Patents by Inventor Michele Carbone

Michele Carbone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND KITS FOR ANALYSIS OF HMGB1 ISOFORMS
    Publication number: 20200363416
    Abstract: In accordance with some embodiments herein, methods of determining signatures of HMGB1 isoforms in a subject are provided. In some embodiments, antibodies that bind specifically to HMGB1 isoforms are provided. In some embodiments, immunoassay kits are provided.
    Type: Application
    Filed: August 4, 2020
    Publication date: November 19, 2020
    Inventors: Haining Yang, Michele Carbone
  • Methods for diagnosing a predisposition to develop cancer
    Patent number: 10344333
    Abstract: Systems, methods, and computer readable media for diagnosing or characterizing a genetic predisposition to develop cancer are provided. Nucleic acids comprising a germline nucleic acid sequence encoding the BRCA1 associated protein 1 are sequenced or probed to determine if the nucleic acid sequence includes alterations that predispose a subject to develop cancer.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: July 9, 2019
    Assignees: Institute For Cancer Research, University of Hawaii
    Inventors: Joseph R. Testa, Michele Carbone, Mitchell Cheung, Jianming Pei
  • METHODS AND KITS FOR ANALYSIS OF HMGB1 ISOFORMS
    Publication number: 20180011098
    Abstract: In accordance with some embodiments herein, methods of determining signatures of HMGB1 isoforms in a subject are provided. In some embodiments, antibodies that bind specifically to HMGB1 isoforms are provided. In some embodiments, immunoassay kits are provided.
    Type: Application
    Filed: January 19, 2016
    Publication date: January 11, 2018
    Applicant: University of Hawaii
    Inventors: Haining Yang, Michele Carbone
  • Treatment and prevention of cancer with HMGB1 antagonists
    Patent number: 9561274
    Abstract: Embodiments provided herewith relate to methods and compositions for treating or preventing cancer. More particularly, several embodiments are drawn to treating or preventing malignant mesothelioma with antagonists of high-mobility group box 1 (HMGB1).
    Type: Grant
    Filed: June 7, 2012
    Date of Patent: February 7, 2017
    Assignee: UNIVERSITY OF HAWAII
    Inventors: Haining Yang, Michele Carbone, Marco E. Bianchi
  • Biomarker of asbestos exposure and mesothelioma
    Patent number: 9244074
    Abstract: Several embodiments provided herein relate to methods of diagnosing asbestos exposure or mesothelioma. Several embodiments also relate to methods of differentiating whether a tumor of the lung is lung cancer or mesothelioma.
    Type: Grant
    Filed: June 7, 2012
    Date of Patent: January 26, 2016
    Assignees: University of Hawaii, New York University
    Inventors: Haining Yang, Michele Carbone, Harvey I. Pass
  • BIOMARKER OF ASBESTOS EXPOSURE AND MESOTHELIOMA
    Publication number: 20140170685
    Abstract: Several embodiments provided herein relate to methods of diagnosing asbestos exposure or mesothelioma. Several embodiments also relate to methods of differentiating whether a tumor of the lung is lung cancer or mesothelioma.
    Type: Application
    Filed: June 7, 2012
    Publication date: June 19, 2014
    Inventors: Haining Yang, Michele Carbone, Harvey I. Pass
  • TREATMENT AND PREVENTION OF CANCER WITH HMGB1 ANTAGONISTS
    Publication number: 20140127134
    Abstract: Embodiments provided herein relate to methods and compositions for treating or preventing cancer. More particularly, several embodiments are drawn to treating or preventing malignant mesothelioma with antagonists of HMGB1.
    Type: Application
    Filed: June 7, 2012
    Publication date: May 8, 2014
    Inventors: Haining Yang, Michele Carbone, Marco E. Bianchi
  • Systems and Methods for Diagnosing a Predisposition to Develop Cancer
    Publication number: 20140011699
    Abstract: Systems, methods, and computer readable media for diagnosing or characterizing a genetic predisposition to develop cancer are provided. Nucleic acids comprising a germline nucleic acid sequence encoding the BRCA1 associated protein 1 are sequenced or probed to determine if the nucleic acid sequence includes alterations that predispose a subject to develop cancer.
    Type: Application
    Filed: February 17, 2012
    Publication date: January 9, 2014
    Inventors: Joseph R. Testa, Michele Carbone, Mitchell Cheung, Jianming Pei
  • SYSTEMS AND METHODS FOR DIAGNOSING A PREDISPOSITION TO DEVELOP CANCER
    Publication number: 20140010802
    Abstract: Systems, methods, and computer readable media for diagnosing or characterizing a genetic predisposition to develop cancer, including cancers of the BAP1 cancer syndrome, are provided. Nucleic acids comprising a germline nucleic acid sequence encoding the BRCA1 associated protein 1 (BAP1) are sequenced or probed to determine if the nucleic acid sequence includes alterations that predispose a subject to develop cancer.
    Type: Application
    Filed: August 19, 2013
    Publication date: January 9, 2014
    Applicants: University of Hawaii, Office of Technology Transfer and Economic Development, Institute for Cancer Research d/b/a The Research Institute of Fox Chase Cancer Center ("Fox Chase C
    Inventors: Joseph R. Testa, Michele Carbone, Mitchell Cheung, Jianming Pei