Patents by Inventor Michele Freche

Michele Freche has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6923989
    Abstract: A method for preparing a calcium phosphate pasty material for injection which after, setting, is designed to form an apatite material consists in: producing from water and calcium phosphates pasty mixture capable of developing, hardening and forming a hydroxyapatite. The method is characterised in that it consists in adding to the calcic phosphates or to the pasty mixture before it is injected a methicone having relative to the mixture more than 0.30 wt. % and less than 10 wt. %. The resulting material can be injected, that is it can be transported in pasty form into a conduit under moderate pressure levels. The material sets on the site of implantation and hardens to form an apatite biomaterial in a manner similar to known methicone-free calcium phosphate mixtures.
    Type: Grant
    Filed: February 27, 2001
    Date of Patent: August 2, 2005
    Assignee: Ceravic
    Inventors: Jean-Louis Lacout, Michèle Freche, Stephane Goncalves, Fernand Rodriguez
  • Publication number: 20030108589
    Abstract: A solid powder product with a Ca/P ratio of between 1.40 and 1.90 is prepared from tricalcium phosphate and tetracalcium phosphate. An aqueous solution containing calcium ions and phosphate ions with a Ca/P ratio higher than 0.20 and lower than 0.50 is prepared. The aqueous solution and the solid powder product and optionally water are mixed to obtain a mixture with a liquid/solid weight ratio of between 0.30 and 0.65 and a resulting paste with a Ca/P ratio of between 1.50 and 1.67.
    Type: Application
    Filed: January 13, 2003
    Publication date: June 12, 2003
    Applicant: TEKNIMED
    Inventors: Jean Louis Lacout, Zineb Hatim, Michele Freche-Botton
  • Publication number: 20030021824
    Abstract: The invention concerns a method for preparing a calcium phosphate pasty material for injection which after, setting, is designed to form an apatite material. Said method consists in: producing from water and calcium phosphates pasty mixture capable of developing, hardening and forming a hydroxyapatite. Said method is characterized in that it consists in adding to the calcic phosphates or to the pasty mixture before it is injected a methicone having relative to the mixture more than 0.30 wt. % and less than 10 wt. %. The resulting material can be injected, that is it can be transported in pasty form into a conduit under moderate pressure levels. Said material sets on the site of implantation and hardens to form an apatite biomaterial in a manner similar to known methicone-free calcium phosphate mixtures.
    Type: Application
    Filed: August 27, 2002
    Publication date: January 30, 2003
    Inventors: Jean-Louis Lacout, Michele Freche, Stephane Goncalves, Fernand Rodriguez
  • Patent number: 6338810
    Abstract: A process for manufacturing an apatite ceramic, especially for biological use involves the preparation of a homogeneous mixture of powders to form a hydroxyapatite of formula Ca10(PO4)6(OH)2, stoichiometric or non-stoichiometric, possibly containing other additives or flaws, compacting the mixture under a pressure of 100 to 500 Mpa at room temperature, and subjecting it to hydrothermal treatment at low temperature (100 to 500° C.) in the presence of water and in a sealed chamber.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: January 15, 2002
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Joëlle Carpena, Benoît Donazzon, Jean-Louis Lacout, Michèle Freche