Patents by Inventor Michele O'Callaghan

Michele O'Callaghan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250075509
    Abstract: A system includes an elongated tube, a foam sleeve, and a plurality of supports. The foam sleeve is configured to be positioned around the elongated tube. The plurality of supports are configured to be attached to the elongated tube. Each of the plurality of supports includes a respective flange configured to be mounted against a wall. The elongated tube may comprise a plurality of tubular sections joined end-to-end, each tubular section having a male connector at a first end and a female connector at a second end opposite the first end. The male connector of a first tube is configured to engage a female connector of a second tube.
    Type: Application
    Filed: November 20, 2024
    Publication date: March 6, 2025
    Inventors: Michele O. Jorge, Madeline Rodriguez
  • Patent number: 12037371
    Abstract: Provided herein are novel proteins and protein domains from newly discovered anaerobic fungal species. The anaerobic fungal species have unique enzymatic capabilities, including the ability to digest diverse lignocellulosic biomass feedstocks and to synthesize secondary metabolites. The scope of the invention encompasses novel engineered proteins comprising glycoside hydrolase enzymes, dockerin domains, carbohydrate binding domains, and polyketide synthase enzymes. The invention further encompasses artificial cellulosomes comprising novel proteins and domains of the invention. The scope of the invention further includes novel nucleic acid sequences coding for the engineered proteins of the invention, and methods of using such engineered organisms to degrade lignocellulosic biomass and to create polyketides.
    Type: Grant
    Filed: May 17, 2021
    Date of Patent: July 16, 2024
    Assignee: The Regents of the University of California
    Inventors: Michelle O'Malley, Kevin Solomon, Charles Haitjema
  • Publication number: 20240082243
    Abstract: Disclosed herein are compounds that can bind to tubulin and activate GEF-H1. Methods of using these compounds for treating cancer are also disclosed.
    Type: Application
    Filed: April 24, 2023
    Publication date: March 14, 2024
    Inventors: Lan HUANG, Santosh Ambadas KHEDKAR, Michel O. STEINMETZ
  • Patent number: 11896628
    Abstract: Disclosed herein are compositions and methods for preventing, ameliorating, or treating Clostridium difficile infections and/or reducing the severity of one or more risk factors, signs, or symptoms associated with C. difficile infections. In particular, the technology of the present disclosure relates to methods for administering an effective amount of a composition comprising strains of Bacillus amyloliquefaciens bacteria identified as ART24, ART4, and ART 12, to a subject suffering from or at risk for C. difficile infections.
    Type: Grant
    Filed: July 1, 2022
    Date of Patent: February 13, 2024
    Assignee: Artugen Therapeutics Ltd.
    Inventors: Ronald Farquhar, Christopher K. Murphy, Colin Hill, Paul Ross, Mary Rea, Michelle O'Donnell, Brian Healy, Laurent Chesnel
  • Publication number: 20230397751
    Abstract: Embodiments include a bracket system for coupling to a wall having an exterior layer supported by a support beam. The bracket system includes an anchor having a flange, a stud portion extending rearwards, and a block portion extending frontwards. Embodiments also include a dual anchor system. The stud portion extends through the exterior layer to engage the support beam, or a support arm assembly. The flange engages a front surface of the exterior layer. The bracket includes a socket that slidably engages the block portion. When the block portion is engaged with the socket, a bolt hole of the block portion aligns with a bolt hole of the bracket. A bolt extends transversely through the bolt holes to secure the bracket to the anchor. The bracket includes a ring or can engage a rod. The rod can be releasably engaged with the bracket using a magnetic element.
    Type: Application
    Filed: April 6, 2023
    Publication date: December 14, 2023
    Inventors: Scott Montgomery, Steven Montgomery, Michelle O'neal
  • Publication number: 20230397779
    Abstract: Embodiments disclosed herein are directed to a bracket system for coupling to a wall, the wall having an exterior layer supported by a support beam. The bracket system includes an anchor having a flange, a stud portion extending rearwards, and a block portion extending frontwards. The stud portion extends through the exterior layer to engage the support beam directly. The flange can engage a front surface of the exterior layer. An anchor screw can extend through an anchor screw hole to secure the anchor to the support beam. A bracket can include a socket configured to slidably engage the block portion. When the block portion is engaged with the socket, a bolt hole of the block portion can align with a bolt hole of the bracket. A bolt can extend transversely through the bolt holes to secure the bracket to the anchor.
    Type: Application
    Filed: June 13, 2022
    Publication date: December 14, 2023
    Inventors: Steven Montgomery, Scott Montgomery, Michelle O'neal
  • Publication number: 20230295073
    Abstract: Described herein are methods of making crystalline Form 1 of 2-(4-methoxy-3-(3-methylphenethoxy)benzamido)-2,3-dihydro-1H-indene-2-carboxylic acid.
    Type: Application
    Filed: March 1, 2023
    Publication date: September 21, 2023
    Inventors: Denis BILLEN, Bénédicte MARTIN, Michelle O'MAHONY
  • Publication number: 20230132133
    Abstract: Disclosed herein are compositions and methods for preventing, ameliorating, or treating Clostridium difficile infections and/or reducing the severity of one or more risk factors, signs, or symptoms associated with C. difficile infections. In particular, the technology of the present disclosure relates to methods for administering an effective amount of a composition comprising strains of Bacillus amyloliquefaciens bacteria identified as ART24, ART4, and ART 12, to a subject suffering from or at risk for C. difficile infections.
    Type: Application
    Filed: July 1, 2022
    Publication date: April 27, 2023
    Applicant: Artugen Therapeutics Ltd.
    Inventors: Ronald Farquhar, Christopher K. Murphy, Colin Hill, Paul Ross, Mary Rea, Michelle O'Donnell, Brian Healy, Laurent Chesnel
  • Patent number: 11633393
    Abstract: Disclosed herein are compounds that can bind to tubulin and activate GEF-H1. Methods of using these compounds for treating cancer are also disclosed.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: April 25, 2023
    Assignee: BeyondSpring Pharmaceuticals, Inc.
    Inventors: Lan Huang, Santosh Ambadas Khedkar, Michel O. Steinmetz
  • Patent number: 11621081
    Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for obtaining data for a set of patients that each have a certain condition. A first and second sequence of data is determined based on the obtained data. A scoring model is generated by processing the first and second sequence of data to train a neural network. The scoring model determines a confidence that an individual has the particular healthcare condition. Patient scoring data is provided to the scoring model to determine the confidence that the individual has the healthcare condition. A confidence score is received as an output of the scoring model in response to providing the patient scoring data. The confidence score represents a determined confidence that the individual has the healthcare condition. An indication that represents the confidence that the individual has the healthcare condition is provided based on the received confidence score.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: April 4, 2023
    Assignee: IQVIA Inc.
    Inventors: Michelle O'Keefe, Lucas Glass, Kristy Morgan, Yunlong Wang, Yuliya Nigmatullina, Yilian Yuan, Yong Cai, Fan Zhang, Chaitanya Alamuri
  • Publication number: 20230000254
    Abstract: An extendable cushion assembly includes a cushion that is movable between an extended state and a retracted state, and a base upon which the cushion is removably coupled. The base is movable between an extended state and a retracted state. When the cushion is coupled to the base and when the base adopts the extended state or the retracted state the cushion is configured to adopt the extended or the retracted state respectively.
    Type: Application
    Filed: June 30, 2022
    Publication date: January 5, 2023
    Inventors: Michelle O'Doherty, James Gilmore, Chris Summerhill-Rutter
  • Patent number: 11465036
    Abstract: A portable rotatable spinner to be used in combination with a pencil and an educational curriculum worksheet, where the worksheet incorporates a spinner-type game board image, and where the game board is used by students to generate random results or data. The spinner has an arrow-shaped body. Located midpoint of the body is an integrally-formed, vertically-oriented cylinder. The cylinder extends symmetrically from the upper and lower surfaces of the body. Through the cylinder is a hole or aperture. The aperture has an internal diameter slightly larger than the diameter of a pencil. In use, the spinner is placed on top of the worksheet and aligned over the game board. A pencil is inserted through the spinner. One hand holds the pencil vertically while the other hand flicks the spinner. The spinner rotates freely about the pencil until coming to a rest.
    Type: Grant
    Filed: January 21, 2019
    Date of Patent: October 11, 2022
    Inventors: Patrick Allen O'Neill, Michele O'Neill
  • Patent number: 11419900
    Abstract: Disclosed herein are compositions and methods for preventing, ameliorating, or treating Clostridium difficile infections and/or reducing the severity of one or more risk factors, signs, or symptoms associated with C. difficile infections. In particular, the technology of the present disclosure relates to methods for administering an effective amount of a composition comprising strains of Bacillus amyloliquefaciens bacteria identified as ART24, ART4, and ART 12, to a subject suffering from or at risk for C. difficile infections.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: August 23, 2022
    Assignee: Artugen Therapeutics Ltd.
    Inventors: Ronald Farquhar, Christopher K. Murphy, Colin Hill, Paul Ross, Mary Rea, Michelle O'Donnell, Brian Healy, Laurent Chesnel
  • Patent number: 11319073
    Abstract: A sleeping apparatus comprising a textile fiber shell, a plurality of adjustable straps coupled to the textile fiber shell and a plurality of anchors, wherein each anchor is coupled to one of the plurality of adjustable straps, wherein the anchors are configured to attach to one or more structures such that the textile fiber shell forms a flat sleeping surface.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: May 3, 2022
    Inventor: Michelle O'Doherty
  • Publication number: 20210269492
    Abstract: Provided herein are novel proteins and protein domains from newly discovered anaerobic fungal species. The anaerobic fungal species have unique enzymatic capabilities, including the ability to digest diverse lignocellulosic biomass feedstocks and to synthesize secondary metabolites. The scope of the invention encompasses novel engineered proteins comprising glycoside hydrolase enzymes, dockerin domains, carbohydrate binding domains, and polyketide synthase enzymes. The invention further encompasses artificial cellulosomes comprising novel proteins and domains of the invention. The scope of the invention further includes novel nucleic acid sequences coding for the engineered proteins of the invention, and methods of using such engineered organisms to degrade lignocellulosic biomass and to create polyketides.
    Type: Application
    Filed: May 17, 2021
    Publication date: September 2, 2021
    Applicant: The Regents of the University of California
    Inventors: Michelle O'Malley, Kevin Solomon, Charles Haitjema
  • Publication number: 20210220411
    Abstract: Disclosed herein are compositions and methods for preventing, ameliorating, or treating Clostridium difficile infections and/or reducing the severity of one or more risk factors, signs, or symptoms associated with C. difficile infections. In particular, the technology of the present disclosure relates to methods for administering an effective amount of a composition comprising strains of Bacillus amyloliquefaciens bacteria identified as ART24, ART4, and ART 12, to a subject suffering from or at risk for C. difficile infections.
    Type: Application
    Filed: June 6, 2019
    Publication date: July 22, 2021
    Inventors: Ronald Farquhar, Christopher K. Murphy, Colin Hill, Paul Ross, Mary Rea, Michelle O'Donnell, Brian Healy, Laurent Chesnel
  • Patent number: 11021524
    Abstract: Provided herein are novel proteins and protein domains from newly discovered anaerobic fungal species. The anaerobic fungal species have unique enzymatic capabilities, including the ability to digest diverse lignocellulosic biomass feedstocks and to synthesize secondary metabolites. The scope of the invention encompasses novel engineered proteins comprising glycoside hydrolase enzymes, dockerin domains, carbohydrate binding domains, and polyketide synthase enzymes. The invention further encompasses artificial cellulosomes comprising novel proteins and domains of the invention. The scope of the invention further includes novel nucleic acid sequences coding for the engineered proteins of the invention, and methods of using such engineered organisms to degrade lignocellulosic biomass and to create polyketides.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: June 1, 2021
    Assignee: The Regents of the University of California
    Inventors: Michelle O'Malley, Kevin Solomon, Charles Haitjema
  • Patent number: 10959903
    Abstract: A system for coupling a user to a support apparatus includes a harness for the user, a hoist, and frame. The harness and the hoist have co-operable attachment means for releasably coupling the harness to the hoist. The frame is configured to receive the user, where the harness and the frame have co-operable attachment means for releasably coupling the harness to the frame.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: March 30, 2021
    Assignee: James Leckey Design Limited
    Inventors: Christopher McNicholl, Michelle O'Doherty
  • Publication number: 20200299338
    Abstract: Provided herein are novel proteins and protein domains from newly discovered anaerobic fungal species. The anaerobic fungal species have unique enzymatic capabilities, including the ability to digest diverse lignocellulosic biomass feedstocks and to synthesize secondary metabolites. The scope of the invention encompasses novel engineered proteins comprising glycoside hydrolase enzymes, dockerin domains, carbohydrate binding domains, and polyketide synthase enzymes. The invention further encompasses artificial cellulosomes comprising novel proteins and domains of the invention. The scope of the invention further includes novel nucleic acid sequences coding for the engineered proteins of the invention, and methods of using such engineered organisms to degrade lignocellulosic biomass and to create polyketides.
    Type: Application
    Filed: June 10, 2020
    Publication date: September 24, 2020
    Applicant: The Regents of the University of California
    Inventors: Michelle O'Malley, Kevin Solomon, Charles Haitjema
  • Publication number: 20200237754
    Abstract: Disclosed herein are compounds that can bind to tubulin and activate GEF-H1. Methods of using these compounds for treating cancer are also disclosed.
    Type: Application
    Filed: January 5, 2018
    Publication date: July 30, 2020
    Inventors: Lan HUANG, Santosh Ambadas KHEDKAR, Michel O. STEINMETZ