Patents by Inventor Michele O'Callaghan
Michele O'Callaghan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250075509Abstract: A system includes an elongated tube, a foam sleeve, and a plurality of supports. The foam sleeve is configured to be positioned around the elongated tube. The plurality of supports are configured to be attached to the elongated tube. Each of the plurality of supports includes a respective flange configured to be mounted against a wall. The elongated tube may comprise a plurality of tubular sections joined end-to-end, each tubular section having a male connector at a first end and a female connector at a second end opposite the first end. The male connector of a first tube is configured to engage a female connector of a second tube.Type: ApplicationFiled: November 20, 2024Publication date: March 6, 2025Inventors: Michele O. Jorge, Madeline Rodriguez
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Patent number: 12037371Abstract: Provided herein are novel proteins and protein domains from newly discovered anaerobic fungal species. The anaerobic fungal species have unique enzymatic capabilities, including the ability to digest diverse lignocellulosic biomass feedstocks and to synthesize secondary metabolites. The scope of the invention encompasses novel engineered proteins comprising glycoside hydrolase enzymes, dockerin domains, carbohydrate binding domains, and polyketide synthase enzymes. The invention further encompasses artificial cellulosomes comprising novel proteins and domains of the invention. The scope of the invention further includes novel nucleic acid sequences coding for the engineered proteins of the invention, and methods of using such engineered organisms to degrade lignocellulosic biomass and to create polyketides.Type: GrantFiled: May 17, 2021Date of Patent: July 16, 2024Assignee: The Regents of the University of CaliforniaInventors: Michelle O'Malley, Kevin Solomon, Charles Haitjema
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Publication number: 20240082243Abstract: Disclosed herein are compounds that can bind to tubulin and activate GEF-H1. Methods of using these compounds for treating cancer are also disclosed.Type: ApplicationFiled: April 24, 2023Publication date: March 14, 2024Inventors: Lan HUANG, Santosh Ambadas KHEDKAR, Michel O. STEINMETZ
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Patent number: 11896628Abstract: Disclosed herein are compositions and methods for preventing, ameliorating, or treating Clostridium difficile infections and/or reducing the severity of one or more risk factors, signs, or symptoms associated with C. difficile infections. In particular, the technology of the present disclosure relates to methods for administering an effective amount of a composition comprising strains of Bacillus amyloliquefaciens bacteria identified as ART24, ART4, and ART 12, to a subject suffering from or at risk for C. difficile infections.Type: GrantFiled: July 1, 2022Date of Patent: February 13, 2024Assignee: Artugen Therapeutics Ltd.Inventors: Ronald Farquhar, Christopher K. Murphy, Colin Hill, Paul Ross, Mary Rea, Michelle O'Donnell, Brian Healy, Laurent Chesnel
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Publication number: 20230397751Abstract: Embodiments include a bracket system for coupling to a wall having an exterior layer supported by a support beam. The bracket system includes an anchor having a flange, a stud portion extending rearwards, and a block portion extending frontwards. Embodiments also include a dual anchor system. The stud portion extends through the exterior layer to engage the support beam, or a support arm assembly. The flange engages a front surface of the exterior layer. The bracket includes a socket that slidably engages the block portion. When the block portion is engaged with the socket, a bolt hole of the block portion aligns with a bolt hole of the bracket. A bolt extends transversely through the bolt holes to secure the bracket to the anchor. The bracket includes a ring or can engage a rod. The rod can be releasably engaged with the bracket using a magnetic element.Type: ApplicationFiled: April 6, 2023Publication date: December 14, 2023Inventors: Scott Montgomery, Steven Montgomery, Michelle O'neal
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Publication number: 20230397779Abstract: Embodiments disclosed herein are directed to a bracket system for coupling to a wall, the wall having an exterior layer supported by a support beam. The bracket system includes an anchor having a flange, a stud portion extending rearwards, and a block portion extending frontwards. The stud portion extends through the exterior layer to engage the support beam directly. The flange can engage a front surface of the exterior layer. An anchor screw can extend through an anchor screw hole to secure the anchor to the support beam. A bracket can include a socket configured to slidably engage the block portion. When the block portion is engaged with the socket, a bolt hole of the block portion can align with a bolt hole of the bracket. A bolt can extend transversely through the bolt holes to secure the bracket to the anchor.Type: ApplicationFiled: June 13, 2022Publication date: December 14, 2023Inventors: Steven Montgomery, Scott Montgomery, Michelle O'neal
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Publication number: 20230295073Abstract: Described herein are methods of making crystalline Form 1 of 2-(4-methoxy-3-(3-methylphenethoxy)benzamido)-2,3-dihydro-1H-indene-2-carboxylic acid.Type: ApplicationFiled: March 1, 2023Publication date: September 21, 2023Inventors: Denis BILLEN, Bénédicte MARTIN, Michelle O'MAHONY
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Publication number: 20230132133Abstract: Disclosed herein are compositions and methods for preventing, ameliorating, or treating Clostridium difficile infections and/or reducing the severity of one or more risk factors, signs, or symptoms associated with C. difficile infections. In particular, the technology of the present disclosure relates to methods for administering an effective amount of a composition comprising strains of Bacillus amyloliquefaciens bacteria identified as ART24, ART4, and ART 12, to a subject suffering from or at risk for C. difficile infections.Type: ApplicationFiled: July 1, 2022Publication date: April 27, 2023Applicant: Artugen Therapeutics Ltd.Inventors: Ronald Farquhar, Christopher K. Murphy, Colin Hill, Paul Ross, Mary Rea, Michelle O'Donnell, Brian Healy, Laurent Chesnel
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Patent number: 11633393Abstract: Disclosed herein are compounds that can bind to tubulin and activate GEF-H1. Methods of using these compounds for treating cancer are also disclosed.Type: GrantFiled: January 5, 2018Date of Patent: April 25, 2023Assignee: BeyondSpring Pharmaceuticals, Inc.Inventors: Lan Huang, Santosh Ambadas Khedkar, Michel O. Steinmetz
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Patent number: 11621081Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for obtaining data for a set of patients that each have a certain condition. A first and second sequence of data is determined based on the obtained data. A scoring model is generated by processing the first and second sequence of data to train a neural network. The scoring model determines a confidence that an individual has the particular healthcare condition. Patient scoring data is provided to the scoring model to determine the confidence that the individual has the healthcare condition. A confidence score is received as an output of the scoring model in response to providing the patient scoring data. The confidence score represents a determined confidence that the individual has the healthcare condition. An indication that represents the confidence that the individual has the healthcare condition is provided based on the received confidence score.Type: GrantFiled: November 13, 2018Date of Patent: April 4, 2023Assignee: IQVIA Inc.Inventors: Michelle O'Keefe, Lucas Glass, Kristy Morgan, Yunlong Wang, Yuliya Nigmatullina, Yilian Yuan, Yong Cai, Fan Zhang, Chaitanya Alamuri
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Publication number: 20230000254Abstract: An extendable cushion assembly includes a cushion that is movable between an extended state and a retracted state, and a base upon which the cushion is removably coupled. The base is movable between an extended state and a retracted state. When the cushion is coupled to the base and when the base adopts the extended state or the retracted state the cushion is configured to adopt the extended or the retracted state respectively.Type: ApplicationFiled: June 30, 2022Publication date: January 5, 2023Inventors: Michelle O'Doherty, James Gilmore, Chris Summerhill-Rutter
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Patent number: 11465036Abstract: A portable rotatable spinner to be used in combination with a pencil and an educational curriculum worksheet, where the worksheet incorporates a spinner-type game board image, and where the game board is used by students to generate random results or data. The spinner has an arrow-shaped body. Located midpoint of the body is an integrally-formed, vertically-oriented cylinder. The cylinder extends symmetrically from the upper and lower surfaces of the body. Through the cylinder is a hole or aperture. The aperture has an internal diameter slightly larger than the diameter of a pencil. In use, the spinner is placed on top of the worksheet and aligned over the game board. A pencil is inserted through the spinner. One hand holds the pencil vertically while the other hand flicks the spinner. The spinner rotates freely about the pencil until coming to a rest.Type: GrantFiled: January 21, 2019Date of Patent: October 11, 2022Inventors: Patrick Allen O'Neill, Michele O'Neill
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Patent number: 11419900Abstract: Disclosed herein are compositions and methods for preventing, ameliorating, or treating Clostridium difficile infections and/or reducing the severity of one or more risk factors, signs, or symptoms associated with C. difficile infections. In particular, the technology of the present disclosure relates to methods for administering an effective amount of a composition comprising strains of Bacillus amyloliquefaciens bacteria identified as ART24, ART4, and ART 12, to a subject suffering from or at risk for C. difficile infections.Type: GrantFiled: June 6, 2019Date of Patent: August 23, 2022Assignee: Artugen Therapeutics Ltd.Inventors: Ronald Farquhar, Christopher K. Murphy, Colin Hill, Paul Ross, Mary Rea, Michelle O'Donnell, Brian Healy, Laurent Chesnel
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Patent number: 11319073Abstract: A sleeping apparatus comprising a textile fiber shell, a plurality of adjustable straps coupled to the textile fiber shell and a plurality of anchors, wherein each anchor is coupled to one of the plurality of adjustable straps, wherein the anchors are configured to attach to one or more structures such that the textile fiber shell forms a flat sleeping surface.Type: GrantFiled: August 31, 2016Date of Patent: May 3, 2022Inventor: Michelle O'Doherty
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Publication number: 20210269492Abstract: Provided herein are novel proteins and protein domains from newly discovered anaerobic fungal species. The anaerobic fungal species have unique enzymatic capabilities, including the ability to digest diverse lignocellulosic biomass feedstocks and to synthesize secondary metabolites. The scope of the invention encompasses novel engineered proteins comprising glycoside hydrolase enzymes, dockerin domains, carbohydrate binding domains, and polyketide synthase enzymes. The invention further encompasses artificial cellulosomes comprising novel proteins and domains of the invention. The scope of the invention further includes novel nucleic acid sequences coding for the engineered proteins of the invention, and methods of using such engineered organisms to degrade lignocellulosic biomass and to create polyketides.Type: ApplicationFiled: May 17, 2021Publication date: September 2, 2021Applicant: The Regents of the University of CaliforniaInventors: Michelle O'Malley, Kevin Solomon, Charles Haitjema
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Publication number: 20210220411Abstract: Disclosed herein are compositions and methods for preventing, ameliorating, or treating Clostridium difficile infections and/or reducing the severity of one or more risk factors, signs, or symptoms associated with C. difficile infections. In particular, the technology of the present disclosure relates to methods for administering an effective amount of a composition comprising strains of Bacillus amyloliquefaciens bacteria identified as ART24, ART4, and ART 12, to a subject suffering from or at risk for C. difficile infections.Type: ApplicationFiled: June 6, 2019Publication date: July 22, 2021Inventors: Ronald Farquhar, Christopher K. Murphy, Colin Hill, Paul Ross, Mary Rea, Michelle O'Donnell, Brian Healy, Laurent Chesnel
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Patent number: 11021524Abstract: Provided herein are novel proteins and protein domains from newly discovered anaerobic fungal species. The anaerobic fungal species have unique enzymatic capabilities, including the ability to digest diverse lignocellulosic biomass feedstocks and to synthesize secondary metabolites. The scope of the invention encompasses novel engineered proteins comprising glycoside hydrolase enzymes, dockerin domains, carbohydrate binding domains, and polyketide synthase enzymes. The invention further encompasses artificial cellulosomes comprising novel proteins and domains of the invention. The scope of the invention further includes novel nucleic acid sequences coding for the engineered proteins of the invention, and methods of using such engineered organisms to degrade lignocellulosic biomass and to create polyketides.Type: GrantFiled: June 10, 2020Date of Patent: June 1, 2021Assignee: The Regents of the University of CaliforniaInventors: Michelle O'Malley, Kevin Solomon, Charles Haitjema
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Patent number: 10959903Abstract: A system for coupling a user to a support apparatus includes a harness for the user, a hoist, and frame. The harness and the hoist have co-operable attachment means for releasably coupling the harness to the hoist. The frame is configured to receive the user, where the harness and the frame have co-operable attachment means for releasably coupling the harness to the frame.Type: GrantFiled: June 29, 2018Date of Patent: March 30, 2021Assignee: James Leckey Design LimitedInventors: Christopher McNicholl, Michelle O'Doherty
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Publication number: 20200299338Abstract: Provided herein are novel proteins and protein domains from newly discovered anaerobic fungal species. The anaerobic fungal species have unique enzymatic capabilities, including the ability to digest diverse lignocellulosic biomass feedstocks and to synthesize secondary metabolites. The scope of the invention encompasses novel engineered proteins comprising glycoside hydrolase enzymes, dockerin domains, carbohydrate binding domains, and polyketide synthase enzymes. The invention further encompasses artificial cellulosomes comprising novel proteins and domains of the invention. The scope of the invention further includes novel nucleic acid sequences coding for the engineered proteins of the invention, and methods of using such engineered organisms to degrade lignocellulosic biomass and to create polyketides.Type: ApplicationFiled: June 10, 2020Publication date: September 24, 2020Applicant: The Regents of the University of CaliforniaInventors: Michelle O'Malley, Kevin Solomon, Charles Haitjema
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Publication number: 20200237754Abstract: Disclosed herein are compounds that can bind to tubulin and activate GEF-H1. Methods of using these compounds for treating cancer are also disclosed.Type: ApplicationFiled: January 5, 2018Publication date: July 30, 2020Inventors: Lan HUANG, Santosh Ambadas KHEDKAR, Michel O. STEINMETZ