Patents by Inventor Michele Mock

Michele Mock has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090110700
    Abstract: The invention concerns an acellular immunogenic or vaccine composition for producing antibodies against Bacillus anthracis comprising a protective antigen (PA) and killed and optionally purified spores, obtained from mutating strains of Bacillus anthracis and their uses.
    Type: Application
    Filed: December 22, 2008
    Publication date: April 30, 2009
    Applicants: INSTITUT PASTEUR, Centre National De La Recherche Scient
    Inventor: Michele MOCK
  • Patent number: 7491404
    Abstract: The invention concerns an acellular immunogenic or vaccine composition for producing antibodies against Bacillus anthracis comprising a protective antigen (PA) and killed and optionally purified spores, obtained from mutating strains of Bacillus anthracis and their uses.
    Type: Grant
    Filed: September 15, 2005
    Date of Patent: February 17, 2009
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique-CNRS
    Inventor: Michele Mock
  • Publication number: 20060099228
    Abstract: The invention concerns an acellular immunogenic or vaccine composition for producing antibodies against Bacillus anthracis comprising a protective antigen (PA) and killed and optionally purified spores, obtained from mutating strains of Bacillus anthracis and their uses.
    Type: Application
    Filed: September 15, 2005
    Publication date: May 11, 2006
    Applicants: INSTITUT PASTEUR, Centre National De La Recherche Scient.
    Inventor: Michele Mock
  • Patent number: 6979449
    Abstract: The invention concerns an acellular immunogenic or vaccine composition for producing antibodies against Bacillus anthracis comprising a protective antigen (PA) and killed and optionally purified spores, obtained from mutating strains of Bacillus anthracis and their uses.
    Type: Grant
    Filed: September 8, 2000
    Date of Patent: December 27, 2005
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique-CNRS
    Inventor: Michèle Mock
  • Patent number: 5840312
    Abstract: A recombinant strain of B. anthracis is characterized in that it can induce the production of protective antibodies against virulent strains of B. anthracis in a human or animal host, and characterized also by the mutation of the pX01 plasmid of at least one given gene coding for a protein which causes a toxic effect of B. anthracis, wherein said mutation leads to the deletion of all or part of said gene which codes for the protein causing the toxic effect, and to the insertion of a DNA cassette at said gene's deletion site in pX01, whereby the strain thereby modified may be selected and a back mutation of the recombinant strain may be prevented, and wherein the gene thereby mutated is thereafter either unable to produce the protein causing the toxic effect for which it codes, or able to code for a truncated protein which has lost its toxic properties. The use of such a strain in immunogenic compositions is also described.
    Type: Grant
    Filed: October 19, 1994
    Date of Patent: November 24, 1998
    Assignee: Institut Pasteur
    Inventors: Michele Mock, Angel Cataldi, Corinne Pezard