a novel process for preparing certain piperidine derivatives which are useful as antihistamines, antiallergy agents and bronchodilators.
    Type: Grant
    Filed: May 2, 1995
    Date of Patent: September 2, 1997
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Chi-Hsin Richard King, Michele A. Kaminski
  • Process for piperidine derivatives
    Patent number: 5654433
    Abstract: The present invention is related to a novel process for preparing certain piperidine derivatives which are useful as antihistamines, antiallergy agents and bronchodilators.
    Type: Grant
    Filed: May 3, 1995
    Date of Patent: August 5, 1997
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Chi-Hsin Richard King, Michele A. Kaminski
  • Process for piperidine derivatives
    Patent number: 5652370
    Abstract: The present invention is related to a novel process for preparing certain piperidine derivatives which are useful as antihistamines, antiallergy agents and bronchodilators.
    Type: Grant
    Filed: May 2, 1995
    Date of Patent: July 29, 1997
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Chi-Hsin Richard King, Michele A. Kaminski
  • Process for piperidine derivatives
    Patent number: 5650516
    Abstract: The present invention is related to a novel process for preparing certain piperidine derivatives which are useful as antihistamines, antiallergy agents and bronchodilators.
    Type: Grant
    Filed: May 3, 1995
    Date of Patent: July 22, 1997
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Chi-Hsin Richard King, Michele A. Kaminski
  • Process for piperidine derivatives
    Patent number: 5644061
    Abstract: The present invention is related to a novel process for preparing certain piperidine derivatives which are useful as antihistamines, antiallergy agents and bronchodilators.
    Type: Grant
    Filed: May 1, 1995
    Date of Patent: July 1, 1997
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Chi-Hsin Richard King, Michele A. Kaminski
  • Process for piperidine derivatives
    Patent number: 5631375
    Abstract: The present invention is related to a novel process for preparing certain piperidine derivatives which are useful as antihistamines, antiallergy agents and bronchodilators, these piperidine derivatives can be described by the following formulas: ##STR1## wherein R.sub.1 represents hydrogen or hydroxy;R.sub.2 represents hydrogen; orR.sub.1 and R.sub.2 taken together form a second bond between the carbon atoms bearing R.sub.1 and R.sub.2 ;n is an integer of from 1 to 5;R.sub.3 is --CH.sub.2 OH, --COOH or --COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched;each of A is hydrogen or hydroxy; andpharmaceutically acceptable salts, hydrates and individual optical isomers thereof.
    Type: Grant
    Filed: January 6, 1995
    Date of Patent: May 20, 1997
    Assignee: Merrell Pharmaceuticals, Inc.
    Inventors: Chi-Hsin R. King, Michele A. Kaminski, Teng-Man Chen
  • Process for piperidine derivatives
    Patent number: 5618940
    Abstract: The present invention is related to a novel process for preparing certain piperidine derivatives which are useful as antihistamines, antiallergy agents and bronchodilators.
    Type: Grant
    Filed: May 2, 1995
    Date of Patent: April 8, 1997
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Chi-Hsin R. King, Michele A. Kaminski