Patents by Inventor Michele Alberto Brunori

Michele Alberto Brunori has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-neoplastic viral agents
    Patent number: 7078028
    Abstract: A viral DNA construct, and virus encoded thereby, is provided having one or more tumour specific transcription factor binding sites in place of one or more wild type transcription factor binding sites operatively positioned in the promoter region which controls expression of early genes responsible for viral nucleic acid replication. Preferred constructs place the tumour specific transcription factor binding sites in operative relation to DNA polymerase, DNA terminal protein and/or DNA binding protein. Compositions and constructs contained therein are provided, particularly for use in therapy. Methods of treating patients for neoplasms are also provided.
    Type: Grant
    Filed: September 29, 2003
    Date of Patent: July 18, 2006
    Assignee: BTG International Limited
    Inventors: Richard Iggo, Michele Alberto Brunori
  • Anti-neoplastic viral agents
    Publication number: 20040047836
    Abstract: A viral DNA construct, and virus encoded thereby, is provided having one or more tumour specific transcription factor binding sites in place of one or more wild type transcription factor binding sites operatively positioned in the promoter region which controls expression of early genes responsible for viral nucleic acid replication.
    Type: Application
    Filed: September 29, 2003
    Publication date: March 11, 2004
    Applicant: BTG International Limited
    Inventors: Richard Iggo, Michele Alberto Brunori
  • Anti-neoplastic viral agents
    Patent number: 6544507
    Abstract: A viral DNA construct, and virus encoded thereby, is provided having one or more tumor specific transcription factor binding sites in place of one or more wild type transcription factor binding sites operatively positioned in the promoter region which controls expression of early genes responsible for viral nucleic acid replication. Preferred constructs place the tumor specific transcription factor binding sites in operative relation to DNA polymerase, DNA terminal protein and/or DNA binding protein. Compositions and constructs contained therein are provided, particularly for use in therapy. Methods of treating patients for neoplasms are also provided.
    Type: Grant
    Filed: July 30, 2001
    Date of Patent: April 8, 2003
    Assignee: BTG International Limited
    Inventors: Richard Iggo, Michele Alberto Brunori
  • Anti-neoplastic viral agents
    Publication number: 20020168349
    Abstract: A viral DNA construct, and virus encoded thereby, is provided having one or more tumor specific transcription factor binding sites in place of one or more wild type transcription factor binding sites operatively positioned in the promoter region which controls expression of early genes responsible for viral nucleic acid replication.
    Type: Application
    Filed: July 30, 2001
    Publication date: November 14, 2002
    Inventors: Richard Iggo, Michele Alberto Brunori